Mostrando 21 - 40 Resultados de 85 Para Buscar '1. A SKL', tiempo de consulta: 0.23s Limitar resultados
  1. 21
    Publicado 1993
    “…One of them resides at the extreme carboxy terminus constituting a new variant of this signal, -SSNSKF, not active in monkey kidney cells (Gould, S. …”
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    Two independent peroxisomal targeting signals in catalase A of Saccharomyces cerevisiae
  2. 22
    Publicado 1991
    “…Cell Biol. 108:1657-1664). Antibodies raised to a peptide ending in this sequence (SKL-COOH) recognize a number of peroxisomal proteins. …”
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    Evolutionary conservation of a microbody targeting signal that targets proteins to peroxisomes, glyoxysomes, and glycosomes
  3. 23
    “…Results: There were 45 cases (35.2%) of all-cause death and 36 cases (28.1%) of CVD mortality. Multivariate linear regression analysis showed that Log[iPTH] (γ = −0.224, P = 0.015) was an independent predictor of sKL level. …”
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    A Decreased Level of Soluble Klotho Can Predict Cardiovascular Death in No or Mild Abdominal Aortic Calcification Hemodialysis Patients
  4. 24
    “…Matching was done in a ratio 1:4, based on T-stage (size of the tumour) and year of diagnosis +/−5 years. …”
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    No increased risk of relapse of breast cancer for women who give birth after assisted conception
  5. 25
    “…In a xenograft model, administration of viral particles carrying sKL, a spliced klotho isoform containing the KL1 domain, inhibited pancreatic tumors. …”
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    A Transgenic Model Reveals the Role of Klotho in Pancreatic Cancer Development and Paves the Way for New Klotho-Based Therapy
  6. 26
    “…However, SKL2001 could improve the proliferation and mineralization abilities and ALP activity of MC3T3-E1 cells. …”
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    Catalpol Promotes the Proliferation and Differentiation of Osteoblasts Induced by High Glucose by Inhibiting KDM7A
  7. 27
    “…TAM (20 mg day(−1)) with concomitant RT was prescribed in 90 hormone receptor-positive patients. …”
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    Concomitant use of tamoxifen with radiotherapy enhances subcutaneous breast fibrosis in hypersensitive patients
  8. 28
    por Li, Qingfang, Zan, Lingling
    Publicado 2022
    “…Gene set enrichment analysis identified the pathway responsible for the effects of ATG4A. The protein expression of ATG4A, LC3, p62, Bcl-2, Bax, GSK-3β, phosphorylated (p)-GSK-3β, β-catenin, cyclinD1 and c-myc in MCF and MCF7/R cells was determined using western blot. …”
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    Knockdown of ATG4A inhibits breast cancer progression and promotes tamoxifen chemosensitivity by suppressing autophagy
  9. 29
    Publicado 1996
    “…Second, the human catalase PTS comprises more than the COOH-terminal three amino acids, in that COOH-terminal-ANL cannot functionally replace the PTS1 signal-SKL in targeting a chloramphenicol acetyl transferase fusion protein to peroxisomes. …”
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    Targeting of human catalase to peroxisomes is dependent upon a novel COOH-terminal peroxisomal targeting sequence
  10. 30
    “…Specifically, LIG might act as a potent enhancer of α-secretase, disintegrin, and metalloprotease 10 (ADAM10), leading to upregulation of alpha-processing of both APP and Klotho and subsequent increases in the levels of both soluble APP fragment (sAPPα) and soluble Klotho (sKL) with inhibition of IGF-1/Akt/mTOR signaling in AD mice and cultured cells. …”
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    Neuroprotective Effect of Ligustilide through Induction of α-Secretase Processing of Both APP and Klotho in a Mouse Model of Alzheimer’s Disease
  11. 31
    “…The optimized CNC suspensions were used for incorporating alkaline lignin (AL) and softwood kraft lignin (SKL) in various concentrations (1–10 wt %). Morphological characterization showed homogeneity of the lignin distribution in CNC/lignin films. …”
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    Transparent and Homogenous Cellulose Nanocrystal/Lignin UV-Protection Films
  12. 32
    “…CD150(+), CD48(−) SKL populations initially engrafted in the central marrow region, utilizing only a subset of niches occupied by the parent SKL cells. …”
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    Extended time-lapse in vivo imaging of tibia bone marrow to visualize dynamic hematopoietic stem cell engraftment
  13. 33
    “…The SL group had higher energy and greater phosphorus, potassium, vitamin A, carotene, vitamin B1, and niacin intake than the non-school lunch (NSL) and skipping lunch (SKL) groups. …”
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    Associations between School Lunch and Obesity in Korean Children and Adolescents Based on the Korea National Health and Nutrition Examination Survey 2017–2019 Data: A Cross-Sectional Study
  14. 34
    por Hoveizi, Elham, Tavakol, Shima
    Publicado 2022
    “…Here, we present two differentiation protocols: the first one is induction with SKL2001; and the second one is with a combination of SKL2001 and zinc oxide nanoparticles (nZnO). …”
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    Differentiation of Human Wharton's Jelly Mesenchymal Stem Cells into SOX17 Expressing Cells Using a Wnt/ß-catenin Pathway Agonist on Polylactic Acid/Chitosan Nanocomposite Scaffold
  15. 35
    por Tan, Sheng, Chen, Jili
    Publicado 2021
    “…After treatment with si-HMGA2 in combination with Wnt/β-catenin agonists (SKL2001) or inhibitors (XAV-939), EMT was respectively enhanced or inhibited in IU-TAB-1 cells. …”
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    Small interfering-high mobility group A2 attenuates epithelial-mesenchymal transition in thymic cancer cells via the Wnt/β-catenin pathway
  16. 36
    por Hou, Rui, Jiang, Luo
    Publicado 2021
    “…The levels of CD44, NANOG, POU5F1, LINC00115, CD133, miR-30a and SOX9 were measured. …”
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    LINC00115 promotes stemness and inhibits apoptosis of ovarian cancer stem cells by upregulating SOX9 and inhibiting the Wnt/β-catenin pathway through competitively binding to microRNA-30a
  17. 37
    “…By inhibiting mRNA transcription or/and mRNA maturation, we showed that the 5.1 AAP3 mRNA did not decay after 180 min, but the 4.7 AAP3 mRNA presented a half-life decay of 32.6 +/− 5.0 min. …”
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    Axenic Leishmania amazonensis Promastigotes Sense both the External and Internal Arginine Pool Distinctly Regulating the Two Transporter-Coding Genes
  18. 38
    “…Vascular artery fragments and whole blood and serum samples were obtained during elective or organ retrieval surgery. Serum levels of sKL, TNFα and IL10, and gene expression levels of KL, TNF, IL10, NFKB1, DNMT1, and DNMT3A in PBCCs were measured. …”
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    Klotho expression in peripheral blood circulating cells is associated with vascular and systemic inflammation in atherosclerotic vascular disease
  19. 39
    “…On the EC surface, sKl interacts with vascular endothelial growth factor (VEGF) receptor-2 (VEGFR-2) and transient receptor potential canonical-1 (TRPC-1) cation channel to control EC homeostasis. …”
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    Proangiogenic effects of soluble α-Klotho on systemic sclerosis dermal microvascular endothelial cells
  20. 40
    “…Previous studies suggest that soluble klotho (sKL) could serve as a circulating hormone to mediate energy metabolism, but the detailed mechanism is poorly understood. …”
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    Soluble Klotho Improves Hepatic Glucose and Lipid Homeostasis in Type 2 Diabetes
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