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7041por Whittaker, Konrad, Guggenberger, Konstanze, Venhoff, Nils, Doostkam, Soroush, Schaefer, Hans-Eckart, Fritsch, Brita“…In contrast to earlier reports of cerebral manifestations in CD, our patient showed no coincident gastrointestinal symptoms indicating an activity of CD during the progression of cortical lesion load, suggesting that similar to other extra-intestinal manifestations in CD, the activity of gastrointestinal symptoms does not necessarily reflect the activity of CD associated cerebral vasculitis. Therefore, diagnosis and therapy of cerebral manifestation may be delayed when focusing on gastrointestinal symptoms alone.…”
Publicado 2018
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7042por Rhee, Rennie L., Holweg, Cecile T. J., Wong, Kit, Cuthbertson, David, Carette, Simon, Khalidi, Nader A., Koening, Curry L., Langford, Carol A., McAlear, Carol A., Monach, Paul A., Moreland, Larry W., Pagnoux, Christian, Seo, Philip, Specks, Ulrich, Sreih, Antoine G., Ytterberg, Steven R., Merkel, Peter A.“…METHODS: Participants enrolled in a multicenter, prospective cohort of patients with EGPA were included in this study if they had disease activity (defined as Birmingham Vasculitis Activity Score [BVAS] > 0) during follow-up. …”
Publicado 2018
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7043por Wang, Jiaqi, An, Feimeng, Cao, Yuju, Gao, Hongyan, Sun, Mingqi, Ma, Chao, Wu, Hao, Zhang, Baoxin, Liu, Wanlin, Wang, Jianzhong“…As an endogenous inhibitor of matrix metalloproteinases (MMPs) in the extracellular matrix, the expression of tissue inhibitors of metalloprotease-4 (TIMP4) plays an essential role in cartilage and bone tissue damage and remodeling, vasculitis formation, intravascular thrombosis, and lipid metabolism. …”
Publicado 2019
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7044por Arai, Ayako“…However, patients with an active disease, in which the condition is accompanied by fever, liver dysfunction, progressive skin lesions, vasculitis, or uveitis, had worse outcomes after allo-HSCT, than patients with an inactive disease had. …”
Publicado 2019
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7045por Boehm, Michael, Bonthuis, Marjolein, Noordzij, Marlies, Harambat, Jérôme, Groothoff, Jaap W., Melgar, Ángel Alonso, Buturovic, Jadranka, Dusunsel, Ruhan, Fila, Marc, Jander, Anna, Koster-Kamphuis, Linda, Novljan, Gregor, Ortega, Pedro J., Paglialonga, Fabio, Saravo, Maria T., Stefanidis, Constantinos J., Aufricht, Christoph, Jager, Kitty J., Schaefer, Franz“…RESULTS: Three hundred ninety-three (55.1%) of 713 children started HD with a CVC and were more often females, younger, had more often an unknown diagnosis, glomerulonephritis, or vasculitis, and lower hemoglobin and height-SDS at HD initiation. …”
Publicado 2018
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7046por Czopek, Alicja, Moorhouse, Rebecca, Guyonnet, Léa, Farrah, Tariq, Lenoir, Olivia, Owen, Elizabeth, van Bragt, Job, Costello, Hannah M, Menolascina, Filippo, Baudrie, Véronique, Webb, David J, Kluth, David C, Bailey, Matthew A, Tharaux, Pierre-Louis, Dhaun, Neeraj“…In patients with small vessel vasculitis, the impacts of Mφ depleting and non-depleting therapies on blood pressure (BP) and endothelial function were examined. …”
Publicado 2019
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7047“…OBJECTIVES: We investigated the reliability of the cobalt-chromium (CoCr) synovial joint fluid ratio (JFR) in identifying the presence of a severe aseptic lymphocyte-dominated vasculitis-associated lesion (ALVAL) response and/or suboptimal taper performance (SOTP) following metal-on-metal (MoM) hip arthroplasty. …”
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7048por Maritati, Federica, Rocco, Rossana, Accorsi Buttini, Eugenia, Marvisi, Chiara, Nicastro, Maria, Urban, Maria L., Fenaroli, Paride, Peyronel, Francesco, Benigno, Giuseppe D., Palumbo, Alessandro A., Corradi, Domenico, Emmi, Giacomo, Pipitone, Nicolò, Palmisano, Alessandra, Vaglio, Augusto“…We also tested the diagnostic significance of IgG4 by comparing its levels in CP patients, healthy and disease controls (malignancies, Erdheim-Chester disease, large-, and small-vessel vasculitis). Results: We studied 113 consecutive patients with active CP. …”
Publicado 2019
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7049por Han, Yeeun, Jin, So-Young, Kim, Dong Won, Jeen, Yoon Mi, Kim, Yon Hee, Choi, In Ho“…In U-GIT, extravasted red blood cell (RBC) (14/19) was the most common histologic finding, while leukocytoclastic vasculitis (LCV)/capillarities were identified in 7 specimens, including 5 duodenum samples. …”
Publicado 2019
