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145841por Bournet, Barbara, Muscari, Fabrice, Buscail, Camille, Assenat, Eric, Barthet, Marc, Hammel, Pascal, Selves, Janick, Guimbaud, Rosine, Cordelier, Pierre, Buscail, LouisEnlace del recurso
Publicado 2016
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145842
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145843“…Such advantages may translate to improved outcomes after irradiation in terms of disease control in radio-resistant and previously treated, recurrent malignancies. …”
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145844por Archambault, Patrick Michel, Beaupré, Pierre, Bégin, Laura, Dupuis, Audrey, Côté, Mario, Légaré, France“…Future studies need to explore if this increased intention will translate into sustained actual use and improve patient care. …”
Publicado 2016
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145845por Tang, Donge, Chen, Yuyu, He, Huiyan, Huang, Jianrong, Chen, Wenbiao, Peng, Wujian, Lu, Qianjin, Dai, Yong“…Through gene ontology (GO) analysis of differentially expressed mRNAs and proteins, biological processes that drive proliferation were identified, such as mRNA processing and translation. Western blot and Q-PCR confirmed AK4 protein and mRNA up-regulation. …”
Publicado 2016
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145846por Deslyper, Gwendoline, Colgan, Thomas J., Cooper, Andrew J. R., Holland, Celia V., Carolan, James C.“…A marked decrease in proteins associated with translation was also observed in both C57BL/6J and CBA/Ca mice under infection, indicative of either a general response to Ascaris or a modulatory effect by the nematode itself. …”
Publicado 2016
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145847por Katirayi, Leila, Chouraya, Caspian, Kudiabor, Kwashie, Mahdi, Mohammed Ali, Kieffer, Mary Pat, Moland, Karen Marie, Tylleskar, Thorkild“…FGDs were audio-recorded and simultaneously transcribed and translated into English. Analysis was conducted using thematic analysis. …”
Publicado 2016
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145848por Wang, Xin, Hao, Limin, Saur, Taixiang, Joyal, Katelyn, Zhao, Ying, Zhai, Desheng, Li, Jie, Pribadi, Mochtar, Coppola, Giovanni, Cohen, Bruce M., Buttner, Edgar A.“…Knock down/out of those two genes in EAB135 animals by feeding RNAi/introducing a known acp-4 null allele phenocopied the suppression of the C9ORF72 variant related movement defect in the mutant strains. Translational conformation in a mammalian system is required, but our worm data suggest that altering acp-4/ACP2 encoding lysosomal acid phosphatase may provide a potential therapeutic method of reducing acp-4/ACP2 levels, as opposed or complementary to directly reducing C9ORF72, to relieve C9ORF72-ALS phenotypes. …”
Publicado 2016
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145849“…In conclusion, the same degree of sensitivity from the 2D system did not translate to a 3D culture system, resulting in higher IC50 values than the 2D system. …”
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145850por Balmforth, Craig, van Bragt, Job J.M.H., Ruijs, Titia, Cameron, James R., Kimmitt, Robert, Moorhouse, Rebecca, Czopek, Alicja, Hu, May Khei, Gallacher, Peter J., Dear, James W., Borooah, Shyamanga, MacIntyre, Iain M., Pearson, Tom M.C., Willox, Laura, Talwar, Dinesh, Tafflet, Muriel, Roubeix, Christophe, Sennlaub, Florian, Chandran, Siddharthan, Dhillon, Baljean, Webb, David J., Dhaun, Neeraj“…SB was supported by a Wellcome Trust funded clinical research fellowship from the Scottish Translational Medicine and Therapeutics Initiative, and by a Rowling Scholarship, at the time of this work. …”
Publicado 2016
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145852por Evans, Malkanthi, Guthrie, Najla, Pezzullo, John, Sanli, Toran, Fielding, Roger A., Bellamine, Aouatef“…The combination showed an increase in mTOR protein level, a driver for increased muscle mass which translated to an improvement in muscle strength. This new combination may provide a potential nutritional intervention to promote muscle growth and improved physical functioning in older adults. …”
Publicado 2017
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145853“…Interestingly, these proteins were involved in a series of biological processes from gene expression to translation, suggesting that lowering these processes may contribute to improved heat resistance in sweet maize. …”
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145854por Hamblin, Angela, Wordsworth, Sarah, Fermont, Jilles M., Page, Suzanne, Kaur, Kulvinder, Camps, Carme, Kaisaki, Pamela, Gupta, Avinash, Talbot, Denis, Middleton, Mark, Henderson, Shirley, Cutts, Anthony, Vavoulis, Dimitrios V., Housby, Nick, Tomlinson, Ian, Taylor, Jenny C., Schuh, Anna“…Advances in sequencing technology, collectively referred to as next generation sequencing (NGS), mean the entire cancer genome or parts of it can now be sequenced at speed with increased depth and sensitivity. However, translation of NGS into routine cancer care has been slow. …”
Publicado 2017
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145855“…Although the Health Information Technology for Economic and Clinical Health (HITECH) act was responsible for a substantial infusion of capital into the EHR marketplace, the lack of a corporate entity in most F/OSS EHR projects translates to a marginal capacity to market the respective F/OSS system and to navigate certification. …”
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145856por Poça, Katia S., Parente, Thiago E. M., Chagas, Lucas F., Leal, Bruna S., Leal, Hellen S., Paumgartten, Francisco J. R., De-Oliveira, Ana C. A. X.“…Results therefore suggested that interstrain differences in constitutive activity of Cyp2a5 possibly arise from distinct translation efficiencies, protein half-lives and/or enzyme kinetics toward the substrate. …”
Publicado 2017
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145857por Lim, Jia Pei, Shyamasundar, Sukanya, Gunaratne, Jayantha, Scully, Olivia Jane, Matsumoto, Ken, Bay, Boon Huat“…BACKGROUND: Y-box binding protein-1 is an evolutionary conserved transcription and translation regulating protein that is overexpressed in various human malignancies, including breast cancer. …”
Publicado 2017
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145858por Sun, Min, Song, Haibin, Wang, Shuyi, Zhang, Chunxiao, Zheng, Liang, Chen, Fangfang, Shi, Dongdong, Chen, Yuanyuan, Yang, Chaogang, Xiang, Zhenxian, Liu, Qing, Wei, Chen, Xiong, Bin“…BACKGROUND: With persistent inconsistencies in colorectal cancer (CRC) miRNAs expression data, it is crucial to shift toward inclusion of a “pre-laboratory” integrated analysis to expedite effective precision medicine and translational research. Aberrant expression of hsa-miRNA-195 (miR-195) which is distinguished as a clinically noteworthy miRNA has previously been observed in multiple cancers, yet its role in CRC remains unclear. …”
Publicado 2017
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145859“…User expectations regarding developer responsiveness to their needs has implications for community-based participatory research and integrated knowledge translation. However, this expectation is incompatible with current mHealth funding structures.…”
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145860por Burke, Louise M., Ross, Megan L., Garvican‐Lewis, Laura A., Welvaert, Marijke, Heikura, Ida A., Forbes, Sara G., Mirtschin, Joanne G., Cato, Louise E., Strobel, Nicki, Sharma, Avish P., Hawley, John A.“…The increased rates of fat oxidation result in reduced economy (increased oxygen demand for a given speed) at velocities that translate to real‐life race performance in elite race walkers. …”
Publicado 2017
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