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  1. 146801
    “…Both miR-130a and miR-130b might only inhibit Cx43 translation or degrade Cx43 proteins and did not affect Cx43 mRNA stability. …”
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    BCR-ABL1-driven exosome-miR130b-3p-mediated gap-junction Cx43 MSC intercellular communications imply therapies of leukemic subclonal evolution
  2. 146802
    “…However, other markers did not show significant changes (e.g., mRNA levels of TNFR-1, WFDC2, B2M, likely due to factors influencing their half-life and translation rate). To explore treatments, we tested a drug called SPIKENET (SPK), a 15-amino acid synthetic peptide, that blocks the virus from attaching and entering cells. …”
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    Kidney Damage in Long COVID: Studies in Experimental Mice
  3. 146803
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    Metal-on-metal (MoM) hip implants and pregnancy: are MoM implants good for mom?—a systematic review
  4. 146804
    “…Web-based delivery promises to improve insomnia, particularly for rural caregivers who have limited access to traditional in-person treatments. Our team translated an efficacious 4-session standard CBT-I content protocol into digital format to create NiteCAPP. …”
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    Development and Initial Evaluation of Web-Based Cognitive Behavioral Therapy for Insomnia in Rural Family Caregivers of People With Dementia (NiteCAPP): Mixed Methods Study
  5. 146805
    “…In this study, we collected 117 Salmonella isolates from diseased chickens in Sichuan Province of China from 2019 to 2021, and investigated antimicrobial resistance (AMR) patterns, including extended spectrum β-lactamase (ESBL) resistance, the prevalence and con-translation of ESBL and virulence genes, and sequence type (ST) among these isolates. …”
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    Association between Phenotypes of Antimicrobial Resistance, ESBL Resistance Genes, and Virulence Genes of Salmonella Isolated from Chickens in Sichuan, China
  6. 146806
    “…Stronger albumin-binding properties translated into enhanced blood residence of the respective folate radioconjugates, while the blood circulation time was found to be inversely linked to the radioconjugates’ renal accumulation. …”
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    Investigations Using Albumin Binders to Modify the Tissue Distribution Profile of Radiopharmaceuticals Exemplified with Folate Radioconjugates
  7. 146807
    “…Although this mutation occurs in the 3′-UnTranslated Region, it represents the first example of exonic polymorphism in the CSN1S2 for this species. …”
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    Sequencing and Characterization of αs2-Casein Gene (CSN1S2) in the Old-World Camels Have Proven Genetic Variations Useful for the Understanding of Species Diversification
  8. 146808
    “…The main results are the high levels of patient inclusion in clinical trials and locoregional treatments of metastasis, that translate in a benefit in survival, together with the absence of significant differences in the magnitude of benefit from non molecularly driven use of various TKI in later lines since the introduction of imatinib. …”
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    Evolution of Patterns of Care and Outcomes in the Real-Life Setting for Patients with Metastatic GIST Treated in Three French Expert Centers over Three Decades
  9. 146809
    por Zuberbier, Torsten, Abdul Latiff, Amir, Aggelidis, Xenofon, Augustin, Matthias, Balan, Radu‐Gheorghe, Bangert, Christine, Beck, Lisa, Bieber, Thomas, Bernstein, Jonathan A., Bertolin Colilla, Marta, Berardi, Alejandro, Bedbrook, Anna, Bindslev‐Jensen, Carsten, Bousquet, Jean, de Bruin‐Weller, Marjolein, Bruscky, Dayanne, Buyuktiryaki, Betul, Canonica, Giorgio Walter, Castro, Carla, Chanturidze, Natia, Chong‐Neto, Herberto Jose, Chu, Chia‐Yu, Chularojanamontri, Leena, Cork, Michael, Criado, Roberta F. J., Barredo, Laia Curto, Custovic, Adnan, Darsow, Ulf, Emurlai, Arben, de Pablo, Ana, Del Giacco, Stefano, Girolomoni, Giampiero, Deleva Jovanova, Tanja, Deleuran, Mette, Douladiris, Nikolaos, Duarte, Bruno, Dubakiene, Ruta, Eller, Esben, Engel‐Yeger, Batya, Ensina, Luis Felipe, Filho, Nelson Rosario, Flohr, Carsten, Fomina, Daria, Francuzik, Wojciech, Galimberti, Maria Laura, Giménez‐Arnau, Ana M., Godse, Kiran, Mortz, Charlotte Gotthard, Gotua, Maia, Hide, Michihiro, Hoetzenecker, Wolfram, Hunzelmann, Nicolas, Irvine, Alan, Jack, Carolyn, Kanavarou, Ioanna, Katoh, Norito, Kinaciyan, Tamar, Kocatürk, Emek, Kulthanan, Kanokvalai, Lapeere, Hilde, Lau, Susanne, Machado Forti Nastri, Mariana, Makris, Michael, Mansour, Eli, Marsland, Alexander, Morelo Rocha Felix, Mara, Moschione Castro, Ana Paula, Nettis, Eustachio, Nicolas, J. F., Nosbaum, Audrey, Odemyr, Mikaela, Papapostolou, Niki, Parisi, Claudio A. S., Paudel, Sushil, Peter, Jonny, Pokharel, Prakash, Puig, Luis, Quint, Tamara, Ramon, German Dario, Regateiro, Frederico, Ricci, Giampaolo, Rosario, Cristine, Sackesen, Cansin, Schmid‐Grendelmeier, Peter, Serra‐Baldrich, Esther, Siemens, Kristina, Smith, Cathrine, Staubach, Petra, Stevanovic, Katarina, Su‐Kücük, Özlem, Sussman, Gordon, Tavecchio, Simona, Teovska Mitrevska, Natasa, Thaci, Diamant, Toubi, Elias, Traidl‐Hoffmann, Claudia, Treudler, Regina, Vadasz, Zahava, van Hofman, Ingrid, Ventura, Maria Teresa, Wang, Zhao, Werfel, Thomas, Wollenberg, Andreas, Yang, Ariana, Weng Yew, Yik, Zhao, Zuotao, Zwiener, Ricardo, Worm, Margitta
