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  1. 144441
    “…RESULTS: We present Translational Genomics platform for Tuberculosis (GenTB), a free and open web-based application to predict antibiotic resistance from next-generation sequence data. …”
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    GenTB: A user-friendly genome-based predictor for tuberculosis resistance powered by machine learning
  2. 144442
    “…CONCLUSION: It can be concluded that XOS can enhance cecal fermentation, while xylanase can increase the body weight gain along with the fermentation metabolites in the ceca of broilers fed the corn-SBM-based diet but the effects may not always translate into an improved mucosal absorptive capacity and a better feed efficiency. …”
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    Effects of supplemental xylanase and xylooligosaccharides on production performance and gut health variables of broiler chickens
  3. 144443
    “…BACKGROUND: Given the key role of methionine (Met) in biological processes like protein translation, methylation, and antioxidant defense, inadequate Met supply can limit performance. …”
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    Expression of proposed methionine transporters along the gastrointestinal tract of pigs and their regulation by dietary methionine sources
  4. 144444
    “…CONCLUSIONS: Taken together, the data indicated that the combination of HPV16 E6/E7-expressing DNA, NRas(G12V) DNA and DNA encoding sleeping beauty transposase is able to generate spontaneous oral tumor in HLA-A2 (AAD) transgenic mice, which can be successfully controlled by treatment with CRT/E7(N53S) DNA vaccine. The translational potential of our studies are discussed. …”
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    Control of Spontaneous HPV16 E6/E7 Expressing Oral Cancer in HLA-A2 (AAD) Transgenic Mice with Therapeutic HPV DNA Vaccine
  5. 144445
    “…The recombinant human MG53 (rhMG53) protein can enter the NSCLC cells to induce nuclear translation of G3BP2 and block arsenic trioxide-induced SG formation. …”
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    MG53 suppresses tumor progression and stress granule formation by modulating G3BP2 activity in non-small cell lung cancer
  6. 144446
    “…FUNDING: This work was supported by the National Institute for Health Research (NIHR) Imperial Patient Safety Translational Research Centre via an NIHR programme grant. …”
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    Detecting signs of deterioration in young patients with serious mental illness: a systematic review
  7. 144447
    “…Bioinformatics analysis using antiSMASH 5.0 predicted the presence of eight biosynthetic gene clusters (BGCs) encoding for the synthesis of ribosomally synthesized post-translationally modified peptides (RiPPs) and non-ribosomal peptides (NRPs) in four genomes. …”
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    Culture and genome-based analysis of four soil Clostridium isolates reveal their potential for antimicrobial production
  8. 144448
    “…Finally, this uncertainty bound is provided to a robust tube model predictive controller, which provides tube-based robustness guarantees on the system’s ability to follow the reference trajectory translationally. The combination and interfaces of these methods are shown, and some of the practical implications of their use on a planned demonstration on NASA’s Astrobee free-flyer are additionally discussed. …”
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    A Robust Observation, Planning, and Control Pipeline for Autonomous Rendezvous with Tumbling Targets
  9. 144449
    “…Future research is required to explore the translation of this digital health approach for the VTR of FHWs and its impact across low-resource settings to ameliorate the financial and time costs of training and support high-quality MNCH care delivery. …”
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    Acceptability and Potential Effectiveness of eHealth Tools for Training Primary Health Workers From Nigeria at Scale: Mixed Methods, Uncontrolled Before-and-After Study
  10. 144450
    “…Importantly, delivering CBC through an inhaler device is a translational model supporting the feasibility of trial with human subjects, authorizing further research.…”
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    A potential role for cannabichromene in modulating TRP channels during acute respiratory distress syndrome
  11. 144451
    por Negeri, Zelalem F, Levis, Brooke, Sun, Ying, He, Chen, Krishnan, Ankur, Wu, Yin, Bhandari, Parash Mani, Neupane, Dipika, Brehaut, Eliana, Benedetti, Andrea, Thombs, Brett D, Imran, Mahrukh, Rice, Danielle B, Riehm, Kira E, Azar, Marleine, Levis, Alexander W, Boruff, Jill T, Cuijpers, Pim, Gilbody, Simon, Ioannidis, John P A, Kloda, Lorie A, Patten, Scott B, Shrier, Ian, Ziegelstein, Roy C, Markham, Sarah, Alamri, Sultan H, Amtmann, Dagmar, Arroll, Bruce, Ayalon, Liat, Baradaran, Hamid R, Beraldi, Anna, Bernstein, Charles N, Bhana, Arvin, Bombardier, Charles H, Buji, Ryna Imma, Butterworth, Peter, Carter, Gregory, Chagas, Marcos H, Chan, Juliana C N, Chan, Lai Fong, Chibanda, Dixon, Clover, Kerrie, Conway, Aaron, Conwell, Yeates, Daray, Federico M, de Man-van Ginkel, Janneke M, Delgadillo, Jaime, Diez-Quevedo, Crisanto, Fann, Jesse R, Fischer, Felix H, Field, Sally, Fisher, Jane R W, Fung, Daniel, Garman, Emily C, Gelaye, Bizu, Gholizadeh, Leila, Gibson, Lorna J, Goodyear-Smith, Felicity, Green, Eric P, Greeno, Catherine G, Hall, Brian J, Hantsoo, Liisa, Haroz, Emily E, Härter, Martin, Hegerl, Ulrich, Hides, Leanne, Hobfoll, Stevan