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  1. 143861
    “…BACKGROUND: People with long-term conditions frequently transition between care settings that require information about a patient’s medicines to be transferred or translated between systems. This process is currently error prone and associated with unintentional changes to medications and miscommunication, which can lead to serious patient consequences. …”
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    Barriers and Opportunities for the Use of Digital Tools in Medicines Optimization Across the Interfaces of Care: Stakeholder Interviews in the United Kingdom
  2. 143862
    “…The success of ATRA in APL, however, remains to be translated to non-APL acute myeloid leukemia (AML). …”
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    Dual inhibition of EZH2 and G9A/GLP histone methyltransferases by HKMTI-1-005 promotes differentiation of acute myeloid leukemia cells
  3. 143863
    “…These findings reflect the complexities of the immune escape mechanisms of EBV, which may interfere with the CAR-T cell property and potency and should be taken into account for future clinical translation.…”
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    Non-viral TRAC-knocked-in CD19(KI)CAR-T and gp350(KI)CAR-T cells tested against Burkitt lymphomas with type 1 or 2 EBV infection: In vivo cellular dynamics and potency
  4. 143864
    “…We identified an elevated integrated stress response (ISR) characterized by phosphorylation of eIF2α as a relevant molecular mechanism which is able to affect translation of myelin proteins. CONCLUSIONS: Our findings demonstrate an essential role of IKK/NF-κB signaling in mature, post-mitotic OLs in regulating stress-induced senescence in these cells. …”
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    NF-κB is a critical mediator of post-mitotic senescence in oligodendrocytes and subsequent white matter loss
  5. 143865
    “…The superiority design of CYPRO will allow deriving explicit recommendations on endurance training design in pwPPMS that can be readily translated into clinical practice. TRIAL REGISTRATION: CYPRO has been prospectively registered at ClinicalTrials.gov on 8 February 2022 (NCT05229861). …”
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    Cycling in primary progressive multiple sclerosis (CYPRO): study protocol for a randomized controlled superiority trial evaluating the effects of high-intensity interval training in persons with primary progressive multiple sclerosis
  6. 143866
    “…We corroborate the functionality of the peripheral clock directly in the organs of translational models, inaccessible in human participants. …”
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    The circadian clock remains intact, but with dampened hormonal output in heart failure
  7. 143867
    “…Compared to a propensity score–matched cohort, DHI users demonstrated approximately US $10 per user per month lower average medical spending (P=.02) with a concomitant increase in preventive care activities and decrease in nonemergent emergency department admissions. These savings translated to approximately US $6.8 million in avoidable health care costs over the course of 1 year. …”
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    The Influence of a Wearable-Based Reward Program on Health Care Costs: Retrospective, Propensity Score–Matched Cohort Study
  8. 143868
    por Argyropoulos, Christos D, Leckler, Janina, Salmanton-García, Jon, Constantinou, Marinos, Alexandrou, Alexandra, Themistocleous, Sophia, Noula, Evgenia, Shiamakkides, George, Nearchou, Andria, Stewart, Fiona A, Albus, Kerstin, Koniordou, Markela, Kopsidas, Ioannis, Spivak, Orly, Hellemans, Margot, Hendrickx, Greet, Davis, Ruth Joanna, Azzini, Anna Maria, Simon, Paula Valle, Carcas-Sansuan, Antonio Javier, Askling, Helena Hervius, Vene, Sirkka, Prellezo, Jana Baranda, Álvarez-Barco, Elena, Macken, Alan J, Di Marzo, Romina, Luís, Catarina, Olesen, Ole F, Frias Iniesta, Jesus A, Barta, Imre, Tóth, Krisztina, Akova, Murat, Bonten, Marc M J, Cohen-Kandli, Miriam, Cox, Rebecca Jane, Součková, Lenka, Husa, Petr, Jancoriene, Ligita, Launay, Odile, Lundgren, Jens, Mallon, Patrick, Armeftis, Charis, Marques, Laura, Naucler, Pontus, Ochando, Jordi, Tacconelli, Evelina, van Damme, Pierre, Zaoutis, Theoklis, Hofstraat, Sanne, Bruijning-Verhagen, Patricia, Zeitlinger, Markus, Cornely, Oliver A, Pana, Zoi Dorothea
    Publicado 2023
    “…This material has been translated into several languages and is intended to be freely and easily accessible to facilitate dissemination among VACCELERATE network participant countries and the European and global scientific, industrial, and public community. …”
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    Enhancing Public Health Communication Regarding Vaccine Trials: Design and Development of the Pan-European VACCELERATE Toolkit
  9. 143869
    “…The study’s findings will be translated into key factors that could support designing future health care services utilizing evidence-based practice. …”
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    Identification of Key Factors for Optimized Health Care Services: Protocol for a Multiphase Study of the Dubai Vaccination Campaign
