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  1. 3221
    “…During the last five years, there has been a significantly increasing interest in adult adipose stem cells (ASCs) as a suitable tool for translational medicine applications. The abundant and renewable source of ASCs and the relatively simple procedure for cell isolation are only some of the reasons for this success. …”
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    Adipose Stem Cell Translational Applications: From Bench-to-Bedside
  2. 3222
    “…To prevent ownership conflicts as well as misuse or abuse of PRO instruments, the ISOQOL Translation and Cultural Adaptation Special Interest Group (TCA-SIG) provides recommendations to authors of PRO instruments and their users. …”
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    Reflection paper on copyright, patient-reported outcome instruments and their translations
  3. 3223
    por Maurin, Thomas, Bardoni, Barbara
    Publicado 2018
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    Fragile X Mental Retardation Protein: To Be or Not to Be a Translational Enhancer
  4. 3224
    por Abdrabou, Abdalla, Wang, Zhixiang
    Publicado 2018
    “…Other modifications include RNA splicing and microRNAs; various post-translational modifications have also been shown to regulate the activity and function of Rac1. …”
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    Post-Translational Modification and Subcellular Distribution of Rac1: An Update
  5. 3225
    por McCulloch, Ryan S.
    Publicado 2018
    “…METHODS: Sixteen cyclists were recruited to pedal on three pedal systems: standard pedals (STD), free lateral translation (LAT), and a guided lateral translation pedal (VL). …”
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    Influence of lateral pedal translation on muscle recruitment and kinematics in cyclists
  6. 3226
    “…Mechanistically, we show that TOP1MT associates with mitoribosomal subunits, ensuring optimal mitochondrial translation and assembly of oxidative phosphorylation complexes that are critical for sustaining tumor growth. …”
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    The mitochondrial type IB topoisomerase drives mitochondrial translation and carcinogenesis
  7. 3227
    “…AIM: The aim of our study was to translate the Migraine Screen Questionnaire (MS-Q) to BHS (Bosnian/Croatian /Serbian) language and to test reliability and validity of the translation on a sample of primary care patients. …”
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    Translation and Transcultural Validation of Migraine Screening Questionnaire (MS-Q)
  8. 3228
    “…A key regulator of error-prone versus error-free DDT is the replication clamp, proliferating cell nuclear antigen (PCNA). Post-translational modifications (PTMs) of PCNA, mainly by ubiquitin and SUMO (small ubiquitin-like modifier), play a critical role in DDT. …”
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    Mechanisms of DNA Damage Tolerance: Post-Translational Regulation of PCNA
  9. 3229
    “…Translation can initiate at alternate, non-canonical start codons in response to stressful stimuli in mammalian cells. …”
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    Comprehensive profiling of translation initiation in influenza virus infected cells
  10. 3230
    “…Proteins with hydrophobic signal sequences are first recognized by the signal recognition particle (SRP)(3,4) and then moved co-translationally through the Sec61/SecY channel by the associated translating ribosome. …”
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    Structure of the post-translational protein translocation machinery of the ER membrane
  11. 3231
    “…Recruitment and engagement for clinical and translational research is challenging, especially among medically underserved and ethnic or racial minority populations. …”
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    A comprehensive approach to community recruitment for clinical and translational research
  12. 3232
    “…Polysome profiling is a widely used method to monitor the translation status of mRNAs. Although it is theoretically a simple technique, it is labor intensive. …”
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    Multiplexing polysome profiling experiments to study translation in Escherichia coli
  13. 3233
    por Selli, Cigdem, Sims, Andrew H
    Publicado 2019
    “…In this review, we discuss the potential and challenges of using the neoadjuvant setting in translational breast cancer research, considering the implications for improving our understanding of response to treatment, predicting therapy benefit, modelling breast cancer dormancy, and the development of drug resistance.…”
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    Neoadjuvant Therapy for Breast Cancer as a Model for Translational Research
  14. 3234
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    Translating the role of PARP inhibitors in triple-negative breast cancer
  15. 3235
    por Katoh, Takayuki, Suga, Hiroaki
    Publicado 2019
    “…In this review, we comprehensively summarize recent attempts to engineer the translation systems, resulting in a significant improvement of the incorporation of exotic amino acids.…”
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    Engineering Translation Components Improve Incorporation of Exotic Amino Acids
  16. 3236
    “…We have focused on summarizing the models critical to new drug development and described the translational features of the models that contributed to our understanding of disease pathogenesis and establishment of preclinical POC.…”
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    Translational Preclinical Pharmacologic Disease Models for Ophthalmic Drug Development
  17. 3237
    por Ringborg, Ulrik
    Publicado 2019
    “…Consequently, to increase the effectiveness of translational research, the different components of the cancer research continuum need to be better connected to the fundamental aim of a mission‐oriented approach to cancer (Celis and Pavalkis, 2017).…”
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    Translational cancer research – a coherent cancer research continuum
  18. 3238
    “…There are many barriers to translation of pharmacogenetic information to the clinic, however, in human medicine, international initiatives are promising real change in the delivery of personalized medicine by 2025. …”
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    Translating Pharmacogenetics and Pharmacogenomics to the Clinic: Progress in Human and Veterinary Medicine
  19. 3239
    “…In this review, we discuss the process of utilizing genomic sequencing approaches, gene editing technologies, and transgenic porcine cancer models to develop clinically relevant, personalized large animal cancer models for use in co-clinical trials, ultimately improving treatment stratification and translation of novel therapeutic approaches to clinical practice.…”
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    Translating Human Cancer Sequences Into Personalized Porcine Cancer Models
  20. 3240
    “…BACKGROUND: The standard genetic code is a recipe for assigning unambiguously 21 labels, i.e. amino acids and stop translation signal, to 64 codons. However, at early stages of the translational machinery development, the codons did not have to be read unambiguously and the early genetic codes could have contained some ambiguous assignments of codons to amino acids. …”
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    The influence of different types of translational inaccuracies on the genetic code structure
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