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1401por Feng, Zhuoying, Zhou, Fanghang, Tan, Miaomiao, Wang, Tingting, Chen, Ying, Xu, Wenwen, Li, Bin, Wang, Xin, Deng, Xin, He, Ming-Liang“…More interestingly, depleting the writers and readers by siRNAs inhibited virus replication and reproduction; whereas depleting the erasers promoted viral replication and reproduction. …”
Publicado 2021
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1402por Tingting, Zhang“…OBJECTIVE: On the basis of inheriting the classical aesthetic orientation of Japanese literature, contemporary Japanese literature changes the creative methods of traditional Japanese writers, strives to transcend the national limitations of Japanese literature, and strives to capture literary materials with a “modern feel.” …”
Publicado 2022
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1403“…Factors introducing, deleting, or interpreting specific modifications have been identified, and analogous with epigenetic terminology, have been designated “writers,” “erasers,” and “readers.” Such modifications in the transcriptome are referred to as epitranscriptomic changes and represent a fascinating new layer of gene expression regulation that has only recently been appreciated. …”
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1404por Kennedy, Ann Blair“…Having a formalized mechanism for linking novice authors and experienced authors can assist budding writers. Scientific writing is a skill that many practitioners are not taught in school as this type of writing is not generally used in clinical practice. …”
Publicado 2017
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1405por Hu, Bin-bin, Wang, Xiao-yan, Gu, Xu-Yu, Zou, Chen, Gao, Zhen-jun, Zhang, Heng, Fan, Yu“…As the most common form of RNA modification, m(6)A methylation has attracted increasing research interest in recent years. m(6)A is catalysed by RNA methyltransferases METTL3, METTL14 and WTAP (writers), m(6)A is removed by the demethylases FTO and ALKBH5 (erasers) and interacts with m6A-binding proteins, such as YT521-B homology (YTH) domain-containing proteins. …”
Publicado 2019
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1406por Xu, Haojun, Lin, Changjie, Yang, Jinghan, Chen, Xi, Chen, Yingyu, Chen, Jianguo, Guo, Aizhen, Hu, Changmin“…N(6)-Methyladenosine (m(6)A) is the most abundant epigenetic RNA modification in eukaryotes, regulating RNA metabolism (export, stability, translation, and decay) in cells through changes in the activity of writers, erasers, and readers and ultimately affecting human life or disease processes. …”
Publicado 2022
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1407“…Aristotles subject here is time, and his treatment of it had led to controversy in earlier writers. Philoponus does offer novelties when he treats motion round a bend as in one sense faster than motion on the straight over the same distance in the same time, because of the need to consider the greater effort involved. …”
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1408“…African philosophies, thinkers, writers and ways of healing are not practiced widely in healthcare throughout the globe. …”
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1409por Skuse, Alanna“…However, such explanations proved inadequate to make sense of the condition's malignancy, and medical writers frequently constructed cancer as quasi-sentient, zoomorphising the disease as an eating worm or wolf. …”
Publicado 2014
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1410“…This modification is installed by the m(6)A methylation “writers” and can be reversed by demethylases that serve as “erasers.” …”
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1411“…In this review, we summarize typical features of methylated transcriptome in mammals, and highlight the ‘writers’, ‘erasers’ and ‘readers’ of m(6)A RNA modification. …”
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1412por O’Sullivan, Julia, Tedim Ferreira, Maria, Gagné, Jean-Philippe, Sharma, Ajit K., Hendzel, Michael J., Masson, Jean-Yves, Poirier, Guy G.“…It is modulated through a dynamic interplay between ADP-ribose readers, writers and erasers. While ADP-ribose synthesis has been studied and reviewed extensively, ADP-ribose processing by erasing enzymes has received comparably less attention. …”
Publicado 2019
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1413“…In this review, we summarize the writers, erasers and readers of lysine crotonylation, and their physiological functions, including gene transcription, acute kidney injury, spermatogenesis, depression, telomere maintenance, HIV latency and cancer process. …”
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1414por Huang, Jiali, Chen, Zhenyao, Chen, Xin, Chen, Jun, Cheng, Zhixiang, Wang, Zhaoxia“…Therefore, in this review, we describe the role of methyltransferases as m(6)A writers in cancer and summarize their potential molecular mechanisms of action.…”
Publicado 2021
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1415“…Phosphotyrosine-containing compounds attract significant attention due to their potential to modulate signalling pathways by binding to phospho-writers, erasers and readers such as SH2 and PTB domain containing proteins. …”
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1416por Feoli, Alessandra, Viviano, Monica, Cipriano, Alessandra, Milite, Ciro, Castellano, Sabrina, Sbardella, Gianluca“…Protein lysine methyltransferases constitute a large family of epigenetic writers that catalyse the transfer of a methyl group from the cofactor S-adenosyl-l-methionine to histone- and non-histone-specific substrates. …”
Publicado 2021
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1417por Zhu, Yong-fu, Wang, Shu-Jie, Zhou, Jie, Sun, Ye-han, Chen, You-mou, Ma, Jia, Huo, Xing-xing, Song, Hang“…N(6)-methyladenosine (m(6)A) is a major internal epigenetic modification in eukaryotic mRNA, which is dynamic and reversible. m(6)A is regulated by methylases (“writers”) and demethylases (“erasers”) and is recognized and processed by m(6)A-binding proteins (“readers”), which further regulate RNA transport, localization, translation, and degradation. …”
Publicado 2022
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1418“…N(6)-Methyladenosine (m(6)A) is the most abundant modification on eukaryote messenger RNA and plays a key role in posttranscriptional regulation of RNA metabolism including splicing, intracellular transport, degradation, and translation. m(6)A is dynamically regulated by methyltransferases (writers), RNA-binding proteins (readers), and demethylases (erasers). …”
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1419por Liu, Yuhuan“…As one of the most outstanding female writers in post-war Britain, Doris Lessing, winner of the Nobel Prize for Literature, has a strong spirit of the times in her works. …”
Publicado 2022
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1420por Li, Gaofeng, Fu, Qiru, Liu, Cong, Peng, Yuxi, Gong, Jun, Li, Shilan, Huang, Yan, Zhang, Haiyuan“…N6-methyladenosinen (m(6)A) methylation is a frequent RNA methylation modification that is regulated by three proteins: “writers”, “erasers”, and “readers”. The m(6)A modification regulates RNA stability and other mechanisms, including translation, cleavage, and degradation. …”
Publicado 2022
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