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147081por Mugwanya, Kenneth K., Hendrix, Craig W., Mugo, Nelly R., Marzinke, Mark, Katabira, Elly T., Ngure, Kenneth, Semiyaga, Nulu B., John-Stewart, Grace, Muwonge, Timothy R., Muthuri, Gabriel, Stergachis, Andy, Celum, Connie L., Baeten, Jared M.“…The estimated equivalent doses an infant would ingest daily from breastfeeding were 0.47 μg/kg (IQR 0.35 to 0.71) for tenofovir and 31.9 μg/kg (IQR 21.0 to 60.8) for emtricitabine, translating into a <0.01% and 0.5% relative dose when compared to the 6 mg/kg dose that is proposed for therapeutic treatment of infant HIV infection and for prevention of infant postnatal HIV infection; a dose that has not shown safety concerns. …”
Publicado 2016
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147082por Nair, Navya, Camacho-Vanegas, Olga, Rykunov, Dmitry, Dashkoff, Matthew, Camacho, Sandra Catalina, Schumacher, Cassie A., Irish, Jonathan C., Harkins, Timothy T., Freeman, Elijah, Garcia, Isaac, Pereira, Elena, Kendall, Sviatoslav, Belfer, Rachel, Kalir, Tamara, Sebra, Robert, Reva, Boris, Dottino, Peter, Martignetti, John A.“…However, our findings suggest that further insight into development of cancer or its interruption are needed before translation to the clinic.…”
Publicado 2016
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147083por Hébert-Losier, Kim, Zinner, Christoph, Platt, Simon, Stöggl, Thomas, Holmberg, Hans-Christer“…A certain strength level is required, although more does not necessarily translate to superior sprint skiing performance, and sufficient strength-endurance capacities are also of importance to minimize the impact and accumulation of fatigue during repeated heats. …”
Publicado 2016
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147084“…Novel aspects were audio recorded PPI discussions, which contributed qualitative data; first, to interpret systematic review findings and construct intervention vignettes for use in the qualitative research; second, to assist with recruitment to improve sample diversity in the formal qualitative dataset; and third, to translate theory and findings presented in a researcher generated logic model into a lay tool. …”
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147085por Cai, S., Natarajan, P., Chan, J.K.Y., Wong, P.C., Tan, K.H., Godfrey, K.M., Gluckman, P.D., Shek, L.P.C., Yap, F., Kramer, M.S., Chan, S.Y., Chong, Y.S.“…STUDY FUNDING/COMPETING INTEREST(S): This research was supported by the Singapore National Research Foundation under its Translational and Clinical Research (TCR) Flagship Program and administered by the Singapore Ministry of Health's National Medical Research Council (NMRC), Singapore (NMRC/TCR/004-NUS/2008; NMRC/TCR/012-NUHS/2014). …”
Publicado 2017
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147086por Cox, Sharon E, Ellins, Elizabeth A, Marealle, Alphonce I, Newton, Charles R, Soka, Deogratias, Sasi, Philip, Luca Di Tanna, Gian, Johnson, William, Makani, Julie, Prentice, Andrew M, Halcox, Julian P, Kirkham, Fenella J“…Long-term studies are required to assess whether these physiological effects translate to improved clinical outcomes and better growth and development in patients with sickle-cell disease. …”
Publicado 2018
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147087por Del-Ben, Cristina, Rosana, Shuhama, Loureiro, Camila, Ragazzi, Taciana, Zanatta, Daniela, Tenan, Silvia, Ferreira-Santos, Jair, Louzada-Junior, Paulo, dos Santos, Antonio, Morgan, Craig, Menezes, Paulo“…BACKGROUND: In the study “Schizophrenia and Other Psychoses Translational Research: Environment and Molecular Biology” (STREAM), we estimated the incidence of first-episode psychosis (FEP) in the catchment area of Ribeirão Preto, Brazil, and investigated the role of environmental and biological factors in the aetiology of the psychoses. …”
Publicado 2018
