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441por Mota, Ana Carolina, Dominguez, Monica, Weigert, Andreas, Snodgrass, Ryan G., Namgaladze, Dmitry, Brüne, Bernhard“…Mechanistically, lysosomal digestion and lysosomal acid lipase (LIPA) were required for PPAR and LXR activation, while PPARδ activation also demanded an active lysosomal phospholipase A(2) (PLA2G15). …”
Publicado 2021
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442por Zhu, Weifen, Zhang, Ziming, Gui, Weiwei, Shen, Zheng, Chen, Yixin, Yin, Xueyao, Liang, Li, Li, LinEnlace del recurso
Publicado 2022
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443por Mohan, John A., Dewar, Heidi, Snodgrass, Owyn E., Miller, Nathan R., Tanaka, Yosuke, Ohshimo, Seiji, Rooker, Jay R., Francis, Malcom, Wells, R. J. DavidEnlace del recurso
Publicado 2022
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445por Mariani, Luciano, Monfulleda, Núria, Alemany, Laia, Vizza, Enrico, Marandino, Ferdinando, Vocaturo, Amina, Benevolo, Maria, Quirós, Beatriz, Lloveras, Belén, Klaustermeier, Jo Ellen, Quint, Wim, de Sanjosé, Silvia, Bosch, F Xavier“…The five most common single HPV types among positive cases were: HPV16 (71/121; 58.7%), HPV18 (12/121; 9.9%), HPV31, HPV45 and HPV58 (5/121; 4.1% each). 2 (1.5%) of the single infections and 2 (1.5%) of the multiple infections contained low risk types. …”
Publicado 2010
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446
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447por La-Touche, Susannah, Lemetre, Christophe, Lambros, Maryou, Stankiewicz, Elzbieta, Ng, Charlotte K. Y., Weigelt, Britta, Rajab, Ramzi, Tinwell, Brendan, Corbishley, Cathy, Watkin, Nick, Berney, Dan, Reis-Filho, Jorge S.“…Recurrent gains were observed in chromosomes 1p13.3-q44 (88%), 3p12.3-q29 (86%), 5p15.33-p11 (67%) and 8p12-q24.3 (84%). Amplifications of 5p15.33-p11 and 11p14.1-p12 were found in seven (11%) and four (6%) cases, respectively. …”
Publicado 2016
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448por Nanda, Vashisht G. Y., Peng, Weiyi, Hwu, Patrick, Davies, Michael A., Ciliberto, Gennaro, Fattore, Luigi, Malpicci, Debora, Aurisicchio, Luigi, Ascierto, Paolo Antonio, Croce, Carlo M., Mancini, Rita, Spranger, Stefani, Gajewski, Thomas F., Wang, Yangyang, Ferrone, Soldano, Vanpouille-Box, Claire, Wennerberg, Erik, Pilones, Karsten A., Formenti, Silvia C., Demaria, Sandra, Tang, Haidong, Wang, Yang, Fu, Yang-Xin, Dummer, Reinhard, Puzanov, Igor, Tarhini, Ahmad, Chauvin, Joe-Marc, Pagliano, Ornella, Fourcade, Julien, Sun, Zhaojun, Wang, Hong, Sanders, Cindy, Kirkwood, John M., Chen, Tseng-hui Timothy, Maurer, Mark, Korman, Alan J., Zarour, Hassane M., Stroncek, David F., Huber, Veronica, Rivoltini, Licia, Thurin, Magdalena, Rau, Tilman, Lugli, Alessandro, Pagès, Franck, Camarero, Jorge, Sancho, Arantxa, Jommi, Claudio, de Coaña, Yago Pico, Wolodarski, Maria, Yoshimoto, Yuya, Gentilcore, Giusy, Poschke, Isabel, Masucci, Giuseppe V., Hansson, Johan, Kiessling, Rolf, Scognamiglio, Giosuè, Sabbatino, Francesco, Marino, Federica Zito, Anniciello, Anna Maria, Cantile, Monica, Cerrone, Margherita, Scala, Stefania, D’alterio, Crescenzo, Ianaro, Angela, Cirin, Giuseppe, Liguori, Giuseppina, Bott, Gerardo, Chapman, Paul B., Robert, Caroline, Larkin, James, Haanen, John B., Ribas, Antoni, Hogg, David, Hamid, Omid, Testori, Alessandro, Lorigan, Paul, Sosman, Jeffrey A., Flaherty, Keith T., Yue, Huibin, Coleman, Shelley, Caro, Ivor, Hauschild, Axel, McArthur, Grant A., Sznol, Mario, Callahan, Margaret K., Kluger, Harriet, Postow, Michael A., Gordan, RuthAnn, Segal, Neil H., Rizvi, Naiyer A., Lesokhin, Alexander, Atkins, Michael B., Burke, Matthew M., Ralabate, Amanda, Rivera, Angel, Kronenberg, Stephanie A., Agunwamba, Blessing, Ruisi, Mary, Horak, Christine, Jiang, Joel, Wolchok, Jedd, Ascierto, Paolo A., Liszkay, Gabriella, Maio, Michele, Mandalà, Mario, Demidov, Lev, Stoyakovskiy, Daniil, Thomas, Luc, de