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  1. 1641
    “…Here, we discuss our RNA interference (RNAi) pipeline for cancer target discovery based on our optimized short-hairpin RNA (shRNA) tools for negative selection screens and inducible RNAi platform that, in combination with embryonic stem cell (ESC)-based genetically engineered mouse models (GEMMs), enable deep in vivo target validation.…”
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    A Pipeline for Drug Target Identification and Validation
  2. 1642
    “…As alignment algorithms report gap-sites with a considerable false discovery rate, validations are required. We describe two quality scores, gap quality score (gqs) and weighted gap information score (wgis), developed for validation of putative splicing events: While gqs solely relies on alignment data wgis additionally considers information from the genomic sequence. …”
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    Validation of Splicing Events in Transcriptome Sequencing Data
  3. 1643
    por Kuzmanovic, Bojana, Rigoux, Lionel
    Publicado 2017
    “…Finally, in this specific experimental context, the approach based on reinforcement learning was superior to the Bayesian approach. The computational validation of valence-dependent belief updating represents a novel support for a genuine optimism bias in human belief formation. …”
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    Valence-Dependent Belief Updating: Computational Validation
  4. 1644
    “…BACKGROUND: The development and validation study of the Clinical Chronic Obstructive Disease (COPD) Questionnaire (CCQ) has recently been published in this journal. …”
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    Validation of the Clinical COPD questionnaire in Italian language
  5. 1645
    “…METHODS: In October 2015, we conducted a retrospective review of KCR by validating the internal consistency of registry records with medical and pathology records. …”
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    Online Artículo Texto
    Validation and Quality Assessment of the Kilimanjaro Cancer Registry
  6. 1646
    “…Despite some inconclusive experimental evidences for the vibrational model of olfaction, the validity of the model has not been examined yet and therefore it suffers from the lack of conclusive experimental support. …”
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    Validity Examination of the Dissipative Quantum Model of Olfaction
  7. 1647
    “…These indicators are statistically independent, and so can be combined quantitatively into a single probability calculation. We validate this calculation: recently isolated mutations that were not in the training set for developing the indicators, with high calculated probability of causality, are confirmed in every case by additional genetic data to indeed be causative. …”
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    Validated Bayesian Differentiation of Causative and Passenger Mutations
  8. 1648
    “…OBJECTIVE: to develop, evaluate and validate a surgical safety checklist for patients in the pre and postoperative periods in surgical hospitalization units. …”
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    Online Artículo Texto
    Safe surgery: validation of pre and postoperative checklists
  9. 1649
    “…Affinity purified antibodies were used for immunoassays development and assays validated using serum from OA patients and controls. …”
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    Development and validation of novel biomarker assays for osteoarthritis
  10. 1650
    “…This review examines two important aspects that are central to modern big data bioinformatics analysis – software scalability and validity. We argue that not only are the issues of scalability and validation common to all big data bioinformatics analyses, they can be tackled by conceptually related methodological approaches, namely divide-and-conquer (scalability) and multiple executions (validation). …”
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    Scalability and Validation of Big Data Bioinformatics Software
  11. 1651
    “…To assess the validity of Vasoactive-Inotropic Score as a scoring system for cardiovascular support and surrogate outcome in pediatric sepsis. …”
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    Validation of the Vasoactive-Inotropic Score in Pediatric Sepsis*
  12. 1652
    “…PURPOSE: To validate diagnostic codes for hypertrophic cardiomyopathy (HCM), analyze misclassfications, and estimate the prevalence of HCM in an unselected Swedish regional cohort. …”
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    Misclassification of hypertrophic cardiomyopathy: validation of diagnostic codes
  13. 1653
    “…The study aimed to provide evidence of the psychometric properties, reliability, and validity of the Measure of Absorption in Sport Contexts (MASCs). …”
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    Absorption in Sport: A Cross-Validation Study
  14. 1654
    “…We investigated the validity and reliability of four language mapping paradigms that may be appropriate for individuals with acquired aphasia: sentence completion, picture naming, naturalistic comprehension, and narrative comprehension. …”
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    Validity and reliability of four language mapping paradigms
  15. 1655
    por Lindgaard, Karsten, Riisgaard, Lars
    Publicado 2017
    “…SETTING: Patients were recruited and initially scanned in general practice. The validation examinations were conducted in a hospital setting. …”
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    ‘Validation of ultrasound examinations performed by general practitioners’
  16. 1656
    “…OBJECTIVE: to elaborate and validate a checklist to identify compliance with the recommendations for the structure of medication prescriptions, based on the Protocol of the Ministry of Health and the Brazilian Health Surveillance Agency. …”
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    Elaboration and Validation of the Medication Prescription Safety Checklist
  17. 1657
    “…Validation of indications was done via chart review evaluating microbiology results. …”
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    Validation and Evaluation of Antimicrobial Orders Indication for Use
  18. 1658
    por Schaper, Niclas
    Publicado 2017
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    Why is it necessary to validate models of pedagogical competency?
  19. 1659
    “…The aim of this study was to validate the prognostic value of the Moffitt’s classifications and to compare the Collisson’s, Moffitt’s, and Bailey’s classifications in a large series of samples. …”
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    Validation and comparison of the molecular classifications of pancreatic carcinomas
  20. 1660
    por Chojnicka, Izabela, Pisula, Ewa
    Publicado 2017
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    Adaptation and Validation of the ADOS-2, Polish Version
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