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1201por Azadegan-Dehkordi, Fatemeh, Bagheri, Nader, Shirzad, Mahsa, Sanei, Mohammad Hossein, Hashemzadeh-Chaleshtori, Morteza, Rafieian-Kopaei, Mahmoud, Tabatabaiefar, Mohammad Amin, Shirzad, Hedayatollah“…PATIENTS AND METHODS: Mucosal IL-6 mRNA levels was measured by real-time PCR using endoscopic biopsies taken from the gastric antrum of 58 subjects infected with H. pylori and 44 uninfected subjects. Presence of vacA and cagA virulence factors was evaluated using PCR. …”
Publicado 2015
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1202por Harrison, Ute, Fowora, Muinah A., Seriki, Abiodun T., Loell, Eva, Mueller, Susanna, Ugo-Ijeh, Margaret, Onyekwere, Charles A., Lesi, Olufunmilayo A., Otegbayo, Jesse A., Akere, Adegboyega, Ndububa, Dennis A., Adekanle, Olusegun, Anomneze, Ebere, Abdulkareem, Fatimah B., Adeleye, Isaac A., Crispin, Alexander, Rieder, Gabriele, Fischer, Wolfgang, Smith, Stella I., Haas, Rainer“…We found that the variability concerning the production of virulence factors between strains was minimal, with 96.4% of isolates being CagA-positive and 92.8% producing detectable VacA levels. In addition, high frequency of bacterial resistance was observed for metronidazole (99.1%), followed by amoxicillin (33.3%), clarithromycin (14.4%) and tetracycline (4.5%). …”
Publicado 2017
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1203por Macegoniuk, Katarzyna, Grela, Ewa, Biernat, Monika, Psurski, Mateusz, Gościniak, Grażyna, Dziełak, Anna, Mucha, Artur, Wietrzyk, Joanna, Berlicki, Łukasz, Grabowiecka, Agnieszka“…The biological relevance of the inhibitors was verified in vitro against a ureolytically active Escherichia coli Rosetta host that expressed H. pylori urease and against a reference strain, H. pylori J99 (CagA(+)/VacA(+)). The majority of the studied compounds exhibited urease-inhibiting activity in these whole-cell systems. …”
Publicado 2017
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1204por Valadan Tahbaz, Sahel, Yadegar, Abbas, Amirmozafari, Nour, Yaghoobee, Siamak, Ehsani Ardakani, Mohammad Javad, Zojaji, Homayoun“…Of 5 dental plaques positive for H. pylori, cagA gene was detected in 4 specimen, 3 in periodontitis group and one in non-periodontitis group. The H. pylori vacA s1m1 genotype was predominantly detected in 2/5 samples. …”
Publicado 2017
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1205“…METHODS: Human gastric epithelial cells (AGS) were infected by an Iranian H. pylori isolate (complete cagPAI, vacA s2m2, babA2, iceA1, sabA). The altered protein patterns separated by 2-DE were identified by matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF MS) analysis. …”
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1206Drug Therapeutic Failures as a Cause of Admission to an Intensive Care Unit at a University Hospitalpor Ruiz-Garzon, Jair Antonio, Rojas-Velandia, Camilo Andrés, Calderon-Ospina, Carlos-Alberto“…Information was collected by a resident in clinical toxicology, and each case was validated and analyzed by a research team using the algorithm proposed by Vaca González and Schumock and Thornton criteria for preventability to evaluate the existence of possible medication errors. …”
Publicado 2019
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1207por Elrais, Amina Mohamed, Arab, Walid S., Sallam, Khalid Ibrahim, Elmegid, Walaa Abd, Elgendy, Fatma, Elmonir, Walid, Imre, Kálmán, Morar, Adriana, Herman, Viorel, Elaadli, Haitham“…Multiplex PCR revealed that the virulence genes vacuolating cytotoxin A (vacA)s1, cytotoxin-associated gene A (cagA), and restriction endonuclease-replacing gene A (hrgA) were detected in 66.7%, 77.8%, and 100% of H. pylori strains tested, respectively. …”
Publicado 2022
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1208por Zhu, Yi, Lin, Chunhui, Xu, Huaming, Xia, Zhaoxin, Yang, Wensu, Tang, Hao, Hu, Xinyi, Jiang, Tong, Liu, Zhen, Shen, Jilu“…METHODS: To this end, we developed a molecular detection method based on RPA- CRISPR-Cas12a technology for the specific genes 16S rDNA gene, cytotoxin associated gene A(cagA), and vacuolating cytotoxin A (vacA) of H. pylori. RESULTS: The results of which were displayed by lateral flow strips. …”
Publicado 2023
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1209Publicado 2004Tabla de Contenidos: “…/ Angélica Peregrina -- La máquina de vapor / Mario Aldana Rendón -- Fundación de la Escuela Normal de Jalisco / Angélica Peregrina -- La llegada del arzobispo Orozco Jiménez / Francisco Javier Velázquez Fernández -- Aquel 8 de julio de 1914 / Mario Aldana Rendón -- Cristeros y cristeras / Agustín Vaca -- Las transformaciones del centro histórico / Arturo Camacho Becerra -- Un palacio para el Ayuntamiento / Arturo Camacho Becerra -- El 22 de abril de 1992 / José María Murià.…”
