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145801por Houck, Jared, Kopietz, Courtni M., Shah, Bhavin C., Goede, Matthew R., McBride, Corrigan L., Oleynikov, Dmitry“…Participating surgeons significantly increased the number of course-specific procedures that they performed but also increased the number of other laparoscopic surgeries, suggesting that a certain proficiency in laparoscopic skills is translated to multiple surgical procedures. Laparoscopy experience of ≥50 cases during residency is a strong predictor of an increase in the number of advanced laparoscopic cases after attending courses.…”
Publicado 2013
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145802“…We also found that some well established procedures used in trials of e-SBI in the primary care setting did not translate to the hospital outpatient setting (1) we experienced delays because the e-SBI program had to be developed and maintained by the health service’s information technology staff for security reasons, (2) recruiting patients as they left the reception desk was impractical because patients tended to arrive at the beginning of the clinics with few arrivals thereafter, and (3) use of a laptop in a fixed location resulted in some patients rushing through the e-SBI so they could return to their seat in the area they had been advised to wait in. …”
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145803por Requejo, Jennifer, Merialdi, Mario, Althabe, Fernando, Keller, Matthais, Katz, Joanne, Menon, Ramkumar“…As new evidence is generated, resources need to be allocated to its translation into new and better screening and diagnostic tools, and other interventions aimed at saving maternal and newborn lives that can be brought to scale in all countries. …”
Publicado 2013
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145804por Svenson, Gavin J.“…Combined male and female genus and species level dichotomous keys are provided with a Spanish translation. A complete table of all examined specimens lists label data, museum codes, repositories, and other specimen specific information. …”
Publicado 2014
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145805“…The increased risk of infection may be because of either cancer itself or treatment-induced immunosuppression.1 Influenza immunization has been shown to decrease the risk of influenza infection in patients with intact immunity.2 In cancer patients, active immunization has been shown to confer protective immunity against several infections at similar rates to healthy individuals, which has translated into decreased duration and severity of infection and potentially improved morbidity and mortality.3 OBJECTIVES: 1. …”
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145806“…By approaching the spine laterally, it is possible to preserve the stabilizing ligaments, which are a natural restraint to excessive rotations and translations, and thereby help to minimize facet stresses. …”
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145807por Hoss, Andrew G, Labadorf, Adam, Latourelle, Jeanne C, Kartha, Vinay K, Hadzi, Tiffany C, Gusella, James F, MacDonald, Marcy E, Chen, Jiang-Fan, Akbarian, Schahram, Weng, Zhiping, Vonsattel, Jean Paul, Myers, Richard H“…BACKGROUND: MicroRNAs (miRNAs) are small non-coding RNAs that recognize sites of complementarity of target messenger RNAs, resulting in transcriptional regulation and translational repression of target genes. In Huntington’s disease (HD), a neurodegenerative disease caused by a trinucleotide repeat expansion, miRNA dyregulation has been reported, which may impact gene expression and modify the progression and severity of HD. …”
Publicado 2015
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145808por Carraro, Ugo, Boncompagni, Simona, Gobbo, Valerio, Rossini, Katia, Zampieri, Sandra, Mosole, Simone, Ravara, Barbara, Nori, Alessandra, Stramare, Roberto, Ambrosio, Francesco, Piccione, Francesco, Masiero, Stefano, Vindigni, Vincenzo, Gargiulo, Paolo, Protasi, Feliciano, Kern, Helmut, Pond, Amber, Marcante, Andrea“…Some of the mandatory procedures, are ready to be translated from animal experiments to clinical studies to meet the needs of persons with long-term irreversible muscle denervation. …”
Publicado 2015
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145809“…AUTHORS' CONCLUSIONS: Trials did show a small effect on average haemoglobin levels but this did not appear to translate into an effect on mortality and hospital admissions. …”
