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146381por Han, Wenjing, Yang, Feng, Wu, Zhihong, Guo, Fuqiang, Zhang, Junjie, Hai, Erhan, Shang, Fangzheng, Su, Rui, Wang, Ruijun, Wang, Zhiying, Liu, Zhihong, Zhao, Yanhong, Wang, Zhixin, Zhang, Yanjun, Li, Jinquan“…It was verified that chi-miR-199a-5p inhibited TGF-β2 expression at both mRNA and protein translation levels in fibroblasts. At the same time, it was again proved that the TGF-β2 gene is a target gene of chi-miR199a-5p.…”
Publicado 2020
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146382Pharmacokinetics, radiation dosimetry, acute toxicity and automated synthesis of [(18)F]AmBF(3)-TATEpor Lau, Joseph, Pan, Jinhe, Rousseau, Etienne, Uribe, Carlos F., Seelam, Sudhakara Reddy, Sutherland, Brent W., Perrin, David M., Lin, Kuo-Shyan, Bénard, François“…INTRODUCTION: [(18)F]AmBF(3)-TATE is a somatostatin agonist that selectively binds to somatostatin receptor subtype 2 (SSTR2). For clinical translation, pharmacokinetics, radiation dosimetry, and acute toxicity of [(18)F]AmBF(3)-TATE were assessed with good laboratory practice (GLP) standards. …”
Publicado 2020
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146383por Abraham, Rachy, Mudaliar, Prashant, Jaleel, Abdul, Srikanth, Jandhyam, Sreekumar, Easwaran“…Proteins involved in transcription, translation, apoptosis and stress response were the major ones among the 209 proteins that had significant up-regulation. …”
Publicado 2015
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146384por Bustin, Aurélien, Rashid, Imran, Cruz, Gastao, Hajhosseiny, Reza, Correia, Teresa, Neji, Radhouene, Rajani, Ronak, Ismail, Tevfik F., Botnar, René M., Prieto, Claudia“…Vessel sharpness, vessel length and image quality obtained with the proposed non-rigid (NR) PROST approach were compared against translational correction only (TC-PROST) and a previously proposed NR motion-compensated technique (non-rigid SENSE) in healthy subjects. …”
Publicado 2020
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146385por Arbabisarjou, Azizollah, Akbarilakeh, Maryam, Soroush, Fatemeh, Payandeh, Abolfazl“…In order to carry out this study, Grasha–Riechmann Teaching Style Inventory was translated and culturally adopted. To measure validity, reliability, and normalize the questionnaire, it was distributed among the study population composed of 361 faculty members (instructor, assistant professor, associate professor, and professor) who were taught theoretical and practical courses in Zahedan University of Medical Sciences, Zahedan, Iran, during the academic year 2018–2019. …”
Publicado 2020
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146386por Fovet, T., Lancelevée, C., Eck, M., Scouflaire, T., Bécache, E., Dandelot, D., Giravalli, P., Guillard, A., Horrach, P., Lacambre, M., Lefebvre, T., Moncany, A.-H., Touitou, D., David, M., Thomas, P.“…METHODS: This work is based on a survey conducted in April 2020 in France among psychiatric healthcare providers working in 42 ambulatory units for inmates and in the 9 full-time inpatient psychiatric wards exclusively for inmates called “UHSAs” (which stands for “unités hospitalières spécialement aménagées”, and can be translated as “specially equipped hospital units”). …”
Publicado 2020
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146387por Canton, Ana Pinheiro-Machado, Krepischi, Ana, Montenegro, Luciana Ribeiro, Costa, Silvia, Rosenberg, Carla, Ramos, Carolina, Faria, Aline Guimarães, Seraphim, Carlos Eduardo, Tinano, Flávia Rezende, Kawahira, Rachel, Kim, Chong, de Zegher, Francis Edouard, de Assis Funari, Mariana Ferreira, Jorge, Alexander Augusto Lima, Mendonca, Berenice Bilharinho, Brito, Vinicius Nahime, Latronico, Ana Claudia“…Defects in sporadic cases were as follows: three cases with 7q11.23 deletion (Williams syndrome); one girl with ventricular arrhythmia presenting a rare 1p31.3 duplication, involving NFIA gene coding a transcription factor of NFI family with hypothalamic expression; and one girl with imperforate anus and learning difficulties with rare frameshift variants in AREL1 gene (p.Ser229Aspfs*3) coding an ubiquitin ligase, and TNRC6B gene (p.Gly665Leufs*35) coding a regulator of translational inhibition. In the four familial cases, the genetic defects segregated with CPP in a dominant inheritance mode. …”