    Publicado 2023
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    A concept for integrated care pathways for atopic dermatitis—A GA(2)LEN ADCARE initiative
  10. 146810
    “…Study confirms hyperglycemia and hypoalbuminemia with composite exposure cut point details as traits that may shape host response to SARS-CoV-2 infection. Translational implications suggest value of serial tracking of SG and SA levels as a simple available gauge of COVID-19 progression severity. …”
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    THU332 Composite Glucose And Albumin Biomarker Tool Provides Strong Mortality Risk Assessment At Presentation And Throughout Index COVID-19 Hospitalization
  11. 146811
    “…These regulators bind to 3'-untranslated region (3'-UTR) of MR transcripts to modulate their stability and translation. Therefore, we hypothesized that these miRNAs may be responsible for low expression level of MR at birth, where variations in tonicity are observed due to the transition from intra-amniotic to extra-uterine life. …”
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    FRI163 Central Role Of Mirnas During Kidney Development And Establishment Of The Mineralocorticoid Signaling Pathway Establishment Of The Mineralocorticoid Signaling Pathway
  12. 146812
    “…Herein, we comprehensively examine the translational potential of intranasal kisspeptin administration for the first time using a series of human, rodent and pharmaceutical studies. …”
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    OR17-06 Clinical And Mechanistic Insight For The Therapeutic Potential Of Intranasal Kisspeptin Administration To Treat Reproductive Disorders In Humans
  13. 146813
    “…By gene set enrichment analysis, control and PIC-treated female islets were enriched in differentiation and development pathways, while male islets were enriched in protein translation and steroid metabolism. To probe the role of sex steroid signaling in islet inflammatory response, we measured expression of Esr1 (encoding ERa) via qRT-PCR in mouse islets in response to PIC (IFNy, IL-1b, TNFa). …”
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    FRI613 Sex Differences In Human Islet Transcriptional Responses To Inflammation
  14. 146814
    “…Background: Previous studies in transgender individuals have shown that masculinizing (testosterone) hormone therapy increases and feminizing (estradiol combined with anti-androgen) hormone therapy decreases serum creatinine. Translating this into estimated glomerular filtration rate (eGFR) according to the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation, eGFR increases in transwomen and decreases in transmen during gender-affirming hormone therapy (GAHT). …”
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    OR31-06 Gender-Affirming Hormone Therapy Affects Serum Cystatin C-based eGFR In Transgender Individuals
  15. 146815
    “…MicroRNAs (miRNAs) inhibit translation of specific mRNAs; thus, this study aimed to understand the involvement of miRNAs in the regulation of insulin signaling and resistance in hypothalamic neurons. …”
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    SAT047 Regulation Of The Insulin Receptor And The Insulin-like Growth Factor 1 Receptor By miR-322-5p, A miR-16 Family Member, In Hypothalamic Neuronal Models
  16. 146816
    “…Results: In cell-based assays, HS235 potently and selectively neutralized activins and GDFs implicated in body composition. This translated to complete in vivo target engagement and pharmacodynamic response. …”
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    FRI017 Precision-engineered Activin And GDF Ligand Trap HS235: A Novel Lean Mass-preserving Treatment for Obesity
  17. 146817
    “…However, it is uncertain whether this association of FSH elevation and bone loss translates to increased fracture risk. To examine the relationship between FSH and incident hip fracture, independent of sex hormone levels, we used a case-cohort design to sample from the AGES-Reykjavik cohort, a longitudinal cohort of 5764 older Icelandic adults designed to assess gene/environment interactions and their relationship to diseases in old age. …”
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    FRI675 Higher FSH Level Is Associated With Increased Risk Of Incident Hip Fracture In Older Adults, Independent Of Sex Hormone Levels
  18. 146818
    Publicado 2022
    “…The concept of ‘public health’ began to be used in earnest in 1890, when Ogai Mori(1862-1922) translated Western-style health protection measures for the public as public health. …”
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    근대 동아시아 위생 개념의 확산과 공공의료 담론의 형성(†)
  19. 146819
    “…Searches were limited to evidence published or translated in English. Two independent reviewers conducted title and abstract screening, and potentially relevant results were retrieved in full. …”
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    Exploring current nutritional programming and resources available to people living with HIV in Canada: a scoping review
  20. 146820
    “…Based on the preclinical results, [(99m)Tc]Tc-N(4)-L6-CPCR4 ([(99m)Tc]Tc-PentixaTec) was selected for an early translation to the human setting. Five patients with hematologic malignancies underwent [(99m)Tc]Tc-N(4)-L6-CPCR4 SPECT/planar imaging with individual dosimetry. …”
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    [(99m)Tc]Tc-PentixaTec: development, extensive pre-clinical evaluation, and first human experience
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