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1210por Moosavian, Mojtaba, Kushki, Elyas, Navidifar, Tahereh, Hajiani, Eskandar, Mandegari, Mahdi“…Also, to verify a hypothetical mouth-to-stomach infection route, the enzymatic digestions of three genes of cagA, vacA, and ureAB in H. pylori strains isolated from dental plaques and stomach samples were compared for each same case. …”
Publicado 2023
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1211por Gnad, Thorsten, Feoktistova, Maria, Leverkus, Martin, Lendeckel, Uwe, Naumann, Michael“…RESULTS: Infection of gastric epithelial NCI-N87 cells with H. pylori induces rapid phosphorylation of the Wnt/β-catenin pathway co-receptor LRP6 independent of the cytotoxin-associated gene A (CagA) or vacuolating cytotoxin A (VacA). However, bacteria lacking a functional type 4 secretion system (T4SS) failed to induce LRP6 phosphorylation. …”
Publicado 2010
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1212por Bisignano, Carlo, Filocamo, Angela, La Camera, Erminia, Zummo, Sebastiana, Fera, Maria Teresa, Mandalari, Giuseppina“…RESULTS: H. pylori strains were isolated from gastric biopsy samples following standard microbiology procedures. Also, cagA and vacA genes were identified using PCR. Susceptibility studies on 34 strains of H. pylori, including two reference strains (ATCC 43504, ATCC 49503), were performed by the standard agar dilution method. …”
Publicado 2013
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1213“…H. hepaticus is a close relative of H. pylori, but it lacks the major virulence factors of H. pylori including vacoulating cytotoxin A (VacA) and cytotoxin associated gene (cagA). Moreover, SabA, AlpA, and BabA, three important adhesin proteins of H. pylori, are absent in its genome. …”
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1214por Yahaghi, Emad, Khamesipour, Faham, Mashayekhi, Fatemeh, Safarpoor Dehkordi, Farhad, Sakhaei, Mohammad Hossein, Masoudimanesh, Mojtaba, Khameneie, Maryam Khayyat“…The most prevalent virulence genes were oipA (86.44%) and cagA (57.625). VacA s1a (37.28%) and iceA1 (47.45%) were the most prevalent genotypes. …”
Publicado 2014
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1215por Kumar, Narender, Mariappan, Vanitha, Baddam, Ramani, Lankapalli, Aditya K., Shaik, Sabiha, Goh, Khean-Lee, Loke, Mun Fai, Perkins, Tim, Benghezal, Mohammed, Hasnain, Seyed E., Vadivelu, Jamuna, Marshall, Barry J., Ahmed, Niyaz“…Our analyses identified a few strain-specific genes encoding restriction modification systems and outlined 311 core genes possibly under differential evolutionary constraints, among the strains representing different ethnic groups. The cagA and vacA genes also showed variations in accordance with the host genetic background of the strains. …”
Publicado 2015
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1216por Bagheri, Nader, Azadegan-Dehkordi, Fatemeh, Shirzad, Mahsa, Zamanzad, Benham, Rahimian, Ghorbanali, Taghikhani, Afshin, Rafieian-Kopaei, Mahmoud, Shirzad, Hedayatollah“…Mucosal IL-21 mRNA expression level in H. pylori-infected and uninfected gastric biopsy was determined by real-time PCR. The presence of vacA (vacuolating cytotoxin A) and cagA (cytotoxin associated gene A) virulence factors were evaluated using PCR. …”
Publicado 2015
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1217“…The predominant genotype of H. pylori in Korea has been reported as cagA(+), vacA s1b, m2, iceA genotype. Present study aims to investigate whether NADPH oxidase-generated ROS mediate apoptosis in human gastric epithelial AGS cells infected with H. pylori in a Korean isolate. …”
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1218por Jin, Dong Zhu, Jung, Hyun Chae, Kim, Jung Mogg, Kim, Joo Sung, Song, In Sung, Kim, Chung Yong“…OBJECTIVES: Considering the geographic differences in the prevalence of virulence factors such as CagA or VacA of H. pylori isolated from Korean adults compared with those from western countries, the establishment of a mouse model infected with H. pylori isolated from Korean adults is needed to investigate the pathogenesis and to develop vaccines against H. pylori infection in Korea. …”
Publicado 1999
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1219“…Although a number of putative virulence factors have been identified including cytotoxin-associated gene a (cagA) and vacA, there are conflicting data about their actual participation as specific risk factor for H. pylori-related diseases. …”
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1220por Binh, Tran Thanh, Tuan, Vo Phuoc, Dung, Ho Dang Quy, Tung, Pham Huu, Tri, Tran Dinh, Thuan, Ngo Phuong Minh, Tam, Le Quang, Nam, Bui Chi, Giang, Do Anh, Hoan, Phan Quoc, Uchida, Tomohisa, Trang, Tran Thi Huyen, Khien, Vu Van, Yamaoka, Yoshio“…H. pylori status was determined by multiple tests (rapid urease test, culture, histology, and serology). cagA and vacA genotypes were determined by PCR-based sequencing. …”
Publicado 2018
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