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147101
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147102
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147103
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147104
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147105por Howard-Anderson, Jessica, Blakney, Rebekah, Bower, Christopher, Sexton, Mary Elizabeth, Satola, Sarah W., Farley, Monica M., Jacob, Jesse T.Enlace del recurso
Publicado 2019
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147106“…PCL-5 scores were dichotomized using the 33rd and 66th percentiles, translating into low (≤ 24), moderate (25–47), and severe (≥48) groups. …”
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147107
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147108“…These enzymes play a key role in protein translation by the addition of amino acids to their cognate tRNA. …”
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147109por Mansi, Rosalba, Abid, Karim, Nicolas, Guillaume P., Del Pozzo, Luigi, Grouzmann, Eric, Fani, Melpomeni“…It compares favorably with the clinically used [(68)Ga]Ga-DOTA-NOC in terms of tumor uptake; however, its uptake in the liver remains a challenge for clinical translation. In addition, this study reveals the essential role of the iodo-substitutions in positions 1 and 3 of [(68)Ga]Ga-DOTA-ST8950 for maintaining affinity to SST2 and SST5, as the de-iodinated [(68)Ga]Ga-DOTA-ST8951 lost affinity for both receptor subtypes.…”
Publicado 2020
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147111por Schmalz, Oliver, Jacob, Christine, Ammann, Johannes, Liss, Blasius, Iivanainen, Sanna, Kammermann, Manuel, Koivunen, Jussi, Klein, Alexander, Popescu, Razvan Andrei“…Survey data were analyzed quantitatively; interviews were recorded, transcribed verbatim, and translated into English, where applicable, for coding and qualitative thematic analysis. …”
Publicado 2020
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147112por Nayak, Rusheel, Barrett, Joshua, Patel, Milap S., Barbosa, Mauricio P., Kadakia, Anish R.“…This study determines how these guidelines translate to operative outcomes, measured using Patient-Reported Outcomes Measurement Information System (PROMIS) Physical Function (PF) and Pain Interference (PI) surveys. …”
Publicado 2021
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147113por Lamarca, Angela, Palmer, Daniel H, Wasan, Harpreet Singh, Ross, Paul J, Ma, Yuk Ting, Arora, Arvind, Falk, Stephen, Gillmore, Roopinder, Wadsley, Jonathan, Patel, Kinnari, Anthoney, Alan, Maraveyas, Anthony, Iveson, Tim, Waters, Justin S, Hobbs, Claire, Barber, Safia, Ryder, W David, Ramage, John, Davies, Linda M, Bridgewater, John A, Valle, Juan W“…FUNDING: Cancer Research UK, StandUpToCancer, AMMF (The UK Cholangiocarcinoma Charity), and The Christie Charity, with additional funding from The Cholangiocarcinoma Foundation and the Conquer Cancer Foundation Young Investigator Award for translational research.…”
Publicado 2021
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147114por de Freitas, Maria Cristina Foss, Akinci, Baris, Corsa, Callie, Rothberg, Amy E, MacDougald, Ormond A, Oral, Elif A“…Animal studies from our group have identified an association between adipose tissue loss and an increase in bone mineral density (BMD) in a mouse model with adipose tissue specific knockout of LMNA gene. Aiming to translate this observation to patients with FPLD2, we analyzed body composition data obtained by dual X-ray absorptiometry from 61 patients diagnosed with FPLD2 and 61 individuals with no diagnosis of FPLD (nFPLD) matched for sex, age and body mass index. …”
Publicado 2021
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147115por Haraka, Frederick, Kakolwa, Mwaka, Schumacher, Samuel G, Nathavitharana, Ruvandhi R, Denkinger, Claudia M, Gagneux, Sebastien, Reither, Klaus, Ross, Amanda“…However, it is not clear whether the greater accuracy of the test translates into improved health outcomes. OBJECTIVES: To assess the impact of Xpert MTB/RIF on patient outcomes in people being investigated for tuberculosis. …”
Publicado 2021
