Mostrando 2,401 - 2,420 Resultados de 147,287 Para Buscar '"translator"', tiempo de consulta: 0.93s Limitar resultados
  1. 2401
    “…In this work, we treated two distinct strains of C. auris for 24 h with caspofungin, and the cellular responses were evaluated at the morphological, translational and transcriptional levels. We first observed that the echinocandin caused morphological alterations, aggregation of yeast cells, and modifications in the cell wall composition of C. auris. …”
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  2. 2402
  3. 2403
    “…Importantly, endosome‐coupled translation of mRNAs encoding mitochondrial proteins, for example, seems to be particularly important for efficient organelle import and for regulating subcellular mitochondrial activity. …”
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  4. 2404
    “…Interestingly, accumulating evidence has identified that transfer RNAs (tRNAs) and tRNA metabolism–associated enzymes not only participate in the protein translation but also play an important role in the occurrence and development of lung cancer. …”
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  5. 2405
    por Lalanne, Jean-Benoît, Li, Gene-Wei
    Publicado 2021
    “…Here, we report a biophysical, first-principles model of growth optimization for core mRNA translation, a multi-enzyme system that involves proteins with a broadly conserved stoichiometry spanning two orders of magnitude. …”
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  6. 2406
  7. 2407
    por Pence, Isaac J., Evans, Conor L.
    Publicado 2021
    “…Here we review the mechanisms and clinical applications of Raman scattering, specifically focusing on high-speed imaging methods that can provide spatial context for translational biomedical applications.…”
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  8. 2408
    “…There is an urgent need for academia to fully integrate the basic research and clinical data from PC to form a research model conducive to clinical translation and promote the proper treatment of PC. …”
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  9. 2409
  10. 2410
    por Chen, Haidan
    Publicado 2021
    “…Despite enthusiasm for stem cell therapy, the clinical and translational research of stem cells overall has been a slow and cumbersome process. …”
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  11. 2411
    “…However, almost all these methods depend on the translation elongation process, and strategies leveraging the initiation process have rarely been reported. …”
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  12. 2412
    “…In vivo and ex vivo studies of [(177)Lu]Lu-AAZTA(5).SA.KuE, [(44)Sc]Sc-AAZTA(5).SA.KuE and [(68)Ga]Ga-DATA(5m).SA.KuE displayed specific accumulation in the tumor along with fast clearance and reduced off-target uptake. (4) Conclusions: Both KuE-conjugates showed promising properties especially in vivo allowing for translational theranostic use.…”
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  13. 2413
  14. 2414
    “…METHODS: According to guidelines for cross-cultural adaptation, translation of the English version of the FJS was performed. …”
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  15. 2415
    “…Whilst previous models of autoinhibition of transcription have tended to treat processes such as translation as being unregulated (and hence linear), here we develop and explore a mathematical model that considers autoinhibition of transcription together with nonlinear regulation of translation. …”
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  17. 2417
  18. 2418
  19. 2419
    “…We then discuss how post-translational modifications, such as phosphorylation and ubiquitination, shape their composition and functions. …”
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  20. 2420
    “…Oral bacteria colonize the oral cavity, surrounding complex and variable environments. Post-translational modifications (PTMs) are an efficient biochemical mechanism across all domains of life. …”
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