E, Honikman, Simone, Hudson, Marie, Hyphantis, Thomas, Inagaki, Masatoshi, Jeon, Hong Jin, Jetté, Nathalie, Khamseh, Mohammad E, Kӧhler, Sebastian, Kohrt, Brandon A, Kwan, Yunxin, Lamers, Femke, Lara, Maria Asunción, Levin-Aspenson, Holly F, Liu, Shen-Ing, Lotrakul, Manote, Loureiro, Sonia R, Löwe, Bernd, Luitel, Nagendra P, Lund, Crick, Marrie, Ruth Ann, Marsh, Laura, Marx, Brian P, McGuire, Anthony, Mohd Sidik, Sherina, Munhoz, Tiago N, Muramatsu, Kumiko, Nakku, Juliet E M, Navarrete, Laura, Osório, Flávia L, Pence, Brian W, Persoons, Philippe, Petersen, Inge, Picardi, Angelo, Pugh, Stephanie L, Quinn, Terence J, Rancans, Elmars, Rathod, Sujit D, Reuter, Katrin, Rooney, Alasdair G, Rowe, Heather J, Santos, Iná S, Schram, Miranda T, Shaaban, Juwita, Shinn, Eileen H, Sidebottom, Abbey, Simning, Adam, Spangenberg, Lena, Stafford, Lesley, Sung, Sharon C, Suzuki, Keiko, Tan,, Pei Lin Lynnette, Taylor-Rowan, Martin, Tran, Thach D, Turner, Alyna, van der Feltz-Cornelis, Christina M, van Heyningen, Thandi, van Weert, Henk C, Vöhringer, Paul A, Wagner, Lynne I, Wang, Jian Li, Wang, Wenzheng, Watson, David, White, Jennifer, Whooley, Mary A, Winkley, Kirsty, Wynter, Karen, Yamada, Mitsuhiko, Zeng, Qing Zhi, Zhang, Yuying
    Publicado 2021
    “…CONCLUSIONS: Researchers and clinicians could use results to determine outcomes, such as total number of positive screens and false positive screens, at different PHQ-9 cut-off values for different clinical settings using the knowledge translation tool at www.depressionscreening100.com/phq. …”
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    Accuracy of the Patient Health Questionnaire-9 for screening to detect major depression: updated systematic review and individual participant data meta-analysis
  12. 144452
    “…Results of this study provide a framework for understanding the clonal behavior of human HPSC repopulating in a mouse environment, critical for translating results from humanized mice models to the human settings. …”
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    Longitudinal clonal tracking in humanized mice reveals sustained polyclonal repopulation of gene-modified human-HSPC despite vector integration bias
  13. 144453
    “…The String Analyses showed that the miR-1260a was associated with the ribosomal protein family which was known to be effective in the translation stage of cell and that miR-1260b was associated with CHEK2 protein which was a member of the serine/threonine-protein kinase family. …”
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    High expression level of miR-1260 family in the peripheral blood of patients with ovarian carcinoma
  14. 144454
    “…Through the fatty acid acylation process, this enzyme orchestrates post-translational modifications to proteins involved in cell development and differentiation. …”
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    A small molecule modulating monounsaturated fatty acids and Wnt signaling confers maintenance to induced pluripotent stem cells against endodermal differentiation
  15. 144455
    “…BACKGROUND: The web-based BeUpstanding program supports desk workers to sit less and move more. Successfully translated from a research-delivered intervention, BeUpstanding has gone through iterative development and evaluation phases in preparation for wide-scale implementation. …”
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    A RE-AIM evaluation in early adopters to iteratively improve the online BeUpstanding™ program supporting workers to sit less and move more
  16. 144456
    “…RESULTS: ER stress markers, e.g., eukaryotic translation initiation factor 2α (eIF2α), activating transcription factor 4 (ATF4), and C/EBP homologous protein (CHOP), were increased in the nontransplantation group (NTx) compared to the control group. …”
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    Activation of the EGFR-PI3K-CaM pathway by PRL-1-overexpressing placenta-derived mesenchymal stem cells ameliorates liver cirrhosis via ER stress-dependent calcium
  17. 144457
    “…These findings from an experimental model are translatable to the clinical peri-operative environment in which myocardial deformation may have the potential to guide blood pressure management, in particular at varying individual autoregulation thresholds.…”
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    Assessment of Myocardial Function During Blood Pressure Manipulations Using Feature Tracking Cardiovascular Magnetic Resonance
  18. 144458
    “…Gene ontology analysis revealed significant enrichment of dynamic modules in pathways including translation, protein metabolic/catabolic processes, protein complex assembly, and endocytosis. …”
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    Analysis of multiple gene co-expression networks to discover interactions favoring CFTR biogenesis and ΔF508-CFTR rescue
  19. 144459
    “…However, auxiliary research is needed to help translate an HCC risk prediction into an HCC-screening decision. …”
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    Performance of models to predict hepatocellular carcinoma risk among UK patients with cirrhosis and cured HCV infection
  20. 144460
    “…Cascade parents reported a short-term improvement in their confidence to use the skills they learnt, but this did not translate into actual use. After six months, Cascade parents felt their child survivor had lower psychological health than waitlisted parents. …”
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    Providing Psychological Support to Parents of Childhood Cancer Survivors: ‘Cascade’ Intervention Trial Results and Lessons for the Future
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