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147116por Wang, Wenlun, Min, Lu, Qiu, Xinyuan, Wu, Xiaomin, Liu, Chuanyang, Ma, Jiaxin, Zhang, Dongyi, Zhu, Lingyun“…Long non-coding RNAs (lncRNAs) regulate gene expression in a variety of ways at epigenetic, chromatin remodeling, transcriptional, and translational levels. Accumulating evidence suggests that lncRNA X-inactive specific transcript (lncRNA Xist) serves as an important regulator of cell growth and development. …”
Publicado 2021
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147117por Kohlmorgen, Christina, Gerfer, Stephen, Feldmann, Kathrin, Twarock, Sören, Hartwig, Sonja, Lehr, Stefan, Klier, Meike, Krüger, Irena, Helten, Carolin, Keul, Petra, Kahl, Sabine, Polzin, Amin, Elvers, Margitta, Flögel, Ulrich, Kelm, Malte, Levkau, Bodo, Roden, Michael, Fischer, Jens W., Grandoch, Maria“…METHODS: Male, 8-week-old LDL-receptor-deficient (Ldlr(−/−)) mice received a high-fat, high-sucrose diabetogenic diet supplemented without (control) or with dapagliflozin (5 mg/kg body weight per day) for two time periods: 8 and 25 weeks. In a first translational approach, eight healthy volunteers received 10 mg dapagliflozin/day for 4 weeks. …”
Publicado 2021
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147118por Crump, R. Trafford, Remmers, Sebastiaan, Van Hemelrijck, Mieke, Helleman, Jozien, Nieboer, Daan, Roobol, Monique J., Venderbos, Lionne D. F., Trock, Bruce, Ehdaie, Behfar, Carroll, Peter, Filson, Christopher, Logothetis, Christopher, Morgan, Todd, Klotz, Laurence, Pickles, Tom, Hyndman, Eric, Moore, Caroline, Gnanapragasam, Vincent, Van Hemelrijck, Mieke, Dasgupta, Prokar, Bangma, Chris, Roobol, Monique, Villers, Arnauld, Robert, Grégoire, Semjonow, Axel, Rannikko, Antti, Valdagni, Riccardo, Perry, Antoinette, Hugosson, Jonas, Rubio-Briones, Jose, Bjartell, Anders, Hefermehl, Lukas, Shiong, Lee Lui, Frydenberg, Mark, Sugimoto, Mikio, Chung, Byung Ha, van der Kwast, Theo, Hulsen, Tim, de Jonge, Cees, van Hooft, Peter, Kattan, Mike, Xinge, Ji, Muir, Kenneth, Lophatananon, Artitaya, Fahey, Michael, Steyerberg, Ewout, Nieboer, Daan, Zhang, Liying, Steyerberg, Ewout, Nieboer, Daan, Beckmann, Kerri, Denton, Brian, Hayen, Andrew, Boutros, Paul, Guo, Wei, Benfante, Nicole, Cowan, Janet, Patil, Dattatraya, Park, Lauren, Ferrante, Stephanie, Mamedov, Alexandre, LaPointe, Vincent, Crump, Trafford, Stavrinides, Vasilis, Kimberly-Duffell, Jenna, Santaolalla, Aida, Nieboer, Daan, Olivier, Jonathan, France, Bordeaux, Rancati, Tiziana, Ahlgren, Helén, Mascarós, Juanma, Löfgren, Annica, Lehmann, Kurt, Lin, Catherine Han, Cusick, Thomas, Hirama, Hiromi, Lee, Kwang Suk, Jenster, Guido, Auvinen, Anssi, Bjartell, Anders, Haider, Masoom, van Bochove, Kees, Buzza, Mark, Kouspou, Michelle, Paich, Kellie, Bangma, Chris, Roobol, Monique, Helleman, JozienEnlace del recurso
Publicado 2021
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147119por Hiremath, Amogh, Shiradkar, Rakesh, Fu, Pingfu, Mahran, Amr, Rastinehad, Ardeshir R, Tewari, Ashutosh, Tirumani, Sree Harsha, Purysko, Andrei, Ponsky, Lee, Madabhushi, Anant“…FUNDING: National Cancer Institute of the US National Institutes of Health, National Institute for Biomedical Imaging and Bioengineering, National Center for Research Resources, US Department of Veterans Affairs Biomedical Laboratory Research and Development Service, US Department of Defense, US National Institute of Diabetes and Digestive and Kidney Diseases, The Ohio Third Frontier Technology Validation Fund, Case Western Reserve University, Dana Foundation, and Clinical and Translational Science Collaborative.…”
Publicado 2021
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147120por Dong, Xue, Premaratne, Ishani, Gadjiko, Mariam, Berri, Nabih, Limem, Skander, Sariibrahimoglu, Kemal, Scott, Jeffrey, Spector, Jason“…Because P4HB devices for soft tissue reinforcement have previously been cleared by the FDA and possess a long track record of safety, we believe that this novel 3D-P4HB nipple reconstruction scaffold may be readily translatable to the clinic.…”
Publicado 2021
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