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1641por Chicherin, Ivan, Levitskii, Sergey, Baleva, Maria V., Krasheninnikov, Igor A., Patrushev, Maxim V., Kamenski, Piotr“…Thus, mitochondrial translation is of great importance for the organelle as well as for the whole cell. …”
Publicado 2020
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1642por Annapragada, Ananth, Sikora, Andrew, Bollard, Catherine, Conejo-Garcia, Jose, Cruz, Conrad Russell, Demehri, Shadmehr, Demetriou, Michael, Demirdjian, Levon, Fong, Lawrence, Horowitz, Mary, Hutson, Alan, Kadash-Edmondson, Kathryn, Kufe, Donald, Lipkin, Steven, Liu, Song, McCarthy, Claire, Morgan, Martin, Morris, Zachary, Pan, Yang, Pasquini, Marcelo, Schoenberger, Stephen, Van Allen, Eliezer, Vilar, Eduardo, Xing, Yi, Zha, Wenjuan, Odunsi, Adekunle“…As part of the Cancer Moonshot initiative, the Immuno-Oncology Translational Network (IOTN) was established to accelerate the translation of basic discoveries to improve immunotherapy outcomes across the spectrum of adult cancers and to develop immune-based approaches that prevent cancers before they occur. …”
Publicado 2020
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1645“…Yet the field lacks methodological approaches to rigorously translate those strategies into evidence-based interventions to improve collaborative translational research. …”
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1646“…As the USA and the rest of the world raced to fight the COVID-19 pandemic, years of investments from the National Center for Advancing Translational Sciences allowed for informatics services and resources at CTSA hubs to play a significant role in addressing the crisis. …”
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1647por Mouraux, André, Bannister, Kirsty, Becker, Susanne, Finn, David P., Pickering, Gisèle, Pogatzki‐Zahn, Esther, Graven‐Nielsen, Thomas“…For decades, basic research on the underlying mechanisms of nociception has held promise to translate into efficacious treatments for patients with pain. …”
Publicado 2021
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1648“…Despite the long tradition of previous Chinese Presidents using ACPP in their political addresses, the translation work on the three volumes of Xi Jinping: The Governance of China with much ACPP still poses a daunting challenge to the translation of literary texts in non-literary texts. …”
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1649por Volkov, Boris B., Ragon, Bart, Holmes, Kristi, Samuels, Elias, Walden, Anita, Herzog, Keith“…COVID-19 reinforced the need for effective leadership and administration within Clinical and Translational Science Award (CTSA) program hubs in response to a public health crisis. …”
Publicado 2022
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1650“…Translational science is, by definition, groundbreaking; however, without an emphasis on quality and efficiency, some innovations in healthcare may translate into unnecessary risk, suboptimal solutions, and potentially loss of well-being and even lives. …”
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1651por Mann, Douglas L.Materias: “…Translational Perspective…”
Publicado 2023
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1652por Lapaige, Véronique“…Secondly, even if one wanted to apply a “transfrontier knowledge translation” vision, how should one go about doing so? …”
Publicado 2010
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1653“…BACKGROUND: Within the scanning model of translation initiation, reinitiation is a non-canonical mechanism that operates on mRNAs harboring upstream open reading frames. …”
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1654por Overcash, Ryan F., Chappell, Vesna A., Green, Thomas, Geyer, Christopher B., Asch, Adam S., Ruiz-Echevarría, Maria J.“…Using chemical and siRNA inhibition of the androgen receptor (AR), we show that the androgen effect on TMEFF2 translation is mediated by the AR. Importantly, DHT also promotes phosphorylation of the α subunit of the translation initiation factor 2 (eIF2α) in an AR-dependent manner, paralleling the effect on TMEFF2 translation. …”
Publicado 2013
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1655por Spoth, Richard, Rohrbach, Louise A., Greenberg, Mark, Leaf, Philip, Brown, C. Hendricks, Fagan, Abigail, Catalano, Richard F., Pentz, Mary Ann, Sloboda, Zili, Hawkins, J. David“…We also summarize a heuristic “Translation Science to Population Impact (TSci Impact) Framework.” …”
Publicado 2013
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1656“…It becomes even more challenging when local languages do not have equivalent scientific and technical vocabularies, rendering communication of scientific concepts in translated documents extremely difficult. Even when bilingual lexicons are developed, there is no guarantee that participants understand the terminology as translated. …”
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1657“…Long noncoding RNAs (lncRNAs) are important regulators of transcription; however, their involvement in protein translation is not well known. Here we explored whether the lncRNA GAS5 is associated with translation initiation machinery and regulates translation. …”
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1658por Chen, HH, Phillips, MR, Cheng, H, Chen, QQ, Chen, XD, Fralick, D, Zhang, YE, Liu, M, Huang, J, Bueber, M“…The following document is a translation of the first national mental health law of the People's Republic of China, which was adopted by the National People's Congress on October 26, 2012. …”
Publicado 2012
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1659por Ahyong, Vida, Sheridan, Christine M., Leon, Kristoffer E., Witchley, Jessica N., Diep, Jonathan, DeRisi, Joseph L.“…Dose–response curves were determined in both translation systems to further characterize the top hit compound (MMV008270). …”
Publicado 2016
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1660por Carraro, Ugo“…All these events will be sponsored by the Interdepartmental Research Centre of Myology of the University of Padova and by the A&CM Carraro Foundation for Translational Myology.…”
Publicado 2017
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