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1501Structural basis of subtype-selective competitive antagonism for GluN2C/2D-containing NMDA receptorspor Wang, Jue Xiang, Irvine, Mark W., Burnell, Erica S., Sapkota, Kiran, Thatcher, Robert J., Li, Minjun, Simorowski, Noriko, Volianskis, Arturas, Collingridge, Graham L., Monaghan, Daniel T., Jane, David E., Furukawa, Hiro“…While specific compounds for GluN2A and GluN2B-containing NMDARs are well established, those that target GluN2C and GluN2D are currently underdeveloped with low potency and uncharacterized binding modes. …”
Publicado 2020
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1502por Stone, Kayla D., Kornblad, Clara A. E., Engel, Manja M., Dijkerman, H. Chris, Blom, Rianne M., Keizer, Anouk“…Perhaps sensory input, processed normally on and about the limb, cannot communicate with a higher-order model of the leg in the brain (which might be underdeveloped). We asked individuals who desire paralysis or amputation of the lower legs (and a group of age- and sex-matched controls) to make explicit and implicit judgments about the size and shape of their legs while relying on vision, touch, and proprioception. …”
Publicado 2020
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1503por Wang, Zhuo, Luo, Yu, Yang, Shujuan, Zuo, Mingliang, Pei, Rong, He, Jun, Deng, Yin, Zhou, Maigeng, Zhao, Li, Guo, Hui, Zou, Kun“…Sichuan province is the largest and underdeveloped region in southwest China, with 486 thousand square kilometers, more than 80 million residents, unbalanced economic development, and high prevalence, low awareness, low treatment and low control rate of hypertension. …”
Publicado 2020
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1504“…CONCLUSION: This review identified several features associated with the design and implementation of intelligent online triage tools in a primary care context, although most of the investigated systems seemed underdeveloped and offered limited benefits. Current online triage systems should not be used by individuals who have reasonable access to traditional healthcare. …”
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1505“…However, several healthcare facilities in underdeveloped countries cannot afford this instrument; hence, they usually perform subjective visual assessment to check the patient’s identity. …”
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1506por Karuppan, Mohan Kumar Muthu, Ojha, Chet Raj, Rodriguez, Myosotys, Lapierre, Jessica, Aman, M. Javad, Kashanchi, Fatah, Toborek, Michal, Nair, Madhavan, El-Hage, Nazira“…Despite a low mortality rate among the infected dams, 25% of Becn1(+/−) offspring were smaller in size and had smaller, underdeveloped brains. This phenotype became apparent after 2-to 3-weeks post-birth. …”
Publicado 2020
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1507por Easterlin, Molly C., De Beritto, Theodore, Yeh, Amy M., Wertheimer, Fiona B., Ramanathan, Rangasamy“…The literature is especially lacking on the effects of SARS-CoV-2 on extremely preterm (<28 weeks gestation) infants who have underdeveloped immune systems. We report the case of an extremely preterm, 25-week 5-days old infant, born to a mother with severe COVID-19 (coronavirus disease-2019) pneumonia. …”
Publicado 2020
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1508“…Generally the number of deaths per million population are higher in the developed countries despite better health care efficiency, drinking water quality and expected healthy life span (HALE) at the time of birth. Developing and underdeveloped countries on the other hand have lower mortality even with higher rural and slum populations along with incidence of diarrhea because of lack of sanitation. …”
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1509por Kakakhel, M.A., Wu, F., Khan, T.A., Feng, H., Hassan, Z., Anwar, Z., Faisal, S., Ali, I., Wang, W.“…As an underdeveloped country, the coronavirus disease 2019 (COVID-19) epidemic has posed a major risk to the health and economy of Pakistan. …”
Publicado 2020
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1510por Culen, Caroline, Herle, Marion, Ertl, Diana‐Alexandra, Fröhlich‐Reiterer, Elke, Blümel, Peter, Wagner, Gudrun, Häusler, Gabriele“…By incorporating the assessment of transition readiness specialists will find it easier to identify underdeveloped skills and knowledge gaps in their patients. …”
Publicado 2020
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1511por Liu, Linsheng, Jin, Xurui, Wu, Yangfeng, Yang, Mei, Xu, Tao, Li, Xianglian, Ren, Jianhong, Yan, Lijing L.“…Conventional diagnostic methods are dependent on advanced instruments, which are expensive, inaccessible, and inconvenient in underdeveloped areas. To build a novel dried blood spot (DBS) detection strategy for imaging CVDs, in this study, a total of 12 compounds, including seven amino acids [homocysteine (Hcy), isoleucine (Ile), leucine (Leu), valine (Val), phenylalanine (Phe), tyrosine (Tyr), and tryptophan (Trp)], three amino acid derivatives [choline, betaine, and trimethylamine N-oxide (TMAO)], L-carnitine, and creatinine, were screened for their ability to identify CVD. …”
Publicado 2020
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1512por Busatto, Serena, Ruiter, Mariska de, Jastrzebski, Johann T. B. H., Albrecht, Wiebke, Pinchetti, Valerio, Brovelli, Sergio, Bals, Sara, Moret, Marc-Etienne, de Mello Donega, Celso“…[Image: see text] Despite recent advances, the synthesis of colloidal InSb quantum dots (QDs) remains underdeveloped, mostly due to the lack of suitable precursors. …”
Publicado 2020
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1513“…Overall, our findings highlight the need for more research in underdeveloped countries, to investigate the potential of overlooked carabids and include response variables measuring functional diversity in assessing the sustainability of agricultural management. …”
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1514“…INTRODUCTION: viral hepatitis B remains a major public health problem around the world, especially in underdeveloped and developing countries. Cameroon shows a grate variability in prevalence of this infection in the country and even within different populations groups. …”
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1515“…Communities are seeking ways to enhance cross-sector collaboration and overcome underdeveloped relationships and fragmentation that are barriers to effective public health responses. …”
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1516“…Findings reveal an underdeveloped area of social work practice, and highlight opportunities for researchers and practitioners to define gerontological social workers’ role in emergency management and detail best practice guidelines.…”
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1517por Takoudjou Dzomo, Guy Rodrigue, Bernales, Margarita, López, Rodrigo, Djofang Kamga, Yves, Kila Roskem, Jean Pierre, Deassal Mondjimbaye, Francis, Nanbolngar, Joseph, Modode, Richard, Rongar, Roger, Diba, Faro, Toglengar, Madjadoum, Ongolo, Jean Pierre, Gómez-Vírseda, Carlos“…Among them, Chad is characterized by a high rate of poverty and mortality, a high burden of infectious diseases, insufficient epidemiological surveillance and underdeveloped infrastructure. In this study, we explore the knowledge, attitudes and practices (KAPs) regarding COVID-19 within the Chadian population, to determine whether there are more vulnerable groups of the population that require greater attention from authorities. …”
Publicado 2021
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1518“…Taken together, these findings suggest that cognitive empathy, as quantified by the RMET, centrally involves imagination, which is underdeveloped (with a male bias) on the autism spectrum and overdeveloped (with a female bias) on the schizotypy spectrum, with optimal emotion-recognition performance intermediate between the two. …”
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1519“…Finally, policymakers and concerned non-governmental institutions should fully understand the sensitivity of the rural population in underdeveloped mountain areas to climate factors to promote their rational distribution.…”
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1520“…Based on our results, we propose that FRD could be a candidate for cervical screening, especially in underdeveloped countries.…”
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