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1por Takahashi, Tatsunori, Sakai, Noriaki, Iwasaki, Tomonori, Doyle, Timothy C., Mobley, William C., Nishino, Seiji“…This study, thus, aimed to quantitatively characterize the upper airway as well as craniofacial abnormalities in Dp(16)1Yey (Dp16) mice. Dp16 mice demonstrated craniofacial hypoplasia, especially in the ventral part of the skull and the mandible, and rostrally positioned hyoid. …”
Publicado 2020
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2por Raveau, Matthieu, Polygalov, Denis, Boehringer, Roman, Amano, Kenji, Yamakawa, Kazuhiro, McHugh, Thomas J“…Here, using in vivo recording in the Dp(16)1Yey model, we find alterations in the organization of spiking of hippocampal CA1 pyramidal neurons, including deficits in the generation of complex spikes. …”
Publicado 2018
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3“…In this study, sleep and electroencephalography (EEG) oscillations were recorded from aged (12–14 mos.) Dp(16)1Yey/+ mice (Dp16), a mouse model of DS. We observed disrupted sleep demonstrated by increased activity during the dark phase and increased time awake at the expense of NREM sleep compared to wild-type mice. …”
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4por Aziz, Nadine M., Guedj, Faycal, Pennings, Jeroen L. A., Olmos-Serrano, Jose Luis, Siegel, Ashley, Haydar, Tarik F., Bianchi, Diana W.“…Interestingly, Dp(16)1/Yey mice showed no abnormalities in prenatal brain phenotypes, yet they manifested behavioral deficits starting at postnatal day 15 that continued through adulthood. …”
Publicado 2018
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