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“…In the case of translational noncrystallographic symmetry (tNCS), two or more copies of a component in the asymmetric unit of the crystal are present in a similar orientation. …”
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“…CONTRIBUTING REVIEWERS: The editor of Journal of Translational Medicine would like to thank all our reviewers who have contributed to the journal in Volume 10 (2012).…”
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“…We also outline our vision that cloud computing could be an enabling tool to facilitate translational bioinformatics research.…”
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“…Medical researchers have called for new forms of translational science that can solve complex medical problems. …”
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“…Text mining for translational bioinformatics is a new field with tremendous research potential. …”
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“…BACKGROUND: The National Institutes of Health (NIH) Roadmap places special emphasis on “bench-to-bedside” research, or the “translation” of basic science research into practical clinical applications. …”
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“…This mini-review summarizes recent advances in our clinical understanding of Pneumocystis and PcP, describes ongoing areas of clinical and translational research, and offers recommendations for future clinical research from researchers participating in the “First centenary of the Pneumocystis discovery”.…”
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“…We leverage these data to parameterize a computational model of translation, keeping track of every ribosome, tRNA, and mRNA molecule in a yeast cell. …”
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“…Most of the randomly chosen alternative sets of codons scored weaker associations than the actual sets of preferred codons, suggesting that codon position within plant genes and codon usage bias have coevolved to maximize translational accuracy. All these findings are consistent with the mistranslation-induced protein misfolding theory, which predicts the natural selection of highly preferred codons more frequently at sites where translation errors could compromise protein folding or functionality. …”
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“…Conclusion: The findings point to translational direction as a novel functional probe to help understand the underlying neural mechanisms of wider cognitive dysfunction in schizophrenia.…”
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“…But translation is also inhibited by a science policy environment with its own impediments. …”
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“…The dispute is about potential public policy development, rather than on science translation and research opportunities and priorities. …”
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“…So far, preclinical and translational research on PSD is largely lacking. The implementation and characterization of suitable animal models is clearly a major prerequisite for deeper insights into the biological basis of post-stroke mood disturbances. …”
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“…In this overview, the rationale and supporting data for pursuing neuroprotective strategies and clinical translation in the three components of the CNS (brain, spinal cord and eye) are described. …”
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