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144561por Hagley, Simon P., Kruppert, Anne, Leal, Rodolfo Oliveira, Pizarro del Valle, José Carlos, Iannucci, Claudia, Hennink, Imke, Boiron, Ludivine, Hoehne, Sabrina N.“…METHODS: A previously published online questionnaire from Switzerland was adapted and translated into 7 languages, corresponding to national languages in Austria, France, Germany, Ireland, Italy, Liechtenstein, Netherlands, Portugal, Spain, and the United Kingdom. …”
Publicado 2022
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144562por Wissemann, Ann Kathrin, Pit, Sabrina Winona, Serafin, Patrick, Gebhardt, Hansjürgen“…METHODS: International standardization practices, ethical frameworks, collaborative research, and use cases are used to demonstrate how technological solutions can be translated into practice and formed the basis for the development of a set of recommendations to create and maintain a sustainable aging workforce. …”
Publicado 2022
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144563por Karas, Marta, Muschelli, John, Leroux, Andrew, Urbanek, Jacek K, Wanigatunga, Amal A, Bai, Jiawei, Crainiceanu, Ciprian M, Schrack, Jennifer A“…OBJECTIVE: We aimed to compare objective measures of physical activity to increase the generalizability and translation of findings of studies that use accelerometry-based data. …”
Publicado 2022
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144564“…A face-to-face resilience enhancement training program for nurses that was effective in improving resilience levels was translated into a 4-week online training program, Resilience Enhancement Online Training for Nurses (REsOluTioN), to enable greater accessibility for nurses. …”
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144565por Jones, Laura B, Judkowicz, Carolina, Hudec, Kristen L, Munthali, Richard J, Prescivalli, Ana Paula, Wang, Angel Y, Munro, Lonna, Xie, Hui, Pendakur, Krishna, Rush, Brian, Gillett, James, Young, Marisa, Singh, Diana, Todorova, Antoaneta A, Auerbach, Randy P, Bruffaerts, Ronny, Gildea, Sarah M, McKechnie, Irene, Gadermann, Anne, Richardson, Chris G, Sampson, Nancy A, Kessler, Ronald C, Vigo, Daniel V“…METHODS: The online survey is based on the WMH-ICS survey instrument, modified to the Canadian context by the addition of questions pertaining to Canadian-based guidelines and the translation of the survey to Canadian French. The survey is administered through the Qualtrics survey platform and is sent to an independent stratified random sample of 350 students per site weekly, followed by two reminder emails. …”
Publicado 2022
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144566por Viola, Adrienne S, Levonyan-Radloff, Kristine, Masterson, Margaret, Manne, Sharon L, Hudson, Shawna V, Devine, Katie A“…The major barrier and facilitator themes identified included knowledge of cancer history and risks; relationships with health care providers; relationships with family members involved in care; emotions about health, follow-up care, and transfer of care; and lifestyle behaviors and life transitions. These themes were translated into 5 self-management modules: understanding treatment history and the survivorship care plan, managing health care logistics and insurance, communicating with health care providers and family members involved in care, dealing with emotions, and staying healthy in the context of life transitions. …”
Publicado 2022
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144567por Wang, Cheng, Hu, Zhoumi, Ding, Fan, Zhao, Haitao, Du, Fuqiang, Lv, Chun, Li, Lianghua, Huang, Gang, Liu, Jianjun“…Conclusion: (11)C-RJ1101 and (11)C-RJ1102 are interesting candidates for translation to the clinic, taking advantage of the shorter half-life and physical imaging properties of C-11.…”
Publicado 2022
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144568por dos Santos, José Carlos, Schäfer, Martin, Bauder-Wüst, Ulrike, Beijer, Barbro, Eder, Matthias, Leotta, Karin, Kleist, Christian, Meyer, Jan-Philip, Dilling, Thomas R., Lewis, Jason S., Kratochwil, Clemens, Kopka, Klaus, Haberkorn, Uwe, Mier, Walter“…The novel PSMA ligands, in particular CA028 and CA030, are promising agents for targeting PSMA-positive tumor lesions as shown in the preclinical evaluation and in a first patient, respectively. Thus, clinical translation of (68)Ga-CA028 and (68)Ga/(177)Lu-CA030 for diagnostics and endoradiotherapy of prostate cancer in larger cohorts of patients is warranted.…”
Publicado 2022
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144569por Yakupu, Aobuliaximu, Zhang, Jie, Dong, Wei, Song, Fei, Dong, Jiaoyun, Lu, Shuliang“…And from the relationship of EAPCs with SDI, UHC index, and GDP, indicate that prevention burns not only depend on health spending per capita but also depend on the education level per capita and healthcare system performance, but it does not mean higher health spending corresponds to higher UHC index, which needs high efficiency of translating health spending into individuals health gains. …”
Publicado 2022
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144570por Tari, Atefe R., Selbæk, Geir, Franklin, Barry A., Bergh, Sverre, Skjellegrind, Håvard, Sallis, Robert E., Bosnes, Ingunn, Stordal, Eystein, Ziaei, Maryam, Lydersen, Stian, Kobro-Flatmoen, Asgeir, Huuha, Aleksi M., Nauman, Javaid, Wisløff, Ulrik“…BACKGROUND: The Personal Activity Intelligence (PAI) translates heart rate during daily activity into a weekly score. …”
