Materias dentro de su búsqueda.
Materias dentro de su búsqueda.
Operas
225
Historia
206
Sinfonías
106
Traducción e interpretación
82
Musical settings
75
Música para piano
69
Música
66
Música orquestal
66
Motetes
64
Música instrumental
59
Filosofía
56
Música de cámara
45
Música vocal sacra
44
Sonatas (Piano)
43
Songs and music
43
Crítica e interpretación
42
Historia y crítica
37
Oberturas
37
Misas
36
Música vocal
35
Conciertos (Piano)
34
Traducciones al inglés
33
Cuartetos de cuerda
32
Música para órgano
32
Novela rusa
32
Coros sacros (Voces mixtas) con orquesta
31
Ballets
30
Coros sacros (Voces mixtas), sin acompañamiento
30
Oratorios
30
Música Instrumental
29
-
921“…Ribosomes are evolutionary conserved ribonucleoprotein complexes that function as two separate subunits in all kingdoms. During translation initiation, the two subunits assemble to form the mature ribosome, which is responsible for translating the messenger RNA. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
922“…Iron is an essential element for all eukaryotes, since it acts as a cofactor for many enzymes involved in basic cellular functions, including translation. While the mammalian iron-regulatory protein/iron-responsive element (IRP/IRE) system arose as one of the first examples of translational regulation in higher eukaryotes, little is known about the contribution of iron itself to the different stages of eukaryotic translation. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
923por Hartl, Dominik, de Luca, Valeria, Kostikova, Anna, Laramie, Jason, Kennedy, Scott, Ferrero, Enrico, Siegel, Richard, Fink, Martin, Ahmed, Sohail, Millholland, John, Schuhmacher, Alexander, Hinder, Markus, Piali, Luca, Roth, Adrian“…This paradigm shift comes with a need for both translation and precision, leading to a modern Translational Precision Medicine approach to drug discovery and development. …”
Publicado 2021
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
924“…Mechanisms that control translation play important roles in tumor progression and metastasis. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
925“…Notably, recent studies have indicated that some circRNAs have translational functions. Internal ribosome entry sites and the N6‐methyladenosine modification mediate cap‐independent translation. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
926“…Protein asymmetry can be achieved by the transport of the protein itself or the transport of the mRNA that is then translated at target sites in neuronal processes. The latter transport mechanism implies local translation of localized mRNAs. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
927
-
928por Flenner, Frederik, Jungen, Christiane, Küpker, Nadine, Ibel, Antonia, Kruse, Martin, Koivumäki, Jussi T., Rinas, Anna, Zech, Antonia T.L., Rhoden, Alexandra, Wijnker, Paul J.M., Lemoine, Marc D., Steenpass, Anna, Girdauskas, Evaldas, Eschenhagen, Thomas, Meyer, Christian, van der Velden, Jolanda, Patten-Hamel, Monica, Christ, Torsten, Carrier, Lucie“…In this study, we explored arrhythmia mechanisms in mice carrying a HCM mutation in Mybpc3 (Mybpc3-KI) and tested the translatability of our findings in human engineered heart tissues (EHTs) derived from CRISPR/Cas9-generated homozygous MYBPC3 mutant (MYBPC3hom) in induced pluripotent stem cells (iPSC) and to left ventricular septum samples obtained from HCM patients. …”
Publicado 2021
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
929“…Ribosome stalling during translation significantly reduces cell viability, because cells have to spend resources on the synthesis of new ribosomes. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
930“…Post-translational modifications (PTM) involve enzyme-mediated covalent addition of functional groups to proteins during or after synthesis. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
931“…Their consequences for translation fidelity are not always well documented. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
932por Chalkiadaki, Kleanthi, Statoulla, Elpida, Markou, Maria, Bellou, Sofia, Bagli, Eleni, Fotsis, Theodore, Murphy, Carol, Gkogkas, Christos G.“…Herein, we will review mechanisms of translational control relevant to brain development in neurons and ECs in health and disease.…”
Publicado 2021
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
933
-
934por del Toro, Neylen, Lessard, Frédéric, Bouchard, Jacob, Mobasheri, Nasrin, Guillon, Jordan, Igelmann, Sebastian, Tardif, Sarah, Buffard, Tony, Bourdeau, Véronique, Brakier-Gingras, Léa, Ferbeyre, Gerardo“…The origin and evolution of cancer cells is considered to be mainly fueled by DNA mutations. Although translation errors could also expand the cellular proteome, their role in cancer biology remains poorly understood. …”
Publicado 2021
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
935“…Recent work has shown that oxidative post-translational modification by reactive oxygen (ROS) or nitrogen (RNS) species results in inhibition of sirtuin deacylase activity through cysteine nitrosation, glutathionylation, sulfenylation, and sulfhydration as well as tyrosine nitration. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
936
-
937
-
938“…We enlist and discuss findings of the recent works that use broad profiling-type approaches to investigate the age-related translational pathways. We outline the limitations of the methods and the remaining unknowns in the established ageing-associated translation mechanisms, and flag translational mechanisms with high prospective importance in ageing, for future studies.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
939“…In particular, we discussed the close link between translational factors and human diseases, and clarified how post-translational modifications control the activity of translational factors in tumors.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
940“…Additionally, we describe what is known about the translational machinery within all these diseases. Distinct eukaryotic translation initiation factors (eIFs) with specific functional roles and aberrant expression in HCC are reported. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto