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3001por de Oliveira, Liszt Palmeira, Moura Cardinot, Themis, Nunes Carreras Del Castillo, Letícia, Cavalheiro Queiroz, Marcelo, Cavalli Polesello, Giancarlo“…METHODS: the Hip Outcome Score questionnaire was translated into Portuguese following the methodology consisting of the steps of translation, back-translation, pretesting and final translation. …”
Publicado 2014
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3002
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3003“…This would not only provide veterinary oncology access to the latest developments in medicine before they are available for clinical use in animals, but could also lead to generation of clinical data in animal patients that could be translated to humans. Nevertheless, there are several limitations to practical conduct of clinical trials in veterinary medicine. …”
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3004por Silver, Samuel A., Cardinal, Héloise, Colwell, Katelyn, Burger, Dylan, Dickhout, Jeffrey G.“…However, acute kidney injury AKI research findings have yet to be translated into significant changes in clinical practice. …”
Publicado 2015
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3005
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3006por Herr, Timothy M., Bielinski, Suzette J., Bottinger, Erwin, Brautbar, Ariel, Brilliant, Murray, Chute, Christopher G., Denny, Joshua, Freimuth, Robert R., Hartzler, Andrea, Kannry, Joseph, Kohane, Isaac S., Kullo, Iftikhar J., Lin, Simon, Pathak, Jyotishman, Peissig, Peggy, Pulley, Jill, Ralston, James, Rasmussen, Luke, Roden, Dan, Tromp, Gerard, Williams, Marc S., Starren, Justin“…Its goal is to allow informaticians, researchers, and clinicians to approach the problem of translating omic data from bench to bedside, by using discrete steps with clearly defined needs. …”
Publicado 2015
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3007“…Studies in numerous organisms highlighted the prevalence of post-transcriptional mRNA regulation, which relies on RNA-targeting factors that influence mRNA fates (e.g. decay or translational efficiency). Conserved translational repressors were identified that build negative feedback loops to ensure one or the other cell fate. …”
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3008“…METHODS: The Simple Shoulder Test was translated from English into Argentinian Spanish by two independent translators, translated back into English and evaluated for accuracy by an expert committee to correct the possible discrepancies. …”
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3009“…We aim to create a methodology for translating requirements from the error analysis framework to the modern uncertainty approach using the product level requirements of the Advanced Baseline Imager (ABI) that will fly on the Geostationary Operational Environmental Satellite R-Series (GOES-R). …”
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3010por Arciero, Robert A., Parrino, Anthony, Diaz-Doran, Vilmaris, Obopilwe, Elifho, Cote, Mark P., Mazzocca, Augustus D., Provencher, Matthew“…A MTS 858 Servohydraulic test system (MTS Systems, Eden Prairie, MN) was used to translate the humeral head anteriorly 10mm at a rate of 2.0mm/sec. …”
Publicado 2014
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3011“…During the asexual replication cycle of the malaria parasite Plasmodium falciparum, the RNA-binding protein PfAlba1 binds and stabilizes a subset of transcripts for translation at a later time point. Please see related Research article: http://www.genomebiology.com/2015/16/1/212…”
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3012por Wells, Dominic“…But how good are the mouse models and how useful are they in assessing the potential for translational medicine? In this Editorial, I will discuss current difficulties in translational research as well as examples of good laboratory practice and guidelines that are being implemented to improve the translational potential of animal studies in the field of neuromuscular rare diseases. …”
Publicado 2015
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3013“…Initiation of mRNA translation is a major checkpoint for regulating level and fidelity of protein synthesis. …”
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3014“…Since rancRNAs are associated with the arguable most central enzyme of the cell it seems plausible to propose a role in translation control. Indeed first experimental evidence on small rancRNAs has been presented, linking ribosome association with fine-tuning the rate of protein biosynthesis in a stress-dependent manner.…”
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3015Publicado 2015“…We describe here the rationale and design of the International Genetics & Translational Research in Transplantation Network. The network comprises 22 studies to date, including 16494 transplant recipients and 11669 donors, of whom more than 5000 are of non-European ancestry, all of whom have existing genomewide genotype data sets. …”
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3016
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3017
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3018
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3019por Abe, Naoko, Matsumoto, Ken, Nishihara, Mizuki, Nakano, Yukiko, Shibata, Aya, Maruyama, Hideto, Shuto, Satoshi, Matsuda, Akira, Yoshida, Minoru, Ito, Yoshihiro, Abe, Hiroshi“…We recently reported that circular RNA is efficiently translated by a rolling circle amplification (RCA) mechanism in a cell-free Escherichia coli translation system. …”
Publicado 2015
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3020