Publicado 2020
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146388por Moreira, Ana Rita Silva, Lagasse, Alexandra N, Haney, Anessa C, Avaritt, Nathan, Byrum, Stephanie, Boehm, Ulrich, Kharas, Michael G, Lengner, Christopher J, MacNicol, Melanie C, Childs, Gwen V, MacNicol, Angus M, Odle, Angela Katherine“…We showed that MSI binds to Gnrhr and inhibits translation, and a gonadotrope-specific deletion of Msi1 and Msi2 (Gon-Msi1/2-null) leads to increased GnRHR protein levels. …”
Publicado 2020
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146389“…BACKGROUND: Pumilio RNA-binding proteins are evolutionarily conserved throughout eukaryotes and are involved in RNA decay, transport, and translation repression in the cytoplasm. Although a majority of Pumilio proteins function in the cytoplasm, two nucleolar forms have been reported to have a function in rRNA processing in Arabidopsis. …”
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146390por Oliffe, John L, Black, Nick, Yiu, Jeffrey, Flannigan, Ryan K, McCreary, Donald R, Goldenberg, S Larry“…Relatedly, mapping of behavior changes using health promotion theories including the transtheoretical model (or stages of change) has been recommended to build a translatable empirical base to advance design and evaluation considerations for men’s eHealth programs. …”
Publicado 2020
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146391por Dunbar, Richard L., Gaudet, Daniel, Davidson, Michael, Rensfeldt, Martin, Yang, Hong, Nilsson, Catarina, Kvarnström, Mats, Oscarsson, Jan“…It is not clear why the greater 24-h exposure of OM3-CA versus OM3-EE observed with a low-fat meal did not translate into significantly higher pre-dose fasting levels of DHA + EPA with longer-term use. …”
Publicado 2020
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146392por Atukunda, Esther C, Mugyenyi, Godfrey R, Obua, Celestino, Musiimenta, Angella, Najjuma, Josephine N, Agaba, Edgar, Ware, Norma C, Matthews, Lynn T“…Interviews were conducted and digitally recorded in a private setting by a trained native speaker to elicit experiences of pregnancy and birth. Translated transcripts were generated and coded. Coded data were iteratively reviewed and sorted to derive descriptive categories using an inductive content analytic approach. …”
Publicado 2020
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146393por Vaillancourt, Christian, Charette, Manya, Taljaard, Monica, Thavorn, Kednapa, Hall, Elizabeth, McLeod, Brent, Fergusson, Dean, Brehaut, Jamie, Graham, Ian, Calder, Lisa, Ramsay, Tim, Tugwell, Peter, Kelly, Peter, Cheskes, Sheldon, Saskin, Refik, Plint, Amy, Osmond, Martin, Macarthur, Colin, Straus, Sharon, Rochon, Paula, Prud'homme, Denis, Dahrouge, Simone, Marlin, Susan, Stiell, Ian G“…Our 36-month study will consist of a 12-month setup and training period (year 1), followed by the stepped-wedge trial (year 2) and a 12-month period for study completion, analyses, and knowledge translation. A total of 12 Ontario paramedic services of various sizes distributed across the province will be randomly allocated to one of three sequences. …”
Publicado 2020
