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144401“…Transcription of the recombinant Kiss1 allele yields a bicistronic messenger RNA, from which both kisspeptin and rtTA are independently translated. The second mouse line, TRE-Cre mice, was constructed to express Cre recombinase under control of the PTRE3G promoter. …”
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144402por Peng, Jianhua, Volbers, Bastian, Sprügel, Maximilian I., Hoelter, Philip, Engelhorn, Tobias, Jiang, Yong, Kuramatsu, Joji B., Huttner, Hagen B., Dörfler, Arnd, Schwab, Stefan, Gerner, Stefan T.“…However, this observation did not translate into improved survival or functional outcome at 3 and 12 months.…”
Publicado 2021
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144403por Chen, Wei-Kang, Wu, Zhi-Gang, Xiao, Yun-Bei, Wang, Qin-Quan, Yu, Dong-Dong, Cai, Jian, Zhou, Chao-Feng“…Our findings provide more information for clinical therapeutic intervention and translational study designs.…”
Publicado 2021
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144404por Wright-Chisem, Joshua, Cohn, Matthew R., Yang, JaeWon, Osei, Daniel, Kogan, Monica“…Although medical students who participated in a research gap year typically enter residency with more research experience than their counterparts, it is unknown whether this translates to increased research productivity during residency compared with their peers. …”
Publicado 2021
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144405por Niles, Meredith T., Wirkkala, Kristen Brassard, Belarmino, Emily H., Bertmann, Farryl“…However, HFP for food insecure households does not translate into the same higher fruit and vegetable intake as found among food secure HFP households, suggesting this population may be trying to maintain intake, or that they may have potential important resource or technical assistance needs. …”
Publicado 2021
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144406“…Policy makers may have limited knowledge on the evidence and potential of using technology in this field, highlighting the value for knowledge translation and collaborative initiatives among policy makers and researchers. …”
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144407por Pirovano, Giacomo, Ordonez, Alvaro A., Jain, Sanjay K., Reiner, Thomas, Carroll, Laurence S., Pillarsetty, Naga Vara Kishore“…Here, we present an accurate, inexpensive, scalable, portable, and rapid detection kit to directly detect SARS-CoV-2 in biological samples that could even be translated for population testing. We have demonstrated that our method can reliably identify viral load and could be used to reach those fractions of the population with limited access to more sophisticated and expensive tests. …”
Publicado 2021
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144408por Ren, Sen, Xiong, Hewei, Chen, Jing, Yang, Xiaofan, Liu, Yutian, Guo, Jiahe, Jiang, Tao, Xu, Zhao, Yuan, Meng, Liu, Yang, Zhou, Nan, Chen, Hongrui, Li, Wenqing, Machens, Hans-Günther, Chen, Zhenbing“…BACKGROUND: Mesenchymal stem cells including adipose-derived stem cells (ASCs) have a considerable potential in the field of translational medicine. Unfortunately, multiple factors (e.g., older age, co-existing diabetes, and obesity) may impair cellular function, which hinders the overall effectiveness of autologous stem cell therapy. …”
Publicado 2021
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144409por Alsterda, Andrew, Asha, Kumari, Powrozek, Olivia, Repak, Miroslava, Goswami, Sudeshna, Dunn, Alexandra M., Memmel, Heidi C., Sharma-Walia, Neelam“…The endoplasmic reticulum (ER) regulates protein folding, post-translational modifications, lipid synthesis, and calcium signaling to attenuate the accumulation of misfolded proteins causing ER stress and maintains cellular homeostasis. …”
Publicado 2021
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144410por Pathak, Laura Elizabeth, Aguilera, Adrian, Williams, Joseph Jay, Lyles, Courtney Rees, Hernandez-Ramos, Rosa, Miramontes, Jose, Cemballi, Anupama Gunshekar, Figueroa, Caroline Astrid“…All messages were written at a sixth-grade or lower reading level and culturally adapted and translated into neutral Spanish by bilingual research staff. …”
