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144501por Garbern, Stephanie Chow, Nelson, Eric J, Nasrin, Sabiha, Keita, Adama Mamby, Brintz, Ben J, Gainey, Monique, Badji, Henry, Nasrin, Dilruba, Howard, Joel, Taniuchi, Mami, Platts-Mills, James A, Kotloff, Karen L, Haque, Rashidul, Levine, Adam C, Sow, Samba O, Alam, Nur Haque, Leung, Daniel T“…This investigation was also supported by the University of Utah Population Health Research (PHR) Foundation, with funding in part from the National Center for Advancing Translational Sciences of the National Institutes of Health under Award Number UL1TR002538. …”
Publicado 2022
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144502por Bartsch, Sarah M, O'Shea, Kelly J, Chin, Kevin L, Strych, Ulrich, Ferguson, Marie C, Bottazzi, Maria Elena, Wedlock, Patrick T, Cox, Sarah N, Siegmund, Sheryl S, Hotez, Peter J, Lee, Bruce Y“…FUNDING: The Agency for Healthcare Research and Quality, the National Institute of General Medical Sciences, the National Science Foundation, the National Center for Advancing Translational Sciences, and the City University of New York.…”
Publicado 2022
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144503por McNeil, Michael J., Ehrlich, Bella S., Wang, Huiqi, Vedaraju, Yuvanesh, Bustamante, Marisol, Dussel, Veronica, Friedrich, Paola, Garcia Quintero, Ximena, Gillipelli, Srinithya R., Gomez Garcia, Wendy, Graetz, Dylan E., Kaye, Erica C., Metzger, Monika L., Sabato Danon, Carla Vittoria, Devidas, Meenakshi, Baker, Justin N., Agulnik, Asya“…The survey was modified for use in Latin America, including translation into Spanish and adaptation for cultural context. …”
Publicado 2022
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144504por Dorhout, Berber G., de Groot, Lisette C.P.G.M., van Dongen, Ellen J.I., Doets, Esmée L., Haveman-Nies, Annemien“…An intervention that was translated across settings is ProMuscle: a diet and resistance exercise intervention for older adults. …”
Publicado 2022
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144505“…METHODS: Forward–backward procedure was used to translate the original questionnaire from English into Swiss French. …”
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144506por Marconato, Laura, Melacarne, Alessia, Aralla, Marina, Sabattini, Silvia, Tiraboschi, Luca, Ferrari, Valentina, Zeira, Offer, Balboni, Andrea, Faroni, Eugenio, Guerra, Dina, Pisoni, Luciano, Ghezzi, Erica, Pettinari, Letizia, Rescigno, Maria“…By using a bacterial-based strategy for vaccine development, we report an efficacious induction of an immune response, ultimately translating in improved outcome compared with historical controls receiving standard-of-care treatment. …”
Publicado 2022
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144507por Rogowski, Paul, Trapp, Christian, von Bestenbostel, Rieke, Eze, Chukwuka, Ganswindt, Ute, Li, Minglun, Unterrainer, Marcus, Zacherl, Mathias J., Ilhan, Harun, Beyer, Leonie, Kretschmer, Alexander, Bartenstein, Peter, Stief, Christian, Belka, Claus, Schmidt-Hegemann, Nina-Sophie“…CONCLUSIONS: Overall, the present analysis shows that the so far, unmatched sensitivity and specificity of PSMA-PET/CT translates in comparably high BRFS and DMFS after PSMA-PET/CT-based sENRT for patients with PCa LN recurrence. …”
Publicado 2021
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144508por Ao, Hui, Wang, Zhuo, Lu, Likang, Ma, Hongwei, Li, Haowen, Fu, Jingxin, Li, Manzhen, Han, Meihua, Guo, Yifei, Wang, Xiangtao“…Tumor-targeted drug delivery proves to be the best way to solve this problem; however, the complex synthesis, or surface modification process, together with the astonishing high cost make its clinical translation nearly impossible. METHODS: Referring to Ouyang’s work and over-threshold dosing theory in general, blank PEGylated liposomes (PEG-Lipo) were prepared and used as tumor delivery enhancers to determine whether they could significantly enhance the tumor accumulation and in vivo antitumor efficacy of co-injected liposomal ACGs (PEG-ACGs-Lipo), a naturally resourced chemotherapeutic. …”