  10. 143870
    “…Even a slight increase of 10 μg/m(3) in PM(2.5) can translate to a 5.4% increase in VAP incidence (95% CI: 1.4%-9.5%) while the VAP incidence increased to 11.1% (95%CI: 4.5–19.5%) when PM(2.5) concentration is well below the National Ambient Air Quality standard (NAAQS) of 50 μg/m(3). …”
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    Short-term exposure to ambient fine particulate pollution aggravates ventilator-associated pneumonia in pediatric intensive care patients undergoing cardiovascular surgeries
  11. 143871
    “…Despite the fact that a deeper understanding of the immune dysfunction caused by chronic SCI is still required, the characterization of circulating leukocytes such as Tregs and other populations can open up the possibility of finding translational biomarkers or therapeutic approaches that may aid in the clinical management of chronic SCI. …”
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    Abnormal Characterization and Distribution of Circulating Regulatory T Cells in Patients with Chronic Spinal Cord Injury According to the Period of Evolution
  12. 143872
    “…All interviews were conducted in Kinyarwanda and later translated into English. Data were analyzed using qualitative content analysis. …”
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    Women leaders perceived barriers and consequences of safe abortion in Rwanda: a qualitative study
  13. 143873
    “…Only studies published between 1999 and 2022, in English, or in English translation, were included. The quality of evidence was assessed using the Newcastle-Ottawa Scale (NOS). …”
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    Sex differences and the effect of female sex hormones on auditory function: a systematic review
  14. 143874
    “…Prototype development was guided by co-design principles and strategies, and tool content was informed by a previous needs assessment led by our team, the autistic collaborators’ lived experiences, considering intersectionality, research on knowledge translation (KT) tool development, and recommendations from the International Patient Decision Aid Standards. …”
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    Development and Usability Testing of a Web-Based Workplace Disability Disclosure Decision Aid Tool for Autistic Youth and Young Adults: Qualitative Co-design Study
  15. 143875
    “…All studies showed a significant improvement in posterior translation, from 11.5 ± 1.2 mm to 3.3 ± 1.1 mm, using radiography (side-to-side difference). …”
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    Good clinical and radiological results following remnant-preserving posterior cruciate ligament reconstruction: a systematic review
  16. 143876
    “…Early identification of such complications may help in timely institution of therapeutic measures and translate into improved prognosis. OBJECTIVE: The objective of this study was to evaluate the role of procalcitonin in early prediction of the adverse events after surgery in patients of esophageal atresia and the temporal relationship with clinical manifestations and other inflammatory biomarkers such as C-reactive protein (CRP). …”
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    Role of Procalcitonin as a Biomarker in Early Identification of Adverse Events Following Esophageal Atresia Surgery
  17. 143877
    “…RESULTS: Hospital administration approved our daily burn clinic in July of 2020 allowing for improved outpatient dressing and wound management, easy access to quality burn rehabilitation, translating to decreased length of stay. Communication was sent to all area emergency rooms, urgent cares, pediatrician offices and primary care offices to inform them of the increased availability of the burn clinic. …”
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    534 If You Build It, They Will Come: Everyday Burn Clinic Enhanced Access to Care
  18. 143878
    “…The qualitative data were recorded using tape recorder, transcribed in Amharic and translated to English language. Thematic analysis was done to supplement the quantitative findings. …”
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    Comprehensive emergency management of obstetric and newborn care program implementation at University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia, 2021: an evaluation study
  19. 143879
    “…Non-melanoma and non-renal cell cancer was associated with a higher chance of LPFS in comparison to other cancer. A GTV > 1.5 cm³ translated into a higher risk of death compared to a GTV ≤ 1.5 cm³ and Karnofsky performance score was predictive of OS. …”
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    Fractionated stereotactic radiotherapy of brain metastases: results of a retrospective study
  20. 143880
    “…In individuals with NDD, however, such testing has not been used so far, resulting in a gap in translating preclinical results to clinical practice. …”
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    Long-term Memory Testing in Children With Typical Development and Neurodevelopmental Disorders: Remote Web-based Image Task Feasibility Study
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