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  1. 2761
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    Genome-wide association studies in pharmacogenomics: untapped potential for translation
  2. 2762
    por Ferring, Dieter
    Publicado 2009
    “…Persons trained in translational education will thus be able to integrate several disciplinary knowledge domains and translate new developments in basic research to their application. …”
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    Bridging education and training in ageing and disabilities: towards translational education
  3. 2763
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    The "Excellence in Translational Medicine" and "Bedside-to-Bench" Awards 2007–08
  4. 2764
    por Chen, Hai-Feng
    Publicado 2009
    “…NMR spectra suggest that apo-KID is an unstructured protein. After post-translational modification by phosphorylation, KID undergoes a transition from disordered to well folded protein upon binding to KIX. …”
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    Molecular Dynamics Simulation of Phosphorylated KID Post-Translational Modification
  5. 2765
    “…In fact, other components of translational machinery such as eIF2α, eIF3b, eIF4E, eEF2 and ribosomal P protein are enriched in areas surrounding ASFV factories. …”
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    Regulation of Host Translational Machinery by African Swine Fever Virus
  6. 2766
    “…Our understanding of causes and consequences of post-translational modification of polycomb proteins will gain significantly from in vivo validation experiments. …”
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    Talking to chromatin: post-translational modulation of polycomb group function
  7. 2767
    “…The issue is how we can facilitate a translational approach between researchers in the two fields. …”
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    Perspectives on Sensory Processing Disorder: A Call for Translational Research
  8. 2768
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    Translating the oxidative stress hypothesis into the clinic: NOX versus NOS
  9. 2769
    “…We demonstrate that the AGG interruptions have no detectable influence on translational efficiency in either a cell-free system or cell culture, indicating that any AGG-repeat-induced alterations in secondary/tertiary structure, if present, do not involve the rate-limiting step(s) in translational initiation.…”
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    Translation of the FMR1 mRNA is not influenced by AGG interruptions
  10. 2770
    “…Requirements for synthetic polymer evolution include: (i) sequence-specific polymerization of synthetic building blocks on an amplifiable template; (ii) display of the newly translated polymer strand in a manner that allows it to adopt folded structures; (iii) selection of synthetic polymer libraries for desired binding or catalytic properties; and (iv) amplification of template sequences surviving selection in a manner that allows subsequent translation. …”
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    An In Vitro Translation, Selection, and Amplification System for Peptide Nucleic Acids
  11. 2771
    “…We thus argue for sincere caution in the translation of functional neuroimaging to real-world applications.…”
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    fMRI in Translation: The Challenges Facing Real-World Applications
  12. 2772
    “…Separately, upstream AUGs (uAUGs) in 5'-UTRs are known to regulate genes translationally without affecting mRNA levels, one of the mechanisms for miRNA-mediated repression. …”
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    Unified translation repression mechanism for microRNAs and upstream AUGs
  13. 2773
    “…CONCLUSIONS: Our analysis of the transient protein translation dynamics shows that it gives enough information to verify or reject a hypothesis about a particular molecular mechanism of microRNA action on protein translation. …”
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    Dynamical modeling of microRNA action on the protein translation process
  14. 2774
    “…Increasing the number of correct identifications, both of genes and of the translation initiation sites for each gene, and reducing the overall number of false positives, are all desirable goals. …”
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    Prodigal: prokaryotic gene recognition and translation initiation site identification
  15. 2775
    “…Further evidence suggests that it was within this RNA-based genetic system that life developed the ability to synthesize proteins by translating genetic code. Here we investigate the early development of the translation system through an evolutionary survey of protein architectures associated with modern translation. …”
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    The evolution and functional repertoire of translation proteins following the origin of life
  16. 2776
    por Oberle, C., Blattner, C.
    Publicado 2010
    “…More recent research shows that the formation of many of these aggregates depends on post-translational modifications. In this article, we have summarized the different cellular events in response to a DNA double strand break, the most severe lesion of the DNA.…”
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    Regulation of the DNA Damage Response to DSBs by Post-Translational Modifications
  17. 2777
    “…The translation of genetic information according to the sequence of the mRNA template occurs with high accuracy and fidelity. …”
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    Global and local depletion of ternary complex limits translational elongation
  18. 2778
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    The "Excellence in Translational Medicine" and "Bedside-to-Bench" Awards 2008-09
  19. 2779
    “…The absence or severe reduction of protein demonstrated their deleterious effect at translational level. We concluded that bioinformatic tools are valuable to suggest the potential effects of intronic variants; however, the experimental demonstration of the pathogenicity is not always easy to do even when using RNA analysis (low abundance, degradation mechanisms), and it might not be successful unless splicing-specific-PCR tests are used. …”
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    Transcriptional and Translational Effects of Intronic CAPN3 Gene Mutations
  20. 2780
    “…BACKGROUND: Knowledge translation (KT) is a rapidly growing field that is becoming an integral part of research protocols. …”
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    The trainees' perspective on developing an end-of-grant knowledge translation plan
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