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  1. 146161
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    Circulating tumor DNA predicts neoadjuvant immunotherapy efficacy and recurrence-free survival in surgical non-small cell lung cancer patients
  2. 146162
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    Sleeve resection after neoadjuvant chemoimmunotherapy in the treatment of locally advanced non-small cell lung cancer
  3. 146163
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    Sphingosine 1-phosphate receptor 1 governs endothelial barrier function and angiogenesis by upregulating endoglin signaling
  4. 146164
    “…CONCLUSIONS AND RELEVANCE: In this cohort study, overweight in midlife, compared with normal BMI, was associated with higher cumulative burden of morbidity and greater proportion of life lived with morbidity in the context of similar longevity. These findings translated to higher total health care expenditures in older adulthood for those who were overweight in midlife.…”
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    Association of Body Mass Index in Midlife With Morbidity Burden in Older Adulthood and Longevity
  5. 146165
    por Skibba, Kathryn, Bell, Derek
    Publicado 2022
    “…Our results are likely restricted to large burn wounds and may not translate to smaller treatment areas. The increased operative productivity with ASCS assists in reduction of the technology unit cost. …”
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    799 Autologous Skin Cell Suspension Versus Standard Split Thickness Autografting: a Comparison of Operative Efficiency
  6. 146166
    “…The aim of this current translational research study was to assess the clinical relevance of liquid biopsy in 47 patients receiving osimertinib. …”
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    Effect of Osimertinib on CTCs and ctDNA in EGFR Mutant Non-Small Cell Lung Cancer Patients: The Prognostic Relevance of Liquid Biopsy
  7. 146167
    “…The results suggest that CAR cell IS quality can be used as a potential composite biomarker and correlates with antitumor activities in patients, which is sufficiently discriminative to further test the CAR IS quality as a clinical biomarker to predict response to CAR immunotherapy in cancer. For translational research, the method developed here can also provide guidelines for designing and optimizing numerous CAR constructs for potential clinical development. …”
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    In vitro machine learning-based CAR T immunological synapse quality measurements correlate with patient clinical outcomes
  8. 146168
    “…The present study explored the effect of low dose 10 μg/mL PTX (therapeutic dose) compared to high dose 300 μg/mL PTX (experimental dose) in RAW 264.7 cells through immunoprecipitation-based high performance liquid chromatography (IP-HPLC), immunohistochemistry, and western blot. 10 μg/mL PTX increased the expression of proliferation (Ki-67, PCNA, cyclin D2, cdc25A), epigenetic modification (KDM4D, PCAF, HMGB1), protein translation (DOHH, DHPS, eIF5A1), RAS signaling (KRAS, pAKT1/2/3, PI3K), NFkB signaling (NFkB, GADD45, p38), protection (HSP70, SOD1, GSTO1/2), survival (pAKT1/2/3, SP1, sirtuin 6), neuromuscular differentiation (NSEγ, myosin-1a, desmin), osteoblastic differentiation (BMP2, RUNX2, osterix), acute inflammation (TNFα, IL-1, CXCR4), innate immunity (β-defensin 1, lactoferrin, TLR-3, -4), cell-mediated immunity (CD4, CD8, CD80), while decreased the expression of ER stress (eIF2α, eIF2AK3, ATF6α), fibrosis (FGF2, CTGF, collagen 3A1), and chronic inflammation (CD68, MMP-2, -3, COX2) versus the untreated controls. …”
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    Pentoxifylline-induced protein expression change in RAW 264.7 cells as determined by immunoprecipitation-based high performance liquid chromatography
  9. 146169
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    Development and validation of an algorithm using health administrative data to define patient attachment to primary care providers
  10. 146170
    “…We also developed a decision analytic Markov model that forecasts the mobility of recipients beyond the 24-month follow-up of the trial and translated this into future costs and potential benefit to health-related quality of life using the National Health Service and Personal Social Services perspective. …”
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    Cost-effectiveness of a physical activity and behaviour maintenance programme on functional mobility decline in older adults: an economic evaluation of the REACT (Retirement in Action) trial
  11. 146171
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    Rate and risk factors of recurrent immune checkpoint inhibitor-related pneumonitis in patients with lung cancer
  12. 146172
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    Positive lymph node ratio predicts adverse prognosis for patients with lymph nodes metastatic hypopharyngeal squamous cell carcinoma after primary surgery
  13. 146173
    “…The proximal tibia was fixed only in the vertical direction, allowing it to translate and rotate in all other degrees of freedom. …”
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    Ability of the Posterior Tibial Tendon to Restore Foot Alignment in Progressive Collapsing Foot Deformity: A Computational Study
  14. 146174
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    Out-of-pocket medical expenditure and associated factors of advanced colorectal cancer in China: a multi-center cross-sectional study
  15. 146175
    “…Moreover, the prevalence of GAS desire was higher among patients with GD (aPR 1.09; 95% CI: 1.01–1.18; P value = .03) than individuals without GD. CLINICAL TRANSLATION: Providers' awareness of patients’ desires, values, and health-seeking preferences could facilitate differentiated guidance on their gender affirmation. …”
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    Prevalence and Factors Associated With Gender-Affirming Surgery Among Transgender Women & Transgender Men in a Community-Based Clinic in Metro Manila, Philippines: A Retrospective Study
  16. 146176
    “…BACKGROUND: People with gestational diabetes have enhanced learning requirements during pregnancy, and management of their disease often requires the translation of health information into new health behavior changes. …”
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    Content Quality of YouTube Videos About Gestational Diabetes: Systematic Evaluation
  17. 146177
    por Song, Juan
    Publicado 2022
    “…The teaching contents include 22 listening modules, 20 reading modules, 23 cloze modules, 24 translation modules, and 22 speaking modules. Overall, students' English learning level has been greatly improved. (2) Generally speaking, the overall reliability coefficient of the sample data with full English teaching content is mostly kept in the range of 0.70–0.95, and only a few parts show a low situation, which also shows the overall situation of the diversity of teaching content. …”
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    English Teaching Quality Monitoring and Multidimensional Analysis Based on the Internet of Things and Deep Learning Model
  18. 146178
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    Clinicopathologic characteristics and diagnostic methods of RET rearrangement in Chinese non-small cell lung cancer patients
  19. 146179
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    A combination of the APACHE II score, neutrophil/lymphocyte ratio, and expired tidal volume could predict non-invasive ventilation failure in pneumonia-induced mild to moderate acute respiratory distress syndrome patients
  20. 146180
    “…FUNDING: Chinese Academy of Medical Sciences (CAMS) Initiative for Innovative Medicine (CAMS 2021-I2M-1-010), National Key R&D Program of China (grant no 2017YFC1309400), and National Natural Science Foundation of China (grant no 81720108001). NOTE: Chinese translation of abstract is available in appendix section.…”
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    Prevalence of tobacco dependence and associated factors in China: Findings from nationwide China Health Literacy Survey during 2018–19
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