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  1. 145741
    “…All in-depth interviews and group discussions were audio-recorded, transcribed verbatim and translated to English. Data were analysed using framework analysis. …”
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    A qualitative study to explore daily versus on-demand oral pre-exposure prophylaxis (PrEP) in young people from South Africa, Uganda and Zimbabwe
  2. 145742
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    Online Artículo Texto
    Real-world analysis of first-line afatinib in patients with EGFR-mutant non-small cell lung cancer and brain metastasis: survival and prognostic factors
  3. 145743
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    Efficacy, cardiotoxicity and factors affecting pathologic complete response of neoadjuvant chemotherapy with anthracycline-containing verses anthracycline-free regimens plus dual HER2 blockade for HER2-positive early-stage breast cancer: a retrospective study
  4. 145744
    “…Lp(a)-reducing therapies may reduce the burden from arteriosclerotic events throughout the arterial system. TRANSLATIONAL PERSPECTIVE: In 2354 participants from the Rotterdam study, we assessed the link between Lp(a) concentrations and arterial calcifications, as proxy for arteriosclerosis, in major arteries. …”
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    Lipoprotein(a) is associated with a larger systemic burden of arterial calcification
  5. 145745
    por Hoang, Nhung Huyen, Liang, Zilu
    Publicado 2023
    “…Future research should address the challenges related to collecting high-quality data, extracting hidden knowledge from data while accommodating within-individual and between-individual variations, and translating the discovered knowledge into actionable insights.…”
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    Online Artículo Texto
    Knowledge Discovery in Ubiquitous and Personal Sleep Tracking: Scoping Review
  6. 145746
    “…When tuning our brain imaging analysis to the spatial precision of the top-down connections from higher- to lower-level visual areas, do higher areas project their coarse spatial tuning or is this processing translated to the high-precision coding of the lower-level target region they are projecting to? …”
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    The Spatial Precision of Contextual Feedback Signals in Human V1
  7. 145747
    “…Members with carve-in benefits had lower medical costs after adjustment (4%, P < 0.001), translating into an average $148 lower medical cost PMPY ($3,749 carve-out vs. $3,601 carve-in annualized). …”
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    Medical Costs and Health Care Utilization Among Self-Insured Members with Carve-In Versus Carve-Out Pharmacy Benefits
  8. 145748
    “…Rationale: As a key endogenous negative regulator of ferroptosis, glutathione peroxidase 4 (GPX4) can regulate its antioxidant function through multiple post-translational modification pathways. However, the effects of the phosphorylation/dephosphorylation status of GPX4 on the regulation of inducible ferroptosis in hepatocellular carcinoma (HCC) remain unclear. …”
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    Protein phosphatase 2A-B55β mediated mitochondrial p-GPX4 dephosphorylation promoted sorafenib-induced ferroptosis in hepatocellular carcinoma via regulating p53 retrograde signaling
  9. 145749
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    First-line osimertinib for patients with EGFR-mutated advanced non-small cell lung cancer: efficacy and safety during the COVID-19 pandemic
  10. 145750
    “…The identified predictors and their impact on survival offered additional value for translational application in clinical practice.…”
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    Predicting Overall Survival for Patients with Malignant Mesothelioma Following Radiotherapy via Interpretable Machine Learning
  11. 145751
    “…This model has important translational implications, which can be used to identify a subset of patients who are not likely to benefit from immunotherapy. …”
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    A Radiomics-Clinical Model Predicts Overall Survival of Non-Small Cell Lung Cancer Patients Treated with Immunotherapy: A Multicenter Study
  12. 145752
    “…Despite higher treatment persistence among patients adding a third OAD, this persistence did not translate into better glycemic control and may not necessarily be a long-term cost-saving solution. …”
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    Outcomes and Treatment Patterns of Adding a Third Agent to 2 OADs in Patients with Type 2 Diabetes
  13. 145753
    “…Similarly, our findings confirm the appropriateness of this translational model in the evaluation of brain neuronal circuit EMF and that preoperative and post-trauma differences can be appropriately assessed with this technology.…”
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    A Swine Model of Traumatic Brain Injury: Effects of Neuronally Generated Electromagnetic Fields and Electromagnetic Field Stimulation on Traumatic Brain Injury-Related Changes
  14. 145754
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    Human aortic smooth muscle cell regulation by METTL3 via upregulation of m6A NOTCH1 modification and inhibition of NOTCH1
  15. 145755
    “…CONCLUSION: These results underscore the possibility of chemotherapy-induced leukoencephalopathy months post-treatment, as well as the added value of serum-NfL as a prognostic marker for peripheral/central neurotoxicity. TRANSLATIONAL RELEVANCE: Previous case studies have provided evidence of chemotherapy-induced leukoencephalopathy in patients with breast cancer. …”
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    Changes in leukoencephalopathy and serum neurofilament after (neo)adjuvant chemotherapy for breast cancer
  16. 145756
    “…The simulation study results elucidated key areas for improvement that translated into actionable next steps in app development.…”
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    Outcomes of End-User Testing of a Care Coordination Mobile App With Families of Children With Special Health Care Needs: Simulation Study
  17. 145757
    “…Swine models have begun to be evaluated as translational models in this effect. Methods EMF measurements of a Yucatan miniswine were recorded using proprietary non-contact, non-invasive induction sensors with a dual layer Mu-metal and interlaced copper mesh helmet. …”
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    A Swine Model of Neural Circuit Electromagnetic Fields: Effects of Immediate Electromagnetic Field Stimulation on Cortical Injury
  18. 145758
    “…We projected that for every 100 children starting either ATT or TPT at baseline, the intervention package translated to between 1 (95% UI, −1 to 3) and 38 (95% UI, 24 to 58) deaths averted, with a median incremental cost-effectiveness ratio (ICER) of US$634 per disability-adjusted life year (DALY) averted. …”
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    Cost-effectiveness analysis of interventions to improve diagnosis and preventive therapy for paediatric tuberculosis in 9 sub-Saharan African countries: A modelling study
  19. 145759
    “…SIMPLE SUMMARY: This prospective translational study evaluated whether the presence of circulating tumor cells (CTCs) in the peripheral blood (PB) correlates with efficacy of cabazitaxel in patients with metastatic castration-resistant prostate cancer (mCRPC). …”
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    Prognostic Role of Circulating Tumor Cells in Patients with Metastatic Castration-Resistant Prostate Cancer Receiving Cabazitaxel: A Prospective Biomarker Study
  20. 145760
    “…RT-qPCR studies in T-47D cells revealed a transcriptional expression of ESR1 and BRCA-1 mRNA levels that correlate with the translational data from western blot analyses. Confocal microscopy, cell viability, and RT-qPCR analyses are in progress as well as evaluation on the effects of DP with hormones and antihormones on MCF-7 cells. …”
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    SAT428 The Effects Of Diphenyl Phthalate (DP) On Estrogen Receptor Alpha (ERα;) And Tumor Suppressor Gene (BRCA-1) In Breast Cancer Cells
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