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  1. 2821
    Publicado 2012
    “…In this interview, she discusses her early career, key issues in successful clinical translation and her move to become Dean of Weill Cornell Medical College in Manhattan.…”
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  2. 2822
    “…In organello translation in isolated mitochondria was inhibited by type A and B trichothecenes, demonstrating that these toxins have a direct effect on mitochondrial translation. …”
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  3. 2823
    “…Here, we discuss recent findings related to LRRK2-mediated regulation of gene expression and translation and provide a critical assessment of the current models that are used to address the impact of LRRK2 on the transcriptome. …”
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  4. 2824
  5. 2825
  6. 2826
    por Tsuchihashi, Z
    Publicado 1991
    “…Production of the gamma subunit of Escherichia coli DNA polymerase III holoenzyme is dependent on a very efficient translational frameshif in the dnaX gene. I used an E. coli in vitro translation system to analyze the mechanism of this frameshifting event. …”
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  7. 2827
  8. 2828
    “…CONCLUSIONS: The SPF provides a unified framework to effectively manage provenance of translational research data during pre and post-publication phases. …”
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  9. 2829
  10. 2830
    “…Axonal ribosome immunoprecipitation confirmed translation of lb2 mRNA in vivo. Inhibition of lb2 mRNA translation in axons in vivo does not affect guidance but causes axonal degeneration. …”
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  11. 2831
    “…Whether protein translation occurs in the nucleus is contentious. To address this question, we developed the ribopuromycylation method (RPM), which visualizes translation in cells via standard immunofluorescence microscopy. …”
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  12. 2832
    “…DAZ family proteins are thought to activate the translation of RNA targets, but recent work has uncovered additional functions. …”
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  13. 2833
    “…This motif mediates Lin28-dependent stimulation of translation. As Lin28 is also known to inhibit the biogenesis of a cohort of miRNAs including let-7, we propose that Lin28 binding to different RNA types (precursor miRNAs versus mRNAs) may facilitate recruitment of different co-factors, leading to distinct regulatory outcomes. …”
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  14. 2834
  15. 2835
    “…Moderate translation rates allow coupling of peptide synthesis and membrane targeting, resulting in a significant increase in protein expression and accumulation over time. …”
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  16. 2836
  17. 2837
    por Gu, Bo, Zhu, Wei-Guo
    Publicado 2012
    “…This review focuses on the necessity, characteristics and mechanisms of the crosstalk among post-translational modifications and its effects on the precise and selective behavior of p53.…”
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  18. 2838
  19. 2839
    “…In this article, we will review, in a noninclusive fashion, several recent scientific advancements in the field of translational research, with a specific focus on how they relate to infectious disease. …”
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  20. 2840
    por Kinney, Hannah C., Volpe, Joseph J.
    Publicado 2012
    “…Translational research in preterm brain injury depends upon the delineation of the human neuropathology in order that animal models faithfully reiterate it, thereby ensuring direct relevance to the human condition. …”
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