Mostrando 21 - 40 Resultados de 40 Para Buscar '"vaccinologist"', tiempo de consulta: 0.74s Limitar resultados
  1. 21
    “…Today, vaccinologists have come to understand that the hallmark of any protective immune response is the antigen. …”
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    Designs of Antigen Structure and Composition for Improved Protein-Based Vaccine Efficacy
  2. 22
    “…In the end, the given findings may help the experimental vaccinologists to develop a very potent and effective peptide-based vaccine.…”
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    Designing a Novel Peptide-Based Multi-Epitope Vaccine to Evoke a Robust Immune Response against Pathogenic Multidrug-Resistant Providencia heimbachae
  3. 23
    “…Thepre-Pasteurian vaccinologists, paved the way for the actual history of rabies vaccines with the development of first generation vaccines. …”
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    Developments in Rabies Vaccines: The Path Traversed from Pasteur to the Modern Era of Immunization
  4. 24
    por Van Regenmortel, Marc H. V.
    Publicado 2014
    “…A major reason is the belief shared by many vaccinologists that antibodies possess a narrow specificity for a single epitope and are not polyspecific for a diverse group of potential epitopes. …”
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    An Outdated Notion of Antibody Specificity is One of the Major Detrimental Assumptions of the Structure-Based Reverse Vaccinology Paradigm, Which Prevented It from Helping to Develop an Effective HIV-1 Vaccine
  5. 25
    “…METHODS: Following a review of the literature, and with the active participation of representatives from the World Allergy Organization (WAO), the European Academy of Allergy and Clinical Immunology (EAACI), the American Academy of Allergy, Asthma, and Immunology (AAAAI), and the American College of Allergy, Asthma, and Immunology (ACAAI), the final committee was formed with the purpose of having members who represented a wide-range of countries, had previously worked on vaccine safety, and included both allergist/immunologists as well as vaccinologists. RESULTS: Consensus was reached on a variety of topics, including: definition of immediate allergic reactions, including anaphylaxis, approaches to distinguish association from causality, approaches to patients with a history of an allergic reaction to a previous vaccine, and approaches to patients with a history of an allergic reaction to components of vaccines. …”
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    International Consensus (ICON): allergic reactions to vaccines
  6. 26
    “…BACKGROUND: Toward the goals of providing an additional vector to add to the armamentarium available to HIV vaccinologists and of creating a bivalent vaccine effective against dengue virus and HIV, we have attempted to create vectors which express dengue virus non-structural proteins and HIV immunogens. …”
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    Development of dengue virus replicons expressing HIV-1 gp120 and other heterologous genes: a potential future tool for dual vaccination against dengue virus and HIV
  7. 27
    “…Over the past 20 years, vaccinologists, bioinformatics experts, and advanced programmers based in Providence, Rhode Island, USA have advanced the development of an integrated toolkit for vaccine design called iVAX, that is secure and user-accessible by internet. …”
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    Better Epitope Discovery, Precision Immune Engineering, and Accelerated Vaccine Design Using Immunoinformatics Tools
  8. 28
    “…To foster collaboration among leading vaccinologists, government, policy makers, industry partners, and funders from around the world, the Precision Vaccines Program at Boston Children’s Hospital hosted the 2(nd) International Precision Vaccines Conference (IPVC) at Harvard Medical School on the 17(th)–18(th) October 2019. …”
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    Towards Precision Vaccines: Lessons From the Second International Precision Vaccines Conference
  9. 29
    “…Recent advances in the discovery and delivery of Toll-like receptor (TLR) agonist adjuvants have provided a new toolbox for vaccinologists. Prominent among these candidate adjuvants are synthetic small molecule TLR7/8 agonists. …”
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    Development of a TLR7/8 agonist adjuvant formulation to overcome early life hyporesponsiveness to DTaP vaccination
  10. 30
    por Salod, Zakia, Mahomed, Ozayr
    Publicado 2022
    “…We recommend that vaccinologists use these findings as a guide to performing experimental validation for various viruses, with SARS-CoV-2 as a priority, because better vaccines are needed, especially to stay ahead of the emergence of new variants. …”
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    Mapping Potential Vaccine Candidates Predicted by VaxiJen for Different Viral Pathogens between 2017–2021—A Scoping Review
  11. 31
    “…This calls for new and accessible approaches to training vaccinologists in Africa where the demand is high. METHODS: The aim of this proof-of-concept study was to ascertain the training needs of alumni of the Annual African Vaccinology Course and assess the effectiveness of an online webinar series in meeting those needs. …”
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    Expanding the reach of vaccinology training in Africa: leveraging the success of the Annual African Vaccinology Course
  12. 32
    por Van Regenmortel, Marc H. V.
    Publicado 2018
    “…Hypotheses and theories are essential constituents of the scientific method. Many vaccinologists are unaware that the problems they try to solve are mostly inverse problems that consist in imagining what could bring about a desired outcome. …”
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    Development of a Preventive HIV Vaccine Requires Solving Inverse Problems Which Is Unattainable by Rational Vaccine Design
  13. 33
    “…In conclusion, the data reported herein might help vaccinologists to formulate a chimeric vaccine against the aforementioned target pathogen.…”
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    Novel Chimeric Vaccine Candidate Development against Leptotrichia buccalis
  14. 34
    “…The generation of effective levels of antigen-specific immunity at the mucosal sites of pathogen entry is a key goal for vaccinologists. We explored topical vaginal application as an approach to initiate local antigen-specific immunity, enhance previously existing systemic immunity or re-target responses to the mucosae. …”
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    Intravaginal immunisation using a novel antigen-releasing ring device elicits robust vaccine antigen-specific systemic and mucosal humoral immune responses
  15. 35
    “…Targeted ablation of native GnRH-I by genetic immunization could offer leverage to vaccinologists, seeking therapeutic target to control and prevent malignancy of prostate.…”
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    Plasmid DNA vaccine coding eight repeats of gonadotrophin-releasing hormone induced atrophy of prostate in male mice
  16. 36
    “…Briefly, findings of the current study are promising and may help experimental vaccinologists to formulate a novel multi-epitope vaccine against P. rettgeri.…”
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    Designing a Recombinant Vaccine against Providencia rettgeri Using Immunoinformatics Approach
  17. 37
    “…The concept of donor-unrestricted T cells (DURTs) comprises a heterogeneity of lymphoid cells that respond to an abundance of unconventional epitopes in a non-MHC-restricted manner. Vaccinologists strive to harness this so far underexplored branch of the immune system for new vaccines against tuberculosis. …”
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    Phosphatidylinositolmannoside vaccination induces lipid-specific Th1-responses and partially protects guinea pigs from Mycobacterium tuberculosis challenge
  18. 38
    “…Thus, understanding the antigenic relationships between influenza viruses that have circulated is important to both vaccinologists and immunologists. RESULTS: Here we develop a method of mapping antigenic relationships between influenza virus stains using a sequence-based antigenic distance approach (SBM). …”
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    Antigenic cartography of H1N1 influenza viruses using sequence-based antigenic distance calculation
  19. 39
    “…Finally, these findings may aid experimental vaccinologists in developing a very potent hantavirus vaccine.…”
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    Design of a Multi-Epitopes Vaccine against Hantaviruses: An Immunoinformatics and Molecular Modelling Approach
  20. 40
    “…These results may help experimental vaccinologists design a potent MPX vaccine.…”
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    Contriving multi-epitope vaccine ensemble for monkeypox disease using an immunoinformatics approach
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