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147088“…In 2015, the instructors included the PMI as the recurrent case study introduced at the beginning and referred to throughout the course, and as a class exercise allowing students to translate issues into policy. In 2016, an entire class session was devoted to precision medicine and precision public health. …”
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147089por Li, Yan-Feng, Zhu, Tong, Zhang, Yong, Luo, Yong, Li, Ke, Liu, Xu-Dong, Zhou, Bo, Li, Zhong-Tai, Jiang, JunEnlace del recurso
Publicado 2018
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147090por Hapangama, D K, Drury, J, Da Silva, L, Al-Lamee, H, Earp, A, Valentijn, A J, Edirisinghe, D P, Murray, P A, Fazleabas, A T, Gargett, C E“…We also acknowledge the support of Liverpool Women’s Hospital Foundation Trust (J.D.), Institute of Translational Medicine (L.D.S., H.A.L., A.J.V., D.K.H.), University of Liverpool, the National Health and Medical Research Council of Australia ID 1042298 (C.E.G.) and the Victorian Government Operational Infrastructure Support Fund. …”
Publicado 2019
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147091“…Our use of the clinically approved materials, along with confirmation by theoretical simulations, make this technique a promising candidate for translational MR cancer theranostics.…”
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147092por Iwamoto, Sean, Halliday, Tanya, Hild, Allison, Rakeen, Bahroze, Tregellas, Jason, Cornier, Marc-Andre“…Research Support: NIH Grant T32, ADA Translational Science Award, VA Eastern Colorado Health Care System GRECC Pilot Project and Fellowship…”
Publicado 2019
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147093por Gehrig, Jeanette L., Venkatesh, Siddarth, Chang, Hao-Wei, Hibberd, Matthew C., Kung, Vanderlene L., Cheng, Jiye, Chen, Robert Y., Subramanian, Sathish, Cowardin, Carrie A., Meier, Martin F., O’Donnell, David, Talcott, Michael, Spears, Larry D., Semenkovich, Clay F., Henrissat, Bernard, Giannone, Richard J., Hettich, Robert L., Ilkayeva, Olga, Muehlbauer, Michael, Newgard, Christopher B., Sawyer, Christopher, Head, Richard D., Rodionov, Dmitry A., Arzamasov, Aleksandr A., Leyn, Semen A., Osterman, Andrei L., Hossain, Md Iqbal, Islam, Munirul, Choudhury, Nuzhat, Sarker, Shafiqul Alam, Huq, Sayeeda, Mahmud, Imteaz, Mostafa, Ishita, Mahfuz, Mustafa, Barratt, Michael J., Ahmed, Tahmeed, Gordon, Jeffrey I.“…CONCLUSION: These findings demonstrate the translatability of results obtained from pre-clinical gnotobiotic animal models to humans, directly support the hypothesis that healthy microbiota development is causally linked to healthy growth, illustrate an approach for treating childhood undernutrition, and with the capacity to deliberately reconfigure immature microbiota, suggest a means to decipher how elements of the gut microbial community operate to regulate various host systems involved in healthy growth.…”
Publicado 2019
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147094por Pike, Mindy, Robinson-Cohen, Cassianne, Morse, Jennifer, Stewart, Thomas G., Blot, William J., Alp Ikizler, T., Lipworth, LorenEnlace del recurso
Publicado 2019
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147095
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147096por Bennett-Irby, Megan, Summers, Phillip, Moore, Keena R., Daniel, Stephanie, Skelton, Jospeh A., Rhodes, Scott D.Enlace del recurso
Publicado 2019
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147097
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147098por Wang, Bing Mei, Parrott, Jocelyn, Brunger, Jennifer, Beggs, Pauline, Chapman, JocelynEnlace del recurso
Publicado 2019
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147099
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147100por Chang, Andrew Y., Askari, Mariam, Fan, Jun, Heidenreich, Paul A., Ho, P. Michael, Mahaffey, Kenneth W., Perino, Alexander C., Turakhia, Mintu P.Enlace del recurso
Publicado 2018
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