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2741Publicado 1982“…However, after fertilization, both CS and alpha messages are translated. Since alpha histone mRNA isolated from unfertilized eggs can be translated in vitro, the synthesis of alpha histone subtypes appears to be under translational control. …”
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2742
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2743Publicado 1986“…Another nuclear product is specifically required for translation of mRNA encoding the 32-34-kD polypeptide, D1. …”
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2744Publicado 1990“…Using allelic variants of the AChE polypeptide chains as genetic markers, we show that nuclei homozygous for either the alpha or beta alleles residing in chimeric myotubes preferentially translate their AChE mRNAs on their respective ERs. …”
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2745Publicado 1993“…The purposes of this study were: (a) to measure the translational mobility of a small solute in cell cytoplasm; (b) to define quantitatively the factors that determine solute translation; and (c) to compare and contrast solute rotation and translation. …”
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2746por Chiappelli, Francesco, Prolo, Paolo, D. Cajulis, Kristine, Angeli, Alberto, Dovio, Andrea, Perotti, Paola, Pautasso, Marisa, Luisa Sartori, Maria, Saba, Laura, Mussino, Stefano, Fraccalini, Thomas, Fanto, Fausto, Manfrini, Ercolano, Mocellini, Cristina, Gabriella Rosso, Maria, Grasso, Enzo“…Our observations suggest that psychoimmune measures such as those we have monitored in this study provide relevant information about the evolving physiological modulation in patients with sDAT during progression of Alzheimer's disease, and point to new or improved translational epigenetic treatment interventions.…”
Publicado 2007
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2747
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2748por Dixon, Dan A., Balch, Glen C., Kedersha, Nancy, Anderson, Paul, Zimmerman, Guy A., Beauchamp, R. Daniel, Prescott, Stephen M.“…RNA binding studies, performed to identify ARE-binding regulatory factors, demonstrated binding of the translational repressor protein TIA-1 to COX-2 mRNA. …”
Publicado 2003
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2749“…Two stress-resistant clones were isolated which contain antisense gene fragments of the translation initiation factor (eIF)2α and express a low amount of eIF2α. …”
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2750Publicado 1991“…Scrutiny of vertebrate cDNA sequences in light of these criteria reveals a set of transcripts--encoding oncoproteins, growth factors, transcription factors, and other regulatory proteins--that seem designed to be translated poorly. Thus, throttling at the level of translation may be a critical component of gene regulation in vertebrates. …”
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2751por Ribrioux, Sebastien, Brüngger, Adrian, Baumgarten, Birgit, Seuwen, Klaus, John, Markus R“…BACKGROUND: Exceptionally, a single nucleotide sequence can be translated in vivo in two different frames to yield distinct proteins. …”
Publicado 2008
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2752por Larsson, Ola, Diebold, Deanna, Fan, Danhua, Peterson, Mark, Nho, Richard Seonghun, Bitterman, Peter B., Henke, Craig A.“…To determine the effect of matrix state on translational control, myofibroblasts were permitted to contract the matrix. …”
Publicado 2008
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2753“…Summary: The Synergizer is a database and web service that provides translations of biological database identifiers. It is accessible both programmatically and interactively. …”
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2754por Peterson, Kevin A., Radosevich, David M., O'Connor, Patrick J., Nyman, John A., Prineas, Ronald J., Smith, Steven A., Arneson, Thomas J., Corbett, Victor A., Weinhandl, Joyce C., Lange, Carol J., Hannan, Peter J.“…RESEARCH DESIGN AND METHODS—This was a group-randomized, controlled clinical trial evaluating the practical effectiveness of a multicomponent intervention (TRANSLATE) in 24 practices. The intervention included implementation of an electronic diabetes registry, visit reminders, and patient-specific physician alerts. …”
Publicado 2008
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2755por Shapshak, Paul, Chiappelli, Francesco, Commins, Deborah, Singer, Elyse, Levine, Andrew J, Somboonwit, Charurut, Minagar, Alireza, Pellionisz, Andras J“…We discuss the general implications of molecular epigenetics with special emphasis on drug abuse, bar-codes, pyknons, and miRNAs for translational and clinical research. We discuss the application of the recent recursive algorithm of biology to this field and propose to synthesize the Genomic and Epigenomic views into a holistic approach of HoloGenomics.…”
Publicado 2008
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2756por Mankoff, David A“…This review briefly describes different imaging modalities used in molecular imaging and then reviews applications of molecular imaging to breast cancer, with a focus on translational work. It includes sections describing work in functional and physiological tumor imaging, imaging gene product expression, imaging the tumor microenvironment, reporter gene imaging, and cell labeling. …”
Publicado 2008
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2757por Pacheco, Almudena, de Quinto, Sonia López, Ramajo, Jorge, Fernández, Noemí, Martínez-Salas, Encarnación“…Functional analysis performed in Gemin5 shRNA-depleted cells, or in in vitro translation reactions, revealed an unanticipated role of Gemin5 in translation control as a down-regulator of cap-dependent and IRES-driven translation initiation. …”
Publicado 2009
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2758por Hamanaka, Robert B., Bobrovnikova-Marjon, Ekaterina, Ji, Xinjun, Liebhaber, Stephen A., Diehl, J. Alan“…This induction of IAPs occurs through both transcriptional and translational responses that are PERK-dependent. Reintroduction of cIAP1 or cIAP2 expression into PERK−/− MEFs during ER stress delays the early onset of ER stress-induced caspase activation and apoptosis observed in these cells. …”
Publicado 2008
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2759
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2760