Publicado 2021
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144411por Moraru, Manuela, Perez-Portilla, Adriana, Al-Akioui Sanz, Karima, Blazquez-Moreno, Alfonso, Arnaiz-Villena, Antonio, Reyburn, Hugh T., Vilches, Carlos“…Furthermore, we found a high frequency of two strong-phagocytosis variants: the FCGR3B-NA1 haplotype and the CNR1 duplication, which translates into an increased FCGR3B and FCGR2C copy-number. …”
Publicado 2021
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144412por Elsharkawy, Mohamed, Sharafeldeen, Ahmed, Taher, Fatma, Shalaby, Ahmed, Soliman, Ahmed, Mahmoud, Ali, Ghazal, Mohammed, Khalil, Ashraf, Alghamdi, Norah Saleh, Razek, Ahmed Abdel Khalek Abdel, Alnaghy, Eman, El-Melegy, Moumen T., Sandhu, Harpal Singh, Giridharan, Guruprasad A., El-Baz, Ayman“…The CAD system processes chest X-ray data and provides accurate, objective imaging markers to assist in the determination of patients with a higher risk of death and thus are more likely to require mechanical ventilation and/or more intensive clinical care.To obtain an accurate stochastic model that has the ability to detect the severity of lung infection, we develop a second-order Markov-Gibbs random field (MGRF) invariant under rigid transformation (translation or rotation of the image) as well as scale (i.e., pixel size). …”
Publicado 2021
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144413“…The increased popularity of the bikini-physique competitions has not translated to greater research identifying the influence of age on adaptations during contest preparation. …”
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144414“…In addition, eukaryotic translation initiation factor 4E (eIF4E) was the target gene of miR-768-3p in breast cancer. …”
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144415por Moore, Kevin, O'Shea, Emma, Kenny, Lorna, Barton, John, Tedesco, Salvatore, Sica, Marco, Crowe, Colum, Alamäki, Antti, Condell, Joan, Nordström, Anna, Timmons, Suzanne“…We extracted themes from primary studies, identified key concepts, and applied reciprocal and refutational translation techniques; findings were synthesized into third-order interpretations, and finally, a “line-of-argument” was developed. …”
Publicado 2021
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144416por Shan, Zhao, Li, Leike, Atkins, Constance Lynn, Wang, Meng, Wen, Yankai, Jeong, Jongmin, Moreno, Nicolas F, Feng, Dechun, Gui, Xun, Zhang, Ningyan, Lee, Chun Geun, Elias, Jack A, Lee, William M, Gao, Bin, Lam, Fong Wilson, An, Zhiqiang, Ju, Cynthia“…CJ received funding from NIH (DK122708, DK109574, DK121330, and DK122796) and support from a University of Texas System Translational STARs award. Portions of this work were supported with resources and the use of facilities of the Michael E. …”
Publicado 2021
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144417“…These results suggest that excitatory effects induced by anodal stimulation do not hold for every stimulation intensity, information that should be taken into consideration when translating tDCS use from the realm of research into more optimal neurorehabilitation. …”
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144418por Martinez Hernandez, Ana, Silbern, Ivan, Geffers, Insa, Tatenhorst, Lars, Becker, Stefan, Urlaub, Henning, Zweckstetter, Markus, Griesinger, Christian, Eichele, Gregor“…Neurotoxic αSyn species are broadly modified post-translationally and, in patients with genetic forms of PD, carry genetically encoded amino acid substitutions. …”
Publicado 2021
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144419por Ghanbari-Homaie, Solmaz, Meedya, Shahla, Mohammad-Alizadeh-Charandabi, Sakineh, Jafarabadi, Mohammad Asghari, Mohammadi, Eesa, Mirghafourvand, Mojgan“…However, further studies are required to translate the recommendations into practice and identify enablers and barriers during the implementation of the proposed guideline. …”
Publicado 2021
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144420“…HbA1c levels pre- and post-lockdown were respectively 7.7% (7.1, 8.4) and 7.4% (6.8, 8.2), translating into a significant reduction of − 0.1% (− 0.6, 0.15) (p < 0.0001). …”
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