Publicado 2022
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144509por Ajaka, Nahi, Bouché, Pierre-Alban, Dagher, Michel, Lopes, Ronny, Bauer, Thomas, Hardy, Alexandre“…PURPOSE: The aim of this study was to translate, adapt and validate in French the Ankle Ligament Reconstruction - Return to Sport after Injury (ALR-RSI), a 12-item English language scale assessing the psychological impact of returning to sports after ACL reconstruction. …”
Publicado 2022
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144510por Liu, Yiran E., Saul, Sirle, Rao, Aditya Manohar, Robinson, Makeda Lucretia, Agudelo Rojas, Olga Lucia, Sanz, Ana Maria, Verghese, Michelle, Solis, Daniel, Sibai, Mamdouh, Huang, Chun Hong, Sahoo, Malaya Kumar, Gelvez, Rosa Margarita, Bueno, Nathalia, Estupiñan Cardenas, Maria Isabel, Villar Centeno, Luis Angel, Rojas Garrido, Elsa Marina, Rosso, Fernando, Donato, Michele, Pinsky, Benjamin A., Einav, Shirit, Khatri, Purvesh“…The model has potential to be translated to a point-of-care prognostic assay to reduce dengue morbidity and mortality without overwhelming limited healthcare resources. …”
Publicado 2022
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144511por Schiavi, Margherita, Fugazzaro, Stefania, Bertolini, Anna, Denti, Monica, Mainini, Carlotta, Accogli, Monia Allisen, Bedogni, Ginevra, Ghizzoni, Daniele, Esseroukh, Otmen, Gualdi, Cecilia, Costi, Stefania“…An empirical phenomenological approach was used by the researchers, who independently analyzed the data and, through consensus, developed an interpretative model to answer the research question. Translation occurred after data was analyzed. RESULTS: During the first peak of the COVID-19 pandemic, 784 individuals with COVID-19 were discharged from the hospitals of the Local Health Authority of the Province of Reggio Emilia (Italy); 446 were excluded due to the presence of acute or chronic conditions causing disability other than COVID-19 (n. 339), inability to participate in the study procedures (n. 56), insufficient medical documentation to allow for screening (n. 21), discharge to residential facilities (n. 25), and pregnancy (n. 5). …”
Publicado 2022
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144512por Buregyeya, Esther, Atusingwize, Edwinah, Sekandi, Juliet N., Mugambe, Richard, Nuwematsiko, Rebecca, Atuyambe, Lynn“…Facilitators were; physical capability (availability of free TB services in the public health facilities), social opportunity (availability of translators). We identified education, incentivization, training, enablement, and restructuring of the service environment as relevant intervention functions with potential to address barriers to and enhance facilitators of TB case finding and retention among refugees in urban slums. …”
Publicado 2022
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144513por Chen, Jianguo, Huang, Tianyu, Liu, Ruiquan, Wang, Chenyu, Jiang, Haiyue, Sun, Hengyun“…Additionally, some hurdles, such as the low yield and unsatisfactory therapeutic effects of natural exosomes have emerged when considering the translation of exosomes-therapeutics to clinical practices or industrial production. …”
Publicado 2022
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144514por Jenkins, Catherine L, Imran, Sumayyah, Mahmood, Aamina, Bradbury, Katherine, Murray, Elizabeth, Stevenson, Fiona, Hamilton, Fiona L“…Digital health interventions are a double-edged sword: they have the potential to reduce health inequalities, for example, by making treatments available remotely to rural populations underserved by health care facilities or by helping to overcome language barriers via in-app translation services; however, if not designed and deployed with care, digital health interventions also have the potential to increase health inequalities and exacerbate the effects of the digital divide. …”