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7050por Bruschi, Maurizio, Petretto, Andrea, Santucci, Laura, Vaglio, Augusto, Pratesi, Federico, Migliorini, Paola, Bertelli, Roberta, Lavarello, Chiara, Bartolucci, Martina, Candiano, Giovanni, Prunotto, Marco, Ghiggeri, Gian Marco“…NET proteins are recognized as autoantigens in ANCA vasculitis; limited knowledge is available in other autoimmune pathologies. …”
Publicado 2019
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7051por Criado, Paulo Ricardo, Maruta, Celina Wakisaka, Alchorne, Alice de Oliveira de Avelar, Ramos, Andréa Machado Coelho, Gontijo, Bernardo, dos Santos, Josemir Belo, Martins, Luis Eduardo Agner Machado, Rivitti-Machado, Maria Cecília, Silvares, Maria Regina Cavariani, Pires, Mario Cezar, de Souza, Patricia Karla, Orfali, Raquel Leão, Bonamigo, Renan Rangel, Bedrikow, Roberta Buense, Criado, Roberta Fachini Jardim, de Oliveira, Zilda Najjar Prado“…Biopsy of skin lesion and histopathology may be indicated to rule out other diseases, such as, urticarial vasculitis. Other laboratory tests, such as complete blood count, CRP, ESR and thyroid screening. …”
Publicado 2019
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7052por Park, Hee Jin, Park, Jun Yong, Jung, Seung Min, Song, Jason Jungsik, Park, Yong-Beom, Lee, Sang-Won“…Conventional risk factors included old age (≥ 65 years), male gender, diabetes mellitus (DM) and hypertension (HTN) at diagnosis, and disease-related risk factor included GPA, antineutrophil cytoplasmic antibody, Birmingham vasculitis activity score (BVAS) and five factor score (FFS (2009)). …”
Publicado 2019
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7053por Ladhani, Shamez N., Campbell, Helen, Lucidarme, Jay, Gray, Steve, Parikh, Sydel, Willerton, Laura, Clark, Stephen A., Lekshmi, Aiswarya, Walker, Andrew, Patel, Sima, Bai, Xilian, Ramsay, Mary, Borrow, Ray“…Six patients had inherited complement deficiencies, two had immune-mediated conditions associated with complement deficiency (glomerulonephritis and vasculitis), and eight others were on Eculizumab therapy, five for paroxysmal nocturnal haemoglobinuria and three for atypical haemolytic uraemic syndrome. …”
Publicado 2019
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7054“…Due to persistent radiological abnormalities a temporal lobe biopsy was performed which showed marked astrocytic gliosis without evidence of vasculitis, inflammation, infarction or neoplasia. A diagnosis of metabolic encephalopathy secondary to DKA was reached. …”
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7055“…The main mechanisms proposed for methadone induced hearing loss are cochlear ischemia following vasospasm or vasculitis, direct effect of opioids on opioid receptors present in cochlear stria vascularis of inner ear, blood-labyrinth selective transport of opioidproteins and receptors, and genetic polymorphism and mutations. …”
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7056por van Sleen, Yannick, Sandovici, Maria, Abdulahad, Wayel H, Bijzet, Johan, van der Geest, Kornelis S M, Boots, Annemieke M H, Brouwer, Elisabeth“…OBJECTIVE: GCA, a systemic vasculitis, is characterized by an IL-6-dependent acute-phase response. …”
Publicado 2019
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7057“…These include rheumatoid arthritis, vasculitis, and connective tissue diseases, as well as many other pathological conditions of the immune system. …”
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7058por Navaratnarajah, Arunraj, Sambasivan, Khrishanthne, Cook, Terry H, Pusey, Charles, Roufosse, Candice, Willicombe, Michelle“…A histological diagnosis of primary GN (P = 0.001) or tubulointerstitial nephritis (P = 0.008) was associated with a favourable renal outcome, while patients with vasculitis and paraprotein-related renal disease (PPRD) had the highest risk of requiring dialysis (P = 0.0002 and P = 0.003, respectively). …”
Publicado 2019
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7059“…Test for anti-neutrophil cytoplasmic antibodies (ANCA) was positive, and so the nephrologist and rheumatologist agreed on a diagnosis of ANCA-associated vasculitis, with renal and pulmonary involvement and acute renal failure. …”
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7060por Khojah, Amer M., Miller, Michael L., Klein-Gitelman, Marisa S., Curran, Megan L., Hans, Victoria, Pachman, Lauren M., Fuleihan, Ramsay L.“…The occurrence of hypogammaglobulinemia varied based on the rituximab indication: 46% pediatric Systemic Lupus Erythematosus (SLE), 71% autoimmune CNS disease, 60% ANCA vasculitis, and 12% in the miscellaneous group. Autoimmune CNS disease had more severe hypogammaglobulinemia, more persistent and was associated with more frequent or severe infections. …”
Publicado 2019
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