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  1. 146601
    “…Current efforts to develop gene therapies to activate mammalian Müller glia for retinal repair will require safe and effective delivery strategies for recombinant adeno-associated viruses (AAVs), vectors of choice for clinical translation. Intravitreal and subretinal injections are currently used for AAV gene delivery in the eye, but less invasive methods efficiently targeting Müller glia have yet to be developed. …”
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  2. 146602
  3. 146603
  4. 146604
    por Plagemann, P. G. W.
    Publicado 1991
    “…Genomic RNA is probably translated into a single polyprotein of 3010/3011 amino acids which is processed into functional proteins. …”
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  5. 146605
    “…In the future, further construct and model fit validation and English translation with appropriate adaptation of this whole scale are required, so that this scale can be further validated and applied worldwide.…”
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  6. 146606
    “…We hypothesized that in placenta, the metabolic and nutrient sensor O-GlcNAc transferase (OGT), highly sensitive to glucose flux through the hexosamine biosynthetic pathway (HBP), responds to maternal obesogenic environment by increasing O-GlcNAc post-translational modification of nucleocytoplasmic proteins in the placenta altering fetal growth trajectories. …”
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  7. 146607
    “…UAG treatment (100nM) had no effect on GHSR1a-mediated Ca(2+) influx in the presence or absence of MP2. MP2 is post-translationally modified and we suspected this to be important for its activity. …”
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  8. 146608
    por Kelley, Carly, Coviello, Andrea D
    Publicado 2020
    “…Larger, prospective studies are needed to determine whether these changes persist over the longer duration of CSHT and whether this translates to an increased risk of cardiovascular disease and mortality. …”
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  9. 146609
  10. 146610
  11. 146611
  12. 146612
  13. 146613
    “…The effect of selective head-neck cooling on physiological and cognitive functions in healthy volunteers. Jackson et al. Translational Neuroscience (2015) 6:131. 4. Neurobiological effect of selective brain cooling after concussive injury. …”
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  14. 146614
    “…S-acylation is a dynamic post-translational modification that modulates hydrophobicity of proteins, regulating their membrane association and subcellular localization. …”
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  15. 146615
  16. 146616
  17. 146617
    “…This is complemented by qualitative research findings that poor quality of care during delivery and immediate postpartum related to: work related burnout, gap between providers’ skill and knowledge, lack of enabling working environment, poor motivation scheme and issues related to retention, poor providers caring behavior, unable translate training into practice, mismatch between number of provider and facility client flow for delivery, and in availability of essential medicine and supplies. …”
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  18. 146618
  19. 146619
  20. 146620
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