“…BAX is a critical apoptotic regulator that can be transformed from a cytosolic monomer into a lethal mitochondrial oligomer, yet drug strategies to modulate it are underdeveloped due to longstanding difficulties in conducting screens on this aggregation-prone protein. …”
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“…Nevertheless, our results provide information on the high prevalence of health problems being experienced by children living in one of the most isolated and underdeveloped volcano mountain areas in Indonesia and draws attention to the severe effects of malnutrition on the development of those children.…”
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“…However, the realization of their full potential has been hindered by both their underdeveloped synthesis and the poor understanding of their optoelectronic properties, whose origins are still under intense debate. …”
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“…The incidence of this disorder in underdeveloped countries is much more than developed areas. …”
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“…However, the potential of carbon nanotubes (CNTs) as nanofiller in reinforced epoxy composites like glass fiber-reinforced polymers (GFRP) or carbon fiber-reinforced polymers (CFRP) under dynamic testing is still underdeveloped. The goal of this study is to investigate the effect of integrating nanofillers such as CNTs into the epoxy matrix of carbon fiber reinforced polymer composites (CFRP) on their dynamic energy absorption potential under impact. …”
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“…Advances have been made in the forensic analysis of microbes and toxins. An underdeveloped and underutilized area in microbial forensics is how the host interacts with microorganisms in a way that provides unique signatures for forensic use. …”
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“…Related chemistry with boron and silicon nucleophiles where the boryl- and accordingly silylcopper intermediates are catalytically regenerated from bench-stable pronucleophiles had been underdeveloped for years or did not even exist until recently. …”
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“…Synchronized flowering in certain environments is a prerequisite to commercial seed production, and so the elucidation of the genetic architecture of flowering time in Miscanthus and switchgrass could aid breeding in these underdeveloped species. In this context, we assessed a mapping population in Miscanthus and two ecologically diverse switchgrass mapping populations over 3 years from planting. …”
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“…The findings show the relevance of solidarity with certain stakeholders during the pandemic, but also reveal the fragility of PFCs due to their financial structure and underdeveloped managerial and entrepreneurial strategies to cope with the crisis. …”
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“…CONCLUSION: Prevention and control policies for older adults and underdeveloped areas and sex differences need to be studied.…”
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“…This paper considers how the three sets of bilateral relations, between the European Union (EU) and Japan, the EU and Turkey, and Turkey and Japan, have developed (or been underdeveloped) and how the three have failed to form a strategic triangle that could potentially be beneficial for dealing with regional and international problems more efficiently. …”
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“…Specifically, in Latin America, pediatric palliative care services have emerged unevenly and are still considered underdeveloped when compared to other regions of the world. …”
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“…Supportive care facilities are underdeveloped in most low resource settings including in India. …”
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“…Whereas their preparation has historically relied on ligand synthesis followed by coordination to metal centers, the ability to efficiently diversify their structures remains a synthetic challenge. A promising yet underdeveloped strategy involves the direct manipulation of ligands that are already bound to a metal center, also known as chemistry-on-the-complex. …”
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“…Introduction Limited data is available on which interventions are likely to improve compliance to hand hygiene, especially in underdeveloped countries. The objective of this study is to explore whether the introduction of a particular bundle of strategies to improve hand hygiene is effective. …”
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“…Occasionally, they are used for purely recreational purposes, this being their main use in the modern societies of both industrialized and underdeveloped nations. However, it must be noted that the hallucinogenic or psychedelic experiences, recreational, are not always euphoric. …”
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“…Acute subdural hemorrhage may be caused by an insignificant blow to the coronal suture in infantile patients with underdeveloped cranial bones and sutures, accompanied by subtle external findings.…”
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“…Model simulations are essential for quantitative understanding of these features and their origins, however systematic comparisons with real data are underdeveloped. Here, by employing deep-learning-based feature extraction combined with phase-field modeling framework, we show that a low dimensional feature space for 2D migrating cell morphologies obtained from the shape stereotype of keratocytes, Dictyostelium and neutrophils can be fully mapped by an interlinked signaling network of cell-polarization and protrusion dynamics. …”
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“…The poor situational awareness about the spreading of the virus especially in the underdeveloped regions calls for novel virus assays of low cost and simple operation. …”
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“…The control of site selectivity in asymmetric mono‐hydrogenation of dienes or polyenes remains largely underdeveloped. Herein, we present a highly efficient desymmetrization of 1,4‐dienes via iridium‐catalyzed site‐ and enantioselective hydrogenation. …”
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