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  1. 144581
    “…This statement was developed to facilitate clinical translation of GWS as a prenatal diagnostic test and the development of best practices in Canada, but the applicability of this document is broader and aims to help professionals in other healthcare systems. …”
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    Clinical application of fetal genome-wide sequencing during pregnancy: position statement of the Canadian College of Medical Geneticists
  2. 144582
    “…Follow-up studies indicated that miR-585-5p targets the downstream molecules CREB1 and MAPK1 to regulate the transcriptional and post-translational regulation of MITF, respectively, thus controlling its expression and cancer-promoting activity. …”
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    MiR-585-5p impedes gastric cancer proliferation and metastasis by orchestrating the interactions among CREB1, MAPK1 and MITF
  3. 144583
    por Gnat, Sebastian
    Publicado 2022
    “…The main city of the agglomeration showed a tendency to pull in the economic potential from the region, which translated into a faster increase in real estate prices in the capital of the region in comparison with the surrounding cities. …”
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    Convergence of residential property prices in the Szczecin agglomeration in the context of the COVID-19 pandemic
  4. 144584
    “…Testing these indices across larger samples is necessary to generalize these findings and translate performance to adults.…”
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    A performance review of novel adiposity indices for assessing insulin resistance in a pediatric Latino population
  5. 144585
    “…All interviews were audio-recorded, transcribed verbatim in Chinese, and translated into English for data analysis. We conducted a thematic analysis using a codebook, which was guided by a team-based consensus approach to identify 5 main themes. …”
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    Factors Related to Smoking and Perceptions of a Behavioral Counseling and Messenger Service–Delivered Smoking Cessation Intervention for People With HIV in China: Qualitative Study
  6. 144586
    “…The biological activity of antimicrobial peptides and proteins is closely related to their structural aspects and is sensitive to certain post-translational modifications such as glycosylation, lipidation and PEGylation. …”
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    PEGylation of the antimicrobial peptide LyeTx I-b maintains structure-related biological properties and improves selectivity
  7. 144587
    “…Even though most CNAs are comfortable with training in English only, we will translate curricula into Spanish to support our bilingual Spanish-canaking CNA population. …”
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    Using a learning needs assessment to develop infection prevention training for certified nursing assistants
  8. 144588
    “…Trial registration The protocol for this project was previously published, and the project was preregistered on Open Science Framework (Clyne and Sharp, Evidence synthesis and translation of findings for national clinical guideline development: addressing the needs and preferences of guideline development groups, 2021; Sharp and Clyne, Evidence synthesis summary formats for decision-makers and Clinical Guideline Development Groups: A mixed-methods systematic review protocol, 2021). …”
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    The effectiveness and acceptability of evidence synthesis summary formats for clinical guideline development groups: a mixed-methods systematic review
  9. 144589
    “…CONCLUSIONS: Our team and knowledge translation plan is engaging patient partners, researchers, knowledge users, and policy group representatives. …”
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    KIdney aNd blooD prESsure ouTcomes in Childhood Cancer Survivors: Description of Clinical Research Protocol of the KINDEST-CCS Study
  10. 144590
    “…RNA sequencing of blood at diagnosis identified that patients relapsing after treatment are characterized by significant enrichment of gene signatures related to cell cycle, MYC target genes, metabolism and translation regulation. Conversely, patients achieving CR with BM uMRD displayed significant enrichment in genes related to communication between CLL cells and the microenvironment, immune system activation and upregulation of polycomb PRC2 complex target genes. …”
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    miRNA profile at diagnosis predicts treatment outcome in patients with B-chronic lymphocytic leukemia: A FILO study
  11. 144591
    “…(threshold)=0.84), both automated quantification methods translated to the semi-quantitative CCS in a non-linear fashion, with an increasing slope towards higher CCS (r(2)(deep-learning) (vs.) …”
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    Assessment of COVID-19 lung involvement on computed tomography by deep-learning-, threshold-, and human reader-based approaches—an international, multi-center comparative study
  12. 144592
    “…Future research will focus on analyzing concrete data in a target unit to assess translation of the intervention to improved quality of inpatient glycemic control. …”
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    PSUN224 Resident Education for Improved Quality and Confidence in Inpatient Hyperglycemia Management
  13. 144593
    “…The lncRNA transcripts are longer than 200 nucleotides and are often capped, spliced and polyadenylated, but they are not translated into proteins. Nuclear lncRNAs modify chromatin structure and transcription in trans or cis by interacting with the DNA, forming R-loops, and recruiting regulatory proteins. …”
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    RF13 | PMON142 Long Non-coding RNAs in Pituitary Differentiation and Endocrine Function
  14. 144594
    “…OBJECTIVE: To address the need to qualify RWD, we aimed to build a web application as a tool to translate characterization of some quality parameters of RWD into a metric and propose a standard framework for evaluating the quality of the RWD. …”
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    RWD-Cockpit: Application for Quality Assessment of Real-world Data
  15. 144595
    “…Expression levels were reported at the transcriptional level by quantitative real-time polymerase chain reaction, and at the translational level by Western blotting and immunofluorescence. …”
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    Expression of the methylcytosine dioxygenase ten-eleven translocation-2 and connexin 43 in inflammatory bowel disease and colorectal cancer
  16. 144596
    “…Together, our data support the clinical translation of CAR-T20 for R/R B-cell NHL patients. …”
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    Pre-clinical efficacy of CD20-targeted chimeric antigen receptor T cells for non-Hodgkin's lymphoma
  17. 144597
    “…Although unmeasured confounding cannot be excluded as an explanation for our findings, virological benefits of first-line INSTIs-based ART might not translate to differences in mortality. FUNDING: US National Institute on Alcohol Abuse and Alcoholism and UK Medical Research Council.…”
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    Associations of modern initial antiretroviral drug regimens with all-cause mortality in adults with HIV in Europe and North America: a cohort study
  18. 144598
    “…CONCLUSION: Given the promising preclinical results of these PD-L1-inhibiting miRs in inhibiting NSCLC development, their ectopic expression might improve NSCLC patients’ prognosis; however, further studies are needed to translate this approach into clinical practice.…”
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    A scoping review on the significance of programmed death-ligand 1-inhibiting microRNAs in non-small cell lung treatment: A single-cell RNA sequencing-based study
  19. 144599
    “…E2F-related genes played a role in development and differentiation, and were prevalent in the endoplasmic reticulum lumen, Golgi lumen, and lipoprotein particle, catalyzing translation activities and lipid metabolism. Each gene was found to be related to each other to some degree. …”
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    A bioinformatics analysis for diagnostic roles of the E2F family in esophageal cancer
  20. 144600
    “…The results of this review may be useful to public health care professionals, managers, policymakers, and the general population because these findings will help understand the validated, translated, and adapted versions of MBI and domains, number of items, Likert scales, and cutoff points or the latent profile analysis most used in the literature. …”
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    Use of the Maslach Burnout Inventory Among Public Health Care Professionals: Protocol for a Scoping Review
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