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  1. 145761
    “…ADPRylation is a post-translational modification, which is catalyzed by the PARP family of ADP-ribosyl transferases and results in the covalent attachment of ADP-ribose on protein substrates. …”
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    OR16-02 Histone ADP-Ribosylation Site Mutations As Oncogenic Drivers In Breast And Ovarian Cancers
  2. 145762
    “…Signal-regulated post-translational modifications in the TAMs help modulate the transcriptional programs that mediate biological outcomes. …”
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    FRI011 Exploring The Contribution Of PARP1-mediated Site-specific ADP-Ribosylation Of C/EBPb In Macrophages To Diet-induced Obesity
  3. 145763
    “…The degree to which these methods translate to TAUS is unknown. Establishing standardized methods to analyze ovarian features via TAUS are needed to clarify the utility of ovarian morphology in the clinical evaluation of PCOS in adolescence. …”
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    SAT352 Reliability Of Two- And Three-dimensional Ultrasonographic Assessments Of Ovarian Morphology In Adolescents
  4. 145764
    “…At 120 minutes post-bolus, tissues were collected for isotopiccompound measurement, mitochondrial function assays, and insulin signalingpathway assessment. This translational swine model will help uncover themechanistic effects of testosterone therapy on insulin sensitivity and whole-bodymetabolism in female to male transitioning patients. …”
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    SAT415 Development Of A Novel, Preclinical Swine Model Of Transgender Men To Assess Testosterone Impact On Insulin Sensitivity And Whole-Body Metabolism
  5. 145765
    “…A phase 2b clinical study of bimagrumab +/- semaglutide is ongoing to learn if these favorable results will translate to humans (NCT05616013). Presentation: Friday, June 16, 2023…”
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    OR10-03 Murine Bimagrumab Co-administration With Incretin Agonists Results In Additive Efficacy And Superior Quality Weight Loss In The Mouse Diet-induced Obesity Model
  6. 145766
    “…These novel findings of sex-specific effects of gestational exposure to T excess on lipid metabolism of newborn lamb, a precocial model of translational relevance, may have sex-specific functional outcomes in cardiometabolic systems. …”
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    FRI103 Developmental Programming: Sex-specific Differences In Lipid Metabolism Of Newborn Lambs Exposed To Prenatal Testosterone Excess
  7. 145767
    “…Further studies are now needed to confirm and translate these findings, and to identify the links between SIRT1, and the pathognomonic FOXL2(C134W) mutation of GCT. …”
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    OR05-06 Histone Deacetylase Inhibitor, Panobinostat, In Combination With A Smac-mimetic For The Treatment Of Ovarian Granulosa Cell Tumours
  8. 145768
    “…This exclusion has translated to current clinical practice and therefore little is known about the safety and efficacy of ICI in this population. …”
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    THU299 Safety Of Immune Checkpoint Inhibitor Cancer Therapy In Patients With Pre-existing Type 1 Diabetes Mellitus: A Multi-Center Cohort Study
  9. 145769
    “…Notably, re‐expression of Cav3 in Cav3KO myoblasts normalized lysosomal cholesterol content, which coincided with a recovery in protein translation and an associated increase in mTORC1‐directed phosphorylation of downstream targets. …”
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    Caveolin‐3 loss linked with the P104L LGMD‐1C mutation modulates skeletal muscle mTORC1 signalling and cholesterol homeostasis
  10. 145770
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    Thyroid transcription factor-1 (TTF-1) expression and the efficacy of combination therapy with immune checkpoint inhibitors and cytotoxic chemotherapy in non-squamous non-small cell lung cancer
  11. 145771
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    The differential prognostic implications of PD-L1 expression in the outcomes of Filipinos with EGFR-mutant NSCLC treated with tyrosine kinase inhibitors
  12. 145772
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    Deep phenotyping of the lipidomic response in COVID‐19 and non‐COVID‐19 sepsis
  13. 145773
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    Risk of second cancer in esophageal squamous cell carcinoma and adenocarcinoma survivors: a population-based analysis in SEER dataset
  14. 145774
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    (68)Ga-PSMA-PET/CT in addition to mpMRI in men undergoing biopsy during active surveillance for low- to intermediate-risk prostate cancer: study protocol for a prospective cross-sectional study
  15. 145775
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    The clinicopathological characteristics and survival outcomes of primary expansile vs. infiltrative mucinous ovarian adenocarcinoma: a retrospective study sharing the experience of a tertiary centre
  16. 145776
    “…Here we show that split-dose, multi-site administration and intradermal delivery via the Tropis biojector increase the delivery of pBI-11 DNA vaccine, enhance HPV antigen-specific CD8+ T-cell responses, and improve anti-tumor therapeutic effects, suggesting its translational potential to treat HPV16/18 infection and disease.…”
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    Immune responses, therapeutic anti-tumor effects, and tolerability upon therapeutic HPV16/18 E6/E7 DNA vaccination via needle-free biojector
  17. 145777
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    Exploration of a novel prognostic model based on nomogram in non-small cell lung cancer patients with distant organ metastasis: implications for immunotherapy
  18. 145778
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    H. pylori‐induced NF‐κB‐PIEZO1‐YAP1‐CTGF axis drives gastric cancer progression and cancer‐associated fibroblast‐mediated tumour microenvironment remodelling
  19. 145779
    “…Decreased concern recovered in S4 but did not translate to increased vaccine uptake (Table 1). Caregivers were less scared of their child getting COVID-19 and more scared of the vaccine in S4. …”
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    1734. Influenza, SARS-CoV-2, and routine childhood vaccines – trends in vaccine hesitancy in hospitalized children before and during the COVID-19 pandemic
  20. 145780
    “…BACKGROUND: Telehealth (TH) offers valuable opportunities to improve healthcare delivery that may translate to better health outcomes. Utilization of TH by pediatric subspecialty programs has been successful in inpatient settings. …”
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    2323. Pediatric Infectious Diseases Outpatient Telehealth Services During the COVID-19 Pandemic: Single Center Experience
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