Publicado 2022
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144571por Trist, Benjamin G., Fifita, Jennifer A., Hogan, Alison, Grima, Natalie, Smith, Bradley, Troakes, Claire, Vance, Caroline, Shaw, Christopher, Al-Sarraj, Safa, Blair, Ian P., Double, Kay L.“…These data are essential to guide therapeutic development and enhance the translation of relevant therapies into the clinic. Our group recently profiled SOD1 proteinopathy in post-mortem spinal cord tissues from familial and sporadic ALS cases, demonstrating an abundance of structurally-disordered (dis)SOD1 conformers which become mislocalized within these vulnerable neurons compared with those of aged controls. …”
Publicado 2022
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144572por Yao, Chongjie, Ren, Jun, Huang, Ruixin, Tang, Cheng, Cheng, Yanbin, Lv, Zhizhen, Kong, Lingjun, Fang, Sitong, Tao, Jiming, Fu, Yangyang, Zhu, Qingguang, Fang, Min“…CONCLUSIONS: In rats, CCD-induced neuropathic pain leads to variation in miRNA expression in DRG, and MT can intervene the transcription and translation of inflammation-related genes through miRNAs to improve neuroinflammation and alleviate neuropathic pain. …”
Publicado 2022
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144573por Mondal, Amalesh, Paul, Debarati, Dastidar, Shubhra Ghosh, Saha, Tanima, Goswami, Achintya Mohan“…These 10 nsSNPs are also predicted to affect the post-translational modifications of Wnt1. Further, structure based stability analyses of these 10 highly deleterious nsSNPs revealed 8 variants as highly destabilizing. …”
Publicado 2022
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144574por Amheka, Adrianus, Nguyen, Hoa Thi, Yu, Krista Danielle, Noach, Robert Mesakh, Andiappan, Viknesh, Dacanay, Vincent Joseph, Aviso, Kathleen“…BACKGROUND: Economic growth is dependent on economic activity, which often translates to higher levels of carbon emissions. With the emergence of technologies that promote sustainable production, governments are working towards achieving their target economic growth while minimizing environmental emissions to meet their commitments to the international community. …”
Publicado 2022
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144575por Brooks, Helen, Devereux-Fitzgerald, Angela, Richmond, Laura, Caton, Neil, Newton, Alice, Downs, James, Lovell, Karina, Bee, Penny, Cherry, Mary Gemma, Young, Bridget, Vassilev, Ivaylo, Rotheram, Clare, Rogers, Anne“…Although these elements have been shown to improve service user and service-level outcomes, their translation into practice has been inconsistent and social isolation amongst service users persists. …”
Publicado 2022
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144576por Fokam, Joseph, Alteri, Claudia, Colagrossi, Luna, Genevieve, Anne-Marie, Takou, Désiré, Ndjolo, Alexis, Colizzi, Vittorio, Ndembi, Nicaise, Perno, Carlo-Federico“…For this purpose, we will create a platform enabling researchers/clinicians to better integrate and translate evidence into the COVID-19 clinical-practice; (b) to enhance capacities in Cameroon for screening/detecting individuals with high-risks of COVID-19, by setting-up effective core-facilities on-site; (c) to validate point-of-care SARS-CoV-2 molecular assays allowing same-day result delivery, thus permitting timely diagnosis, treatment, and retention in care of COVID-19 patients; (d) to implement SARS-CoV-2 diagnosis with innovative/highly sensitive ddPCR-based assays and viral genetic characterization; (e) to validate serological assays to identify COVID-19-exposed persons and follow-up of convalescents. …”
Publicado 2022
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144577por Meiring, S., Busch, C. B. E., van Baar, A. C. G., Hemke, R., Holleman, F., Nieuwdorp, M., Bergman, J. J. G. H. M.“…However, it is not yet clear whether these improvements will translate into a true reduction in cardiovascular events. …”
Publicado 2022
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144578por Fuchs, Elisabeth, Rudnik-Jansen, Imke, Dinesen, Anders, Selnihhin, Denis, Mandrup, Ole Aalund, Thiam, Kader, Kjems, Jørgen, Pedersen, Finn Skou, Howard, Kenneth A.“…FcRn-mediated in vitro recycling was translated to a five times greater plasma half-life of WT-ACE2 (t(½) β = 13.5 h) than soluble ACE2 (t(½) β = 2.8 h) in humanised FcRn/albumin double transgenic mice. …”
Publicado 2022
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144579por Fahmi, Naima Ahmed, Ahmed, Khandakar Tanvir, Chang, Jae-Woong, Nassereddeen, Heba, Fan, Deliang, Yong, Jeongsik, Zhang, Wei“…Thus, 3′-UTR APA is known to modulate translation and provides a mean to regulate gene expression at the post-transcriptional level. …”
Publicado 2022
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144580“…The gene ontology enrichment analysis showed that those down- and upregulated genes were involved in dephosphorylation and regulation of translation, respectively. The final immune-related core ceRNA network included one lncRNA (LINC00221), two miRNAs (miR-17-5p and miR-20b-5p), and one mRNA (CREB1). …”
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