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681por Zhang, NingEnlace del recurso
Publicado 2023
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682
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683“…Post-translational modifications (PTMs) are crucial regulatory mechanisms that alter the properties of a protein by covalently attaching a modified chemical group to some of its amino acid residues. …”
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684“…By sharing knowledge and resources in a globally accessible manner, we can support human disease research to accelerate the translation of fundamental discoveries to effective treatments or diagnostics for diverse patient populations. …”
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685“…BACKGROUND: Translational GTPases are a family of proteins in which GTPase activity is stimulated by the large ribosomal subunit. …”
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686por Ruttenberg, Alan, Clark, Tim, Bug, William, Samwald, Matthias, Bodenreider, Olivier, Chen, Helen, Doherty, Donald, Forsberg, Kerstin, Gao, Yong, Kashyap, Vipul, Kinoshita, June, Luciano, Joanne, Marshall, M Scott, Ogbuji, Chimezie, Rees, Jonathan, Stephens, Susie, Wong, Gwendolyn T, Wu, Elizabeth, Zaccagnini, Davide, Hongsermeier, Tonya, Neumann, Eric, Herman, Ivan, Cheung, Kei-Hoi“…A significant barrier to translational research is the lack of uniformly structured data across related biomedical domains. …”
Publicado 2007
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687
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688por Swen, Jesse J, Huizinga, Tom W, Gelderblom, Hans, de Vries, Elisabeth G. E, Assendelft, Willem J. J, Kirchheiner, Julia, Guchelaar, Henk-JanMaterias: “…Research in Translation…”
Publicado 2007
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689
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690“…As invading viruses do not harbor functional ribosomes in their virions, successful amplification of the viral genomes requires that viral mRNAs compete with cellular mRNAs for the host cell translation apparatus. Several RNA viruses have evolved remarkable strategies to recruit the host translation initiation factors required for the first steps in translation initiation by host cell mRNAs. …”
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691por Wehling, Martin“…"Translational medicine" as a fashionable term is being increasingly used to describe the wish of biomedical researchers to ultimately help patients. …”
Publicado 2008
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693por McConnell, Patrick, Dash, Rajesh C, Chilukuri, Ram, Pietrobon, Ricardo, Johnson, Kimberly, Annechiarico, Robert, Cuticchia, A Jamie“…CONCLUSION: Currently being deployed at Duke University and a few other centers, we expect that caTRIP will make a significant contribution to further the development of translational research through the facilitation of its data exchange and storage processes.…”
Publicado 2008
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694“…It is shown, as theoretically expected, that population size has an important role in the operativity of translational selection.…”
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695por Robert, Francis, Carrier, Marilyn, Rawe, Svea, Chen, Samuel, Lowe, Scott, Pelletier, Jerry“…BACKGROUND: The process of translation occurs at a nexus point downstream of a number of signal pathways and developmental processes. …”
Publicado 2009
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696“…The AAAS has announced the launch of Science Translational Medicine. This is further and critical recognition of this discipline and we are deeply gratified that translational medicine has risen to the level of recognition by one of the world's most prestigious scientific organizations. …”
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697por Dougherty, Edward R“…The term “translational science” has recently become very popular with its usage appearing to be almost exclusively related to medicine, in particular, the “translation” of biological knowledge into medical practice. …”
Publicado 2009
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698por Butte, Atul J“…I also list four recommendations for bioinformaticians wishing to get more involved in translational research.…”
Publicado 2009
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