“…During translation, consecutive ribosomes load on an mRNA and form a polysome. …”
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“…Translation dysregulation also contributes to cancer development, though relatively little is known about the changes that occur to the translational system in cancer. …”
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“…INSPIRES is an international symposium on translational research in lung injury as well as in other areas of critical illness, intended to serve as a platform for the translational biology working group. …”
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Materias: “…Basic/Translational Science/Team Science…”
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“…Translational research is defined as the effort to traverse a particular step of the translation process for a particular target or disease. …”
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“…We found that circYap could bind with Yap mRNA and the translation initiation associated proteins, eIF4G and PABP. …”
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“…In contrast, the translational landscape in Archaea remains mostly unexplored. …”
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“…Here, we summarize recent evidence on how ribosome pausing affects translational efficiency and protein folding. We discuss the factors that slow down translation elongation and affect the quality of the newly synthesized protein. …”
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“…First, an internal ribosome entry site (IRES) enables cap-independent translation. The second regulon is a translation inhibitory element or TIE, which ensures concomitant cap-dependent translation inhibition. …”
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“…BACKGROUND: Knowledge translation (KT) has emerged as an important consideration to reduce knowledge-to-practice gaps in healthcare settings. …”
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“…Background: Machine translation (MT) technologies have increasing applications in healthcare. …”
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“…The model uses two stacks of transformers in an encoder-decoder architecture, a setup similar to the neural networks used in state-of-the-art machine translation. Unlike neural machine translation, which usually tokenizes input and output into words or sub-words, our model processes the InChI and predicts the IUPAC name character by character. …”
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“…During SARS-CoV-2 proliferation, the translation of viral RNAs is usually the rate-limiting step. …”
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“…OBJECTIVES/GOALS: The goal of this study is to highlight the unique characteristics of Miami CTSIs Master of Science in Clinical and Translational Investigation (MSCTI) as part of CTSIs overall translational workforce development program and to describe program outcomes. …”
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“…PKR binding to IRES stem-loop domains 5–6 led to dimerization and autoactivation, displaced host translation initiation factors, and suppressed viral protein synthesis. …”
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“…This study shows that, to understand the effect of task complexity on translation process and its end product, performance in translation tasks of various complexity levels needs to be compared in a specific setting, in which more factors are considered besides task complexity—especially students’ translating self-efficacy belief (TSEB). …”
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“…These solutions to translational workforce development can be implemented to address future public health emergencies.…”
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“…Forward-looking and adaptive decision-making structures are those that prioritize sustained relationships, mutual trust and commitment, ongoing communication, proactive identification of community concerns and needs, shared goals and decision making, as well as ample appreciation of community members and their contributions to translational research. There is a strong need for further community-engaged research and workforce training on how to build our collective and individual adaptive capacity to sustain and improve processes and outcomes of engagement with and by communities—in all aspects of translational science.…”
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“…Furthermore, the results also indicate that growth translation mindsets positively influence students’ attitudes towards the effectiveness of translation technology, teacher influence, exhibition to translation technology, and mindfulness about translation technology, whereas fixed translation mindsets only negatively predict students’ teacher influence. …”
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