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146394por Gogue, Christelle, Wagman, Joseph, Tynuv, Kenzie, Saibu, Andrew, Yihdego, Yemane, Malm, Keziah, Mohamed, Wahjib, Akplu, Welbeck, Tagoe, Titus, Ofosu, Anthony, Williams, Ignatius, Asiedu, Samuel, Richardson, Jason, Fornadel, Christen, Slutsker, Laurence, Robertson, Molly“…RESULTS: District-level analysis from Northern Region from 2015 to 2017 of the aggregate malaria incidence reported from IRS districts relative to non-IRS comparator districts showed 39%, 26%, and 58% fewer confirmed malaria cases reported from IRS districts in 2015, 2016, and 2017, respectively. This translates to approximately 257,000 fewer cases than expected over the three years. …”
Publicado 2020
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146395por Suelo-Calanao, Rona Lee, Thomson, Richard, Read, Maxine, Matheson, Euan, Isaac, Emmanuel, Chaudhry, Mubarak, Loubani, Mahmoud“…This however did not translate into shorter hospital stay or mortality.…”
Publicado 2020
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146396por Archambault, Patrick Michel, Rivard, Josée, Smith, Pascal Y, Sinha, Samir, Morin, Michèle, LeBlanc, Annie, Couturier, Yves, Pelletier, Isabelle, Ghandour, El Kebir, Légaré, France, Denis, Jean-Louis, Melady, Don, Paré, Daniel, Chouinard, Josée, Kroon, Chantal, Huot-Lavoie, Maxime, Bert, Laetitia, Witteman, Holly O, Brousseau, Audrey-Anne, Dallaire, Clémence, Sirois, Marie-Josée, Émond, Marcel, Fleet, Richard, Chandavong, Sam“…CONCLUSIONS: This study will provide evidence on effective knowledge translation strategies to adapt best practices to the local context in the transition of care for elderly people. …”
Publicado 2020
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146397por Herrera-Rios, Dayana, Li, Guanzhang, Khan, Dilaware, Tsiampali, Julia, Nickel, Ann-Christin, Aretz, Philippe, Hewera, Michael, Suwala, Abiagail Kora, Jiang, Tao, Steiger, Hans-Jakob, Kamp, Marcel Alexander, Muhammad, Sajjad, Hänggi, Daniel, Maciaczyk, Jarek, Zhang, Wei, Kahlert, Ulf Dietrich“…However, the clinical translation remains challenging due to severe toxicity side effects and emergence of therapy resistance. …”
Publicado 2020
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146398por Mollaioli, Daniele, Sansone, Andrea, Ciocca, Giacomo, Limoncin, Erika, Colonnello, Elena, Di Lorenzo, Giorgio, Jannini, Emmanuele A.“…Structural equation modeling evidenced the protective role of sexual activity toward psychological distress (β(males) = -0.18 and β(females) = -0.14), relational health (β(males) = 0.26 and β(females) = 0.29) and sexual health, both directly (β(males) = 0.43 and β(females) = 0.31), and indirectly (β(males) = 0.13 and β(females) = 0.13). CLINICAL TRANSLATION: The demonstrated mutual influence of sexual health on psychological and relational health could direct the clinical community toward a reinterpretation of the relationship among these factors. …”
Publicado 2020
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146399por Avolio, Alfonso W., Franco, Antonio, Schlegel, Andrea, Lai, Quirino, Meli, Sonia, Burra, Patrizia, Patrono, Damiano, Ravaioli, Matteo, Bassi, Domenico, Ferla, Fabio, Pagano, Duilio, Violi, Paola, Camagni, Stefania, Dondossola, Daniele, Montalti, Roberto, Alrawashdeh, Wasfi, Vitale, Alessandro, Teofili, Luciana, Spoletini, Gabriele, Magistri, Paolo, Bongini, Marco, Rossi, Massimo, Mazzaferro, Vincenzo, Di Benedetto, Fabrizio, Hammond, John, Vivarelli, Marco, Agnes, Salvatore, Colledan, Michele, Carraro, Amedeo, Cescon, Matteo, De Carlis, Luciano, Caccamo, Lucio, Gruttadauria, Salvatore, Muiesan, Paolo, Cillo, Umberto, Romagnoli, Renato, De Simone, Paolo“…The EASE score may be used in translational research across transplant centers.…”
Publicado 2020
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146400“…This indicated that faster rates of translation (as achieved through codon optimization) could overcome the control exercised by these segments. …”
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