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1581“…This is of high significance because instead of increasing the GDP spent in public health, we should focus on the increasing the translational research spending, as this would lead to improved solutions. …”
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1582“…In this review, we discuss how ribosome profiling applied to mycobacteria has led to discoveries about translational regulation. Using case studies, we show that the traditional view of “canonical” translation mechanisms needs expanding to encompass features of mycobacterial translation that are more widespread than previously recognized. …”
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1583“…As EV cargo has major influence on their functionality, understanding and translating the biology underlying the packaging and transferring of biomolecule cargos (e.g. miRNAs, pathogen antigens, small molecule drugs) into EVs is key in harnessing their therapeutic potential. …”
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1584
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1585por Jiang, Peng, Sinha, Sanju, Aldape, Kenneth, Hannenhalli, Sridhar, Sahinalp, Cenk, Ruppin, Eytan“…Indeed, the combination of big data, bioinformatics and artificial intelligence has led to notable advances in our basic understanding of cancer biology and to translational advancements. Further advances will require a concerted effort among data scientists, clinicians, biologists and policymakers. …”
Publicado 2022
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1586“…While the quantification of comparative trade-offs is critical for accurate process-level decision making, the translation of industrial ecology to synthetic biology is often ambiguous and assessment accuracy has proven challenging. …”
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1587
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1588
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1589
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1590
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1591por Grech, Olivia, Sassani, Matilde, Terwindt, Gisela, Lavery, Gareth G., Mollan, Susan P., Sinclair, Alexandra J.“…Understanding the translational relevance of these studies are important to identifying triggers, biomarkers and therapeutic targets in migraine. …”
Publicado 2022
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1592por Munthe, Christian“…While suggested ethics frameworks for translational medicine build on clearly distinguishing these models, actual TGM typically blurs them. …”
Publicado 2021
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1593
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1594“…Protein translation is a foundational attribute of all living cells. …”
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1595por Kumar, Sangeetha Devi, Kar, Debaleena, Akhtar, Md Noor, Willard, Belinda, Roy, Debadrita, Hussain, Tanweer, Rajyaguru, Purusharth I., Eswarappa, Sandeep M“…However, the absence of translation is not consistent with the long lifespan of mature erythrocytes. …”
Publicado 2022
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1596por Hoyez, Henri, Schockaert, Cédric, Rambach, Jason, Mirbach, Bruno, Stricker, Didier“…Supervised image-to-image translation has been proven to generate realistic images with sharp details and to have good quantitative performance. …”
Publicado 2022
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1597
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1598“…In addition, PTEN can also be regulated by post-translational modifications. Acetylation, oxidation, phosphorylation, sumoylation, and ubiquitination can alter PTEN stability, cellular localization, or activity, highlighting the complexity of PTEN regulation. …”
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1599por Huang, Erich P., O’Connor, James P. B., McShane, Lisa M., Giger, Maryellen L., Lambin, Philippe, Kinahan, Paul E., Siegel, Eliot L., Shankar, Lalitha K.“…However, despite the thousands of radiomic studies, the number of settings in which radiomics has been successfully translated into a clinically useful tool or has obtained FDA clearance is comparatively small. …”
Publicado 2022
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1600“…Translation always faces various ethics issues. Ethics in translation has attracted widespread attention from researchers around the world. …”
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