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145810por Krempf, Michel, Simpson, Ross J, Ramey, Dena Rosen, Brudi, Philippe, Giezek, Hilde, Tomassini, Joanne E, Lee, Raymond, Farnier, Michel“…CONCLUSIONS: This study provides insight into physicians’ perspectives on clinical management of hypercholesterolemia and highlights a gap in knowledge translation from guidelines to clinical practice. The need for lower LDL-C and cardiovascular risk were key drivers in clinical decision-making, but physicians’ treatment choices were more conservative than guideline recommendations, potentially resulting in poorer LDL-C reduction. …”
Publicado 2015
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145811por Konstantakou, Eumorphia G., Voutsinas, Gerassimos E., Velentzas, Athanassios D., Basogianni, Aggeliki-Stefania, Paronis, Efthimios, Balafas, Evangelos, Kostomitsopoulos, Nikolaos, Syrigos, Konstantinos N., Anastasiadou, Ema, Stravopodis, Dimitrios J.“…This bioenergetic crisis is translated to severe dysregulation of Akt/FoxO/GSK-3, mTOR/S6, AMPK and MAPK (p44/42, p38 and SAPK/JNK) signaling pathways in 3-BrPA-treated T24 cells. …”
Publicado 2015
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145812“…In addition, the ability to fully automate density estimation with digital mammography, particularly through the use of publically available breast density estimation software, could accelerate the translation of density reporting in routine breast cancer screening and surveillance protocols and facilitate broader research into the use of breast density as a risk factor for breast cancer. …”
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145813por Zhang, Yuji“…The enriched biological processes include translation elongation, nucleosome assembly, and retina development. …”
Publicado 2015
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145814por Li, Cheng, Lin, Ying, Zheng, Xueyun, Pang, Nuo, Liao, Xihao, Liu, Xiaoxiao, Huang, Yuanyuan, Liang, Shuli“…DISCUSSION: The production of a secreted protein will reach its limit at a specific gene copy number where further increases in transcription and translation due to the higher abundance of gene copies will not enhance the secretion process any further. …”
Publicado 2015
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145815“…BACKGROUND: Ribosomally synthesized and post-translationally modified peptides (RiPPs) are a burgeoning class of natural products with diverse activity that share a similar origin and common features in their biosynthetic pathways. …”
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145816por Kirigia, Joses Muthuri, Ota, Martin Okechukwu, Motari, Marion, Bataringaya, Juliet Evelyn, Mouhouelo, Pascal“…Of the countries responding to various questions 49 % (23/47) had a national health research policy; 47 % (22/47) had a health strategic plan; 40 % (19/47) had legislation governing research; 53 % (25/47) had a national health research priority agenda; 51 % (24/47) reported having a functional NHRS and a national health research management forum; 91 % (43/47) had an ethical review committee; 49 % (23/47) had hospitals with ethical review committees to review clinical research proposals; 51 % (24/47) had a scientific review committee; 62 % (29/47) had health institutions with scientific review committees; 83 % (39/47) had a national health research focal point; 51 % (24/47) had a health research programme; 55 % (26/47) had a national health or medical research institute or council; 93 % (41/44) had at least one university faculty of health sciences that conducted health research; and 33 % (15/46) had a knowledge translation platform. Forty-seven percent of countries reported having a budget line for research for health in the ministry of health budget. …”
Publicado 2015
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145817por Paterna, Salvatore, Di Gaudio, Francesca, La Rocca, Vincenzo, Balistreri, Fabio, Greco, Massimiliano, Torres, Daniele, Lupo, Umberto, Rizzo, Giuseppina, di Pasquale, Pietro, Indelicato, Sergio, Cuttitta, Francesco, Butler, Javed, Parrinello, Gaspare“…These findings were translated in an improvement in the furosemide dose–response curves in these patients. …”
Publicado 2015
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145818por Gourni, Eleni, Canovas, Coline, Goncalves, Victor, Denat, Franck, Meyer, Philipp T., Maecke, Helmut R.“…CONCLUSIONS: (68)Ga-CC34 is comparable to (68)Ga-HBED-CC-PSMA in terms of tumor uptake and tumor to normal tissue ratios. (64)Cu-CC34 could enable high contrast imaging of PSMA positive tissues characterized by elevated expression of PSMA or when delayed imaging is required. (64)Cu-CC34 is currently being prepared for clinical translation.…”
Publicado 2015
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145819por Traa, Marjan Johanna, Roukema, Jan Anne, De Vries, Jolanda, Rutten, Harm Jozef Theodorus, Langenhoff, Barbara, Jansen, Walther, Den Oudsten, Brenda LeontineEnlace del recurso
Publicado 2015
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145820