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  1. 1861
  2. 1862
    por Lahan, Vivekananda, Gupta, Ravi
    Publicado 2011
    “…Translation was carried out by using standard translation procedures, such as combined translation, decentering, and pretest method. …”
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  3. 1863
  4. 1864
    “…Genes encoding ribosomal protein are preferentially regulated at the translational level, which possibly contributes to the enhanced translation efficiency. …”
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  5. 1865
  6. 1866
    “…NRs are regulated by post-translational modifications (PTM) that markedly impact receptor function. …”
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  7. 1867
    por Castro-Roa, Daniel, Zenkin, Nikolay
    Publicado 2012
    “…Transcription and translation are coupled in bacteria, meaning that translation takes place co-transcriptionally. …”
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  8. 1868
    “…It is widely believed that synonymous codons are translated with unequal speeds and that translational efficiency is maximized by the exclusive use of rapidly translated codons. …”
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  9. 1869
    “…Here, we demonstrate that these devices can translate DNA genes encoding 384 diversity elements per coding position into corresponding small-molecule gene products. …”
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  10. 1870
    “…Therefore, the ratio of TAp73 isoforms to ΔNp73 isoforms is critical for the quality of the response to a genomic insult and needs to be delicately regulated at both transcriptional and post-translational level. In this review, we will summarize the current knowledge on the post-translational regulatory pathways involved to keep p73 protein under control. …”
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  11. 1871
    “…In 2003, the Journal of Translational Medicine was launched to foster the publication of high quality research in both "bench-to-bedside" as well as ex vivo human observation. …”
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  12. 1872
    “…The composition of the cellular proteome is under the control of multiple processes, one of the most important being translation initiation. The majority of eukaryotic cellular mRNAs initiates translation by the cap-dependent or scanning mode of translation initiation, a mechanism that depends on the recognition of the m(7)G(5′)ppp(5′)N, known as the cap. …”
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  13. 1873
    por Wendler, Alexandra, Wehling, Martin
    Publicado 2012
    “…Translational medicine describes the transfer of basic in vitro and in vivo data into human applications. …”
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  14. 1874
    “…Interestingly, the novel super-families are translation inhibitors similar to the majority of known toxins indicating that this activity might have been selected rather than more detrimental traits such as DNA-gyrase inhibitors, which are very toxic for cells.…”
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  15. 1875
    “…Translationally controlled tumor protein (TCTP) is a highly conserved and ubiquitously expressed protein in all eukaryotes—highlighting its important functions in the cell. …”
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  16. 1876
  17. 1877
  18. 1878
  19. 1879
    “…One-hour of unanticipated darkness reduced levels of polysomes by 17% in a manner consistent with inhibition of initiation of translation. This down-regulation of translation was reversed within 10 min of re-illumination. …”
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  20. 1880
    “…These criteria enabled identification of the mRNA being translated by a given ribosome to within 95% confidence intervals based on the number of identified FRET traces. …”
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