Publicado 2022
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144515por Wang, Zheng, Sun, Anqi, Yan, Aihui, Yao, Jian, Huang, Haibo, Gao, Ziming, Han, Tao, Gu, Jia, Li, Ni, Wu, Huizhe, Li, Kai“…Mechanistically, circMTCL1 directly recruited C1QBP protein by harboring the specific recognized sequence (+ 159 − + 210), thereby accelerating the translation of C1QBP expression by inhibiting its ubiquitin–proteasome-mediated degradation. …”
Publicado 2022
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144516por Glienke, Wolfgang, Dragon, Anna Christina, Zimmermann, Katharina, Martyniszyn-Eiben, Alexandra, Mertens, Mira, Abken, Hinrich, Rossig, Claudia, Altvater, Bianca, Aleksandrova, Krasimira, Arseniev, Lubomir, Kloth, Christina, Stamopoulou, Andriana, Moritz, Thomas, Lode, Holger N., Siebert, Nikolai, Blasczyk, Rainer, Goudeva, Lilia, Schambach, Axel, Köhl, Ulrike, Eiz-Vesper, Britta, Esser, Ruth“…Based on our previous development and validation of automated and closed processing for GMP-compliant manufacturing of CAR T cells, we here present the proof of feasibility for translation of this method to TRUCKs. We generated IL-18-secreting TRUCKs targeting the tumor antigen GD(2) using the CliniMACS Prodigy(®) system using a recently described “all-in-one” lentiviral vector combining constitutive anti-GD(2) CAR expression and inducible IL-18. …”
Publicado 2022
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144517por Chacon, Andrew, Kielly, Marissa, Rutherford, Harley, Franklin, Daniel R., Caracciolo, Anita, Buonanno, Luca, D’Adda, Ilenia, Rosenfeld, Anatoly, Guatelli, Susanna, Carminati, Marco, Fiorini, Carlo, Safavi-Naeini, Mitra“…A key requirement for NCEPT’s translation is the development of in vivo dosimetry techniques which can measure both the direct ion dose and the dose due to neutron capture. …”
Publicado 2022
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144518por Rosen, Rochelle K, Garbern, Stephanie C, Gainey, Monique, Lantini, Ryan, Nasrin, Sabiha, Nelson, Eric J, Elshabassi, Nour, Alam, Nur H, Sultana, Sufia, Hasnin, Tahmida, Qu, Kexin, Schmid, Christopher H, Levine, Adam C“…Each discussion was conducted in the local language—Bangla—and audio recorded for transcription and translation by the local research team. Transcripts and codes were entered into NVivo (version 12; QSR International), and applied thematic analysis was used to identify themes that explore the clinical utility of an mHealth app for assessing dehydration severity in patients with acute diarrhea. …”
Publicado 2022
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144519por Gans, Kim M., Tovar, Alison, Kang, Augustine, Ward, Dianne Stanton, Stowers, Kristen Cooksey, von Ash, Tayla, Dionne, Laura, Papandonatos, George Dennis, Mena, Noereem, Jiang, Qianxia, Risica, Patricia Markham“…Future research could include enhancing the Healthy Start intervention to strengthen the PA component, considering virtual peer support, and determining how to best translate and disseminate the intervention into FCCH nationally. …”
Publicado 2022
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144520por Koivisto, Antti Joonas, Jayjock, Michael, Hämeri, Kaarle J, Kulmala, Markku, Van Sprang, Patrick, Yu, Mingzhou, Boor, Brandon E, Hussein, Tareq, Koponen, Ismo K, Löndahl, Jakob, Morawska, Lidia, Little, John C, Arnold, Susan“…The models calculate a subjective exposure score, which is then translated to an exposure level (mg m(−3)) by using a calibration factor. …”
Publicado 2021
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