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  1. 1001
    “…All isolates were positive for both genes vacA s1 and vacA s1a. CONCLUSION : These results suggested that many of the H. pylori-infected Korean patients were actually colonized with mixed populations of different H. pylori strains and that the prevalence of duodenal H. pylori expression of the cagA and/or vacA gene was not correlated with the development of duodenal ulcer in Korean patients.…”
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    High Prevalence of Multiple Strain Colonization of Helicobacter pylori in Korean Patients: DNA Diversity Among Clinical Isolates from the Gastric Corpus, Antrum and Duodenum
  2. 1002
    “…The vacA s1 frequency was significantly higher than that of vacA m1/cagA+/babA2+ in chronic superficial gastritis (p = 0.000), peptic ulcer (p = 0.037) and gastric erosion (p = 0.009). …”
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    An improved quantitative real-time polymerase chain reaction technology for Helicobacter pylori detection in stomach tissue and its application value in clinical precision testing
  3. 1003
    “…Genotyping for cagA, cagA3(/) subtypes, babA2 and vacA was performed by PCR using sequence specific primers. …”
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    Virulence attributes of Helicobacter pylori isolates & their association with gastroduodenal disease
  4. 1004
    “…Analysis of virulence factors revealed that 43.9% of the strains were cagA-positive, and the vacA s1 allele was detected in 56.0% of the isolates. …”
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    Rapid Characterization of Virulence Determinants in Helicobacter pylori Isolated from Non-Atrophic Gastritis Patients by Next-Generation Sequencing
  5. 1005
    “…IL-17 and IL-23 mRNA expression in mucosa of patients with vacA m1 were significantly higher than those observed in patients with vacA m2. …”
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    Association of the virulence factors of Helicobacter pylori and gastric mucosal interleukin-17/23 mRNA expression in dyspeptic patients
  6. 1006
    “…Persistent infection with Helicobacter pylori (H. pylori) is an important factor in gastric diseases. The vacA and cagA virulence factors of H. pylori contribute to the development of these diseases. …”
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    Helicobacter pylori Virulence Factors and Clarithromycin Resistance-Associated Mutations in Mexican Patients
  7. 1007
    “…Gastric cancer cells were infected with H. pylori wild type (vacA+/cagA+), single mutant (ΔvacA or ΔcagA) or double mutant (ΔvacA/ΔcagA) strains and plasma membrane disruption events and consequent activation of membrane repair components monitored. …”
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    Helicobacter pylori Disrupts Host Cell Membranes, Initiating a Repair Response and Cell Proliferation
  8. 1008
    “…Previously, we found that risk of colorectal cancer (CRC) is increased in individuals with serum antibody response to both Helicobacter pylori (HP) Vacuolating Cytotoxin (VacA) toxin or Streptococcus gallolyticus (SGG) pilus protein Gallo2178. …”
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    Association of Combined Sero-Positivity to Helicobacter pylori and Streptococcus gallolyticus with Risk of Colorectal Cancer
  9. 1009
    “…Several studies have examined virulence genes in H. pylori from Bangladesh. We analyzed cagA and vacA subtypes and their association with severe histology phenotypes, and analyzed population types among Bangladeshi strains. …”
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    Two populations of less-virulent Helicobacter pylori genotypes in Bangladesh
  10. 1010
    “…Similarly, in patients infected with more virulent H. pylori strains bearing the vacA s1 genotype, primary clarithromycin resistance was significantly lower than in those infected with less virulent strains bearing the vacA s2 genotype, [41% (n = 32/78) vs 77.8% (n = 21/27) P = 0.0001]. …”
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    Can bacterial virulence factors predict antibiotic resistant Helicobacter pylori infection?
  11. 1011
    “…The most prevalent genotypes detected were VacA (75%), m1a (75%), s2 (70%) and m2 (65%), and cagA (60%). …”
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    Helicobacter pylori Strains Isolated from Raw Poultry Meat in the Shahrekord Region, Iran: Frequency and Molecular Characteristics
  12. 1012
    “…Infection by s1m1 vacA genotype was associated with increased antral and corpus gastritis. …”
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    Higher frequency of cagA EPIYA-C Phosphorylation Sites in H. pylori strains from first-degree relatives of gastric cancer patients
  13. 1013
    “…In this study, H. pylori was divided into four serotypes according to the presence and absence of CagA and VagA: type I; CagA(+) and VacA(+), type Ia; CagA(+) and VacA(−), type Ib; CagA(−) and VacA(+), and type II; CagA(−) and VacA(−). …”
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    Antigenic Diversity and Serotypes of Helicobacter pylori Associated with Peptic Ulcer Diseases
  14. 1014
    “…Samples were subjected to indirect immunofluorescence assay (IFA), 16S rRNA-based real-time PCR and vacA-based semi-nested PCR. Partial vacA gene sequences of H. pylori were compared between saliva and stool samples. …”
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    Detection and genotyping of Helicobacter pylori in saliva versus stool samples from asymptomatic individuals in Northeastern Thailand reveals intra-host tissue-specific H. pylori subtypes
  15. 1015
    “…The presence of the ureC, babA2, vacA and cagA genotypes was tested for in samples positive for H. pylori by multiplex polymerase chain reaction (Multiplex-PCR). …”
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    Helicobacter pylori in a poultry slaughterhouse: Prevalence, genotyping and antibiotic resistance pattern
  16. 1016
    “…Helicobacter pylori toxin, VacA, damages the gastric epithelium by erosion and loosening of tight junctions. …”
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    The Helicobacter pylori Vacuolating Toxin Inhibits T Cell Activation by Two Independent Mechanisms
  17. 1017
    Publicado 1999
    Tabla de Contenidos: “…La gallina ponedora. Cría de la vaca y el terreno.…”
    Libro
    Manual de agricultura y ganadería.
  18. 1018
    “…Thirty-six of the 50 clinical isolates (72%) were cagA positive, and 40 (80%) had the most virulent vacA genotype (s1/m1). Of the cagA positive strains, 94.4% were vacA s1/m1. …”
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    CagL polymorphisms D58/K59 are predominant in Helicobacter pylori strains isolated from Mexican patients with chronic gastritis
  19. 1019
    “…In addition, the rate of cagA, vacA, iceA1, and iceA2 virulence genes was determined. …”
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    Determination of Helicobacter pylori Virulence Genes in Gastric Biopsies by PCR
  20. 1020
    “…The seroprevalence of CagA+ and VacA+ strains was 77.4% and 58.5%, respectively, and type I(CagA+/VacA+) strains were significantly more common than type II(CagA-/VacA-) strains (59.7% vs 22.6%, p < 0.001). …”
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    Helicobacter pylori (H pylori) infection in Greece: the changing prevalence during a ten-year period and its antigenic profile
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