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2721por Tierney, Jack A. S., Świrski, Michał, Tjeldnes, Håkon, Mudge, Jonathan M., Kufel, Joanna, Whiffin, Nicola, Valen, Eivind, Baranov, Pavel V.“…However, current schematic or annotation-based representations of mRNA translation generally do not account for the apparent multitude of translated regions within the same molecules. …”
Publicado 2023
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2722por Kirshina, Anna, Vasileva, Olga, Kunyk, Dmitry, Seregina, Kristina, Muslimov, Albert, Ivanov, Roman, Reshetnikov, Vasiliy“…The cellular data enabled us to identify the best seven combinations of 5′- and 3′UTRs, whose translational efficiency was then assessed in BALB/c mice. …”
Publicado 2023
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2723por Batra, Harsh, Mouabbi, Jason Aboudi, Ding, Qingqing, Sahin, Aysegul A., Raso, Maria Gabriela“…In this review, we highlighted the most important recent and relevant developments that have happened in the ILC domain, including histology and integrating advances in genomics and the overall translational medicine aspects of ILC. ABSTRACT: The second most common breast carcinoma, invasive lobular carcinoma, accounts for approximately 15% of tumors of breast origin. …”
Publicado 2023
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2724por Platz, Karlie R., Rudisel, Emma J., Paluch, Katelynn V., Laurin, Taylor R., Dittenhafer-Reed, Kristin E.“…The mitochondrial proteome is subject to abundant post-translational modifications, including lysine acetylation and phosphorylation of serine, threonine, and tyrosine. …”
Publicado 2023
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2725por Wang, Zhe, Wang, Xinpei, Xu, Wanting, Li, Yongxiao, Lai, Ruizhi, Qiu, Xiaohui, Chen, Xu, Chen, Zhidong, Mi, Bobin, Wu, Meiying, Wang, Junqing“…This review provides an overview of BDSs and delves into the multifaceted translational challenges and present emerging solutions, underscored by real-world case studies. …”
Publicado 2023
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2726por Andersson, Sofia, Granat, Lisa, Baxter, Rebecca, Reimertz, Helene, Modéus, Carina, Pusa, Susanna, Sandgren, Anna“…Objective: To translate and adapt the Serious Illness Conversation Guide for use within the Swedish healthcare setting and examine the validity and acceptability of the Swedish Serious Illness Conversation Guide. …”
Publicado 2023
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2727
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2728“…Translation of an mRNA is generally divided into three stages: initiation, elongation and termination. …”
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2729por Lee, Tzong-Yi, Huang, Hsien-Da, Hung, Jui-Hung, Huang, Hsi-Yuan, Yang, Yuh-Shyong, Wang, Tzu-Hao“…dbPTM is a database that compiles information on protein post-translational modifications (PTMs), such as the catalytic sites, solvent accessibility of amino acid residues, protein secondary and tertiary structures, protein domains and protein variations. …”
Publicado 2006
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2730“…The lack of splicing can significantly reduce the efficiency of their translation. Some retroviruses contain a 5' terminal post-transcriptional control element (PCE) that facilitates translation of unspliced mRNA. …”
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2731
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2732por Anastasiou, Foteini, Antonakis, Nikos, Chaireti, Georgia, Theodorakis, Pavlos N, Lionis, Christos“…This paper reports on the validation and translation into Greek, of an English questionnaire for the identification of dyspepsia in the general population and discusses several possibilities of its use in the Greek primary care. …”
Publicado 2006
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2733“…We demonstrate that Alu RNPs and Alu RNAs do not stably associate with ribosomes during translation and, based on the analysis of polysome profiles and synchronized translation, we show that Alu RNP and Alu RNA regulate translation at the level of initiation.…”
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2734“…The Editorial Board of Journal of Translational Medicine is pleased to announce a prize to recognize outstanding contributions in the field of translational medicine. …”
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2735por Cobucci-Ponzano, Beatrice, Conte, Fiorella, Benelli, Dario, Londei, Paola, Flagiello, Angela, Monti, Maria, Pucci, Piero, Rossi, Mosè, Moracci, Marco“…The standard rules of genetic translational decoding are altered in specific genes by different events that are globally termed recoding. …”
Publicado 2006
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2736“…However, such an anticodon would impose selection against the use of AUA codons because AUA needs to be wobble-translated. According to this translation conflict hypothesis, AUA should be used relatively less frequently compared to UUA in the UUR codon family. …”
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2737
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2738por Saguy, Matthieu, Gillet, Reynald, Skorski, Patricia, Hermann-Le Denmat, Sylvie, Felden, Brice“…Overall, these results demonstrate that S1 has a role in tmRNA-mediated tagging that is distinct from its role during canonical translation.…”
Publicado 2007
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2739“…Internationally recommended methodology, mandating forward translation, backward translation, reconciliation and pretesting steps, was followed. …”
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2740por Jiang, Hong, Coleman, Jennifer, Miskimins, Robin, Srinivasan, Rekha, Miskimins, W. Keith“…Several recent publications have explored cap-independent translation through an internal ribosome entry site (IRES) in the 5′-UTR of the mRNA encoding the cyclin-dependent kinase inhibitor p27. …”
Publicado 2007
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