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981
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982“…Extant biology uses RNA to record genetic information and proteins to execute biochemical functions. Nucleotides are translated into amino acids via transfer RNA in the central dogma. tRNA is essential in translation as it connects the codon and the cognate amino acid. …”
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983“…RESULTS: Noting the need for a general principle to be interpreted, adapted and translated in order to be rendered meaningful at a local level, we studied precisely these multiple territorial translations of RRI, the organizational and institutional orderings with which they co-emerge and the challenges that come with these translations. …”
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984
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985
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986“…Mitochondrial ribosomes are specialized to translate the 13 membrane proteins encoded in the mitochondrial genome, which shapes the oxidative phosphorylation complexes essential for cellular energy metabolism. …”
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987por von der Haar, Tobias, Mulroney, Thomas E., Hedayioglu, Fabio, Kurusamy, Sathishkumar, Rust, Maria, Lilley, Kathryn S., Thaventhiran, James E., Willis, Anne E., Smales, C. Mark“…In vitro transcribed, modified messenger RNAs (IVTmRNAs) have been used to vaccinate billions of individuals against the SARS-CoV-2 virus, and are currently being developed for many additional therapeutic applications. IVTmRNAs must be translated into proteins with therapeutic activity by the same cellular machinery that also translates native endogenous transcripts. …”
Publicado 2023
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988“…The rate and accuracy of translation hinges upon multiple components – including transfer RNA (tRNA) pools, tRNA modifying enzymes, and rRNA molecules – many of which are redundant in terms of gene copy number or function. …”
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989
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990“…Several studies have demonstrated improved plant resistance to various stresses through modulation of protein translation regulation, which requires a deep understanding of translational control in response to environmental stresses. …”
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991“…Numerous cellular proteins are post-translationally modified by addition of a lipid group to their structure, which dynamically influences the proteome by increasing hydrophobicity of proteins often impacting protein conformation, localization, stability, and binding affinity. …”
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992“…Cytoplasmic poly(A)-binding protein (PABPC; Pab1 in yeast) is thought to be involved in multiple steps of post-transcriptional control, including translation initiation, translation termination, and mRNA decay. …”
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993por Trendel, Jakob, Boileau, Etienne, Jochem, Marco, Dieterich, Christoph, Krijgsveld, Jeroen“…We use quantitative proteomics to demonstrate that translation of these mRNAs remains repressed during the initial hours of recovery after arsenite stress. …”
Publicado 2023
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994por Chen, Xiaoming, Andersson, Roland, Cho, William CS, Christiani, David, Coico, Richard, Drazen, Jeffery, Ege, Markus, Fehniger, Thomas, Gao, Hongwei, Jin, Kunlin, Liebman, Michael N, Lopez, Elena, Marraro, Giuseppe, Marko-Varga, Gyorgy, Marincola, Francesco M, Popescu, Laurentiu M, Spada, Claudio, Shahzad, Aamir, Wang, Ena, Wang, Wei, Wang, Xiangdong, Wang, Yong-Xiao, Xia, Jinglin, Qu, Jia“…BACKGROUND: Supported by the International Society for Translational Medicine (ISTM), Wenzhou Medical College and the First Affiliated Hospital of Wenzhou Medical College, the International Conference on Translational Medicine (ICTM) was held on October 22–23, 2011 in Wenzhou, China. …”
Publicado 2012
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995por Kelley, Maureen, Edwards, Kelly, Starks, Helene, Fullerton, Stephanie M., James, Rosalina, Goering, Sara, Holland, Suzanne, Disis, Mary L., Burke, Wylie“…The speed and effectiveness of current approaches to research translation are widely viewed as disappointing given small gains in real population health outcomes despite huge investments in basic and translational science. …”
Publicado 2012
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996
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997“…Despite its ability to bind to 40S subunits independently, the HCV 3′UTR only stimulates translation in cis, without affecting the first round translation rate. …”
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998por Arbini, A A, Guerra, F, Greco, M, Marra, E, Gandee, L, Xiao, G, Lotan, Y, Gasparre, G, Hsieh, J-T, Moro, LEnlace del recurso
Publicado 2013
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999por Bærøe, Kristine“…In this paper, I take up Cribb’s invitation and discuss further analytic distinctions needed to base an ethics aiming to translate between theory and practice. DISCUSSION: The analytic distinctions needed to base an ethics aiming to translate between theory and practice are identified as ‘movements of translation’. …”
Publicado 2014
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1000por Buchholz, Susan Weber, Sandi, Giselle, Ingram, Diana, Welch, Mary Jane, Ocampo, Edith V“…METHODS: The consent form and study documents, including the existing English physical activity text messages, were translated from English into Spanish, and received translation certification as well as Institutional Review Board approval. …”
Publicado 2015
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