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  1. 146421
    “…CONCLUSIONS: Very few AI-based health analytics have been translated from algorithm to real-world use. This study will use robust, prospective, randomized controlled, clinical trial methodology to assess the effectiveness of an advanced AI predictive analytics monitoring system in incorporating real-time telemetric data for identifying clinical deterioration on acute care wards. …”
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    Predictive Monitoring–Impact in Acute Care Cardiology Trial (PM-IMPACCT): Protocol for a Randomized Controlled Trial
  2. 146422
    “…The components of the NP-NHC delivery system are already used in FDA approved formulations, which will facilitate clinical translation.…”
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    3: IGF-1 Hydrogel-based Nanofiber Drug Delivery System to Improve Nerve Regeneration and Functional Recovery After Peripheral Nerve Repair
  3. 146423
    “…Blood type A patients had a higher propensity of kidney injury, but this did not translate into worse in-hospital survival. DISCLOSURES: Cohen:GBT: Speakers Bureau.…”
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    Association of Blood Type on Clinical Outcomes in Black/African Americans Hospitalized for COVID-19 Infection
  4. 146424
    “…Changes in cell function, phenotype, and morphology in circulating leukocytes can be translated into numerical data obtained from an automated analyzer. …”
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    A Machine Learning Approach for the Differential Diagnosis between Sars-COV19 Infection and Influenza Viruses with Hematological Morphologic DATA (CELL MORPHOLOGIC DATA)
  5. 146425
    “…CITI demonstrates the important role of digital information and support platforms for translating evidence into practice and improving knowledge and reducing stigma.…”
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    Online Artículo Texto
    Evaluation of a Digital Health Initiative in Illicit Substance Use: Cross-sectional Survey Study
  6. 146426
    “…A questionnaire to measure self-confidence in fundoscopy technique assessing optic nerve, cup-to-disc ratio and macula was translated and validated to Portuguese, and applied 1-month and 1-year after practical training. …”
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    Comparison of conventional and wide field direct ophthalmoscopy on medical students’ self-confidence for fundus examination: a 1-year follow-up
  7. 146427
    “…The FEEDS Project is being implemented in five phases: participatory project planning, digital climate change platform customization, community-led evaluation, digital platform and project refinement, and integrated knowledge translation. The project is governed by a Citizen Scientist Advisory Council comprising Elders, Traditional Knowledge Keepers, key community decision makers, youth, and FEEDS Project researchers. …”
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    The Food Equity and Environmental Data Sovereignty (FEEDS) Project: Protocol for a Quasi-Experimental Study Evaluating a Digital Platform for Climate Change Preparedness
  8. 146428
    “…However, more studies are encouraged to provide more robust evidence to translate circRNAs into clinical practice. TRIAL REGISTRATION: PROSPERO ID: CRD42021235031 SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13018-021-02568-2.…”
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    Clinicopathologic significance and prognostic value of circRNAs in osteosarcoma: a systematic review and meta-analysis
  9. 146429
    “…Nevertheless, a clear disconnect exists between its mRNA and protein levels, indicating that its post-translational regulation may be critical in maintaining its protein levels. …”
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    Reciprocal deregulation of NKX3.1 and AURKA axis in castration-resistant prostate cancer and NEPC models
  10. 146430
    “…Acutely, a single injection of Compound A in drug‐naïve mice had no effect on the rate of protein synthesis in skeletal muscle, as measured via the surface sensing of translation method, while the expression of Nr4a3 and Ppargc1a4 was increased (P < 0.05 vs. vehicle). …”
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    Modified UCN2 peptide treatment improves skeletal muscle mass and function in mouse models of obesity‐induced insulin resistance
  11. 146431
    “…This study highlights that MSC-EXO have high translational value in repairing cardiac dysfunction following infarction. …”
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    Hemin enhances the cardioprotective effects of mesenchymal stem cell-derived exosomes against infarction via amelioration of cardiomyocyte senescence
  12. 146432
    “…FINDINGS: There were 20 (13%) COVID-19-related deaths in patients with rare diseases (n=158) and five (4%) COVID-19-related deaths in unaffected relatives (n=125), translating to an increased risk of mortality in patients with rare diseases (OR 3·47 [95% CI 1·21–12·2], Fisher's exact p=0·011). …”
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    Increased COVID-19 related mortality rate for patients with rare diseases: a retrospective cohort study with data from Genomics England
  13. 146433
    “…Improvement in metabolic health may not translate into improved female fecundity. TRIAL REGISTRATION: ClinicalTrials.gov NCT02432209.…”
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    Effects of preconception lifestyle intervention in infertile women with obesity: The FIT-PLESE randomized controlled trial
  14. 146434
    “…Also, none of the CV restraints on CPET translated to provocation test anomalies. CONCLUSION: CV symptoms of Post-COVID are highly prevalent, but signify actual CV disease only in a minority of patients. …”
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    Cardio-COVID clinic – a one-center experience
  15. 146435
    “…Undiagnosed AF patients can develop complications that could potentially translate into poorer long-term outcomes. PURPOSE: In this scenario, we aimed to verify the impact of telemedicine (TLM) during lockdown, in comparison with the same period in 2019. …”
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    Impact of telemedicine network provided by local pharmacies in the management of symptomatic tachyarrhytmias during COVID-19 outbreak
  16. 146436
    “…CONCLUSIONS: HIV, TB, laboratory, MCH, and reporting to dhis-2 selected indicators were positively impacted by accreditation. This impact translated into increased health care services performance at the accredited facility as compared to the non-accredited facilities.…”
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    Impact of accreditation on health care services performance in Kiryandongo district, Uganda: a longitudinal study
  17. 146437
    “…CONCLUSIONS: This novel real-world analysis suggests a clinical benefit for therapy escalation to natalizumab versus fingolimod based on comparative effectiveness results, translating to higher QALYs and lower costs for UK patients inadequately responding to BRACETD. …”
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    Comparative Effectiveness and Cost-Effectiveness of Natalizumab and Fingolimod in Patients with Inadequate Response to Disease-Modifying Therapies in Relapsing-Remitting Multiple Sclerosis in the United Kingdom
  18. 146438
    “…The census model of continuous enrollment and real-time data availability offers a wider set of potential benefits, but at an initially higher cost and with the requirement for more substantial data translation and managerial capacity to make use of such data.…”
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    A Comparison of Census and Cohort Sampling Models for the Longitudinal Collection of User-Reported Data in the Maternity Care Pathway: Mixed Methods Study
  19. 146439
    “…Further research is warranted to determine if such intent translates into app use, and better symptom management and health care quality.…”
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    Understanding Patients’ Intention to Use Digital Health Apps That Support Postdischarge Symptom Monitoring by Providers Among Patients With Acute Coronary Syndrome: Survey Study
  20. 146440
    “…In addition, this nomogram was translated to a Web-based calculator that could generate individual probability for ARF in a visualized form. …”
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    A Nomogram for Predicting Acute Respiratory Failure After Cervical Traumatic Spinal Cord Injury Based on Admission Clinical Findings
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