la Cruz-Merino, Luis, Atkinson, Victoria, Dutriaux, Caroline, Garbe, Claus, Wongchenko, Matthew, Chang, Ilsung, Koralek, Daniel O., Rooney, Isabelle, Yan, Yibing, Dréno, Brigitte, Sullivan, Ryan, Patel, Manish, Hodi, Stephen, Amaria, Rodabe, Boasberg, Peter, Wallin, Jeffrey, He, Xian, Cha, Edward, Richie, Nicole, Ballinger, Marcus, Smith, David C., Bauer, Todd M., Wasser, Jeffrey S., Luke, Jason J., Balmanoukian, Ani S., Kaufman, David R., Zhao, Yufan, Maleski, Janet, Leopold, Lance, Gangadhar, Tara C., Long, Georgina V., Michielin, Olivier, VanderWalde, Ari, Andtbacka, Robert H. I., Cebon, Jonathan, Fernandez, Eugenio, Malvehy, Josep, Olszanski, Anthony J., Gause, Christine, Chen, Lisa, Chou, Jeffrey, Stephen Hodi, F., Brady, Benjamin, Mortier, Laurent, Hassel, Jessica C., Rutkowski, Piotr, McNeil, Catriona, Kalinka-Warzocha, Ewa, Lebbé, Celeste, Ny, Lars, Chacon, Matias, Queirolo, Paola, Loquai, Carmen, Cheema, Parneet, Berrocal, Alfonso, Eizmendi, Karmele Mujika, Bar-Sela, Gil, Horak, Christine, Hardy, Helene, Weber, Jeffrey S., Grob, Jean-Jacques, Marquez-Rodas, Ivan, Schmidt, Henrik, Briscoe, Karen, Baurain, Jean-François, Wolchok, Jedd D., Pinto, Rosamaria, De Summa, Simona, Garrisi, Vito Michele, Strippoli, Sabino, Azzariti, Amalia, Guida, Gabriella, Guida, Michele, Tommasi, Stefania, Jacquelot, Nicolas, Enot, David, Flament, Caroline, Pitt, Jonathan M., Vimond, Nadège, Blattner, Carolin, Yamazaki, Takahiro, Roberti, Maria-Paula, Vetizou, Marie, Daillere, Romain, Poirier-Colame, Vichnou, la Semeraro, Michaë, Caignard, Anne, Slingluff, Craig L, Sallusto, Federica, Rusakiewicz, Sylvie, Weide, Benjamin, Marabelle, Aurélien, Kohrt, Holbrook, Dalle, Stéphane, Cavalcanti, Andréa, Kroemer, Guido, Di Giacomo, Anna Maria, Maio, Michaele, Wong, Phillip, Yuan, Jianda, Umansky, Viktor, Eggermont, Alexander, Zitvogel, Laurence, Anna, Passarelli, Marco, Tucci, Stefania, Stucci, Francesco, Mannavola, Mariaelena, Capone, Gabriele, Madonna, Antonio, Ascierto Paolo, Franco, Silvestris, Roberti, María Paula, Enot, David P., Semeraro, Michaela, Jégou, Sarah, Flores, Camila, Chen, Tseng-hui Timothy, Kwon, Byoung S., Anderson, Ana Carrizossa, Borg, Christophe, Aubin, François, Ayyoub, Maha, De Presbiteris, Anna Lisa, Cordaro, Fabiola Gilda, Camerlingo, Rosa, Fratangelo, Federica, Mozzillo, Nicola, Pirozzi, Giuseppe, Patriarca, Eduardo J., Caputo, Emilia, Motti, Maria Letizia, Falcon, Rosaria, Miceli, Roberta, Capone, Mariaelena, Madonna, Gabriele, Mallardo, Domenico, Carrier, Maria Vincenza, Panza, Elisabetta, De Cicco, Paola, Armogida, Chiara, Ercolano, Giuseppe, Botti, Gerardo, Cirino, Giuseppe, Sandru, Angela, Blank, Miri, Balatoni, Timea, Olasz, Judit, Farkas, Emil, Szollar, Andras, Savolt, Akos, Godeny, Maria, Csuka, Orsolya, Horvath, Szabolcs, Eles, Klara, Shoenfeld, Yehuda, Kasler, Miklos, Costantini, Susan, Capone, Francesca, Moradi, Farnaz, Berglund, Pontus, Leandersson, Karin, Linnskog, Rickard, Andersson, Tommy, Prasad, Chandra Prakash, Nigro, Cristiana Lo, Lattanzio, Laura, Wang, Hexiao, Proby, Charlotte, Syed, Nelofer, Occelli, Marcella, Cauchi, Carolina, Merlano, Marco, Harwood, Catherine, Thompson, Alastair, Crook, Tim, Bifulco, Katia, Ingangi, Vincenzo, Minopoli, Michele, Ragone, Concetta, Pessi, Antonello, Mannavola, Francesco, D’Oronzo, Stella, Felici, Claudia, Tucci, Marco, Doronzo, Antonio, Silvestris, Franco, Ferretta, Anna, Guida, Stefania, Maida, Imma, Cocco, Tiziana, Passarelli, Anna, Quaresmini, Davide, Franzese, Ornella, Palermo, Belinda, Di Donna, Cosmo, Sperduti, Isabella, Foddai, MariaLaura, Stabile, Helena, Gismondi, Angela, Santoni, Angela, Nisticò, Paola, Sponghini, Andrea P., Platini, Francesca, Marra, Elena, Rondonotti, David, Alabiso, Oscar, Fierro, Maria T., Savoia, Paola, Stratica, Florian, Quaglino, Pietro, Di Monta, Gianluca, Corrado, Caracò, Di Marzo, Massimiliano, Ugo, Marone, Di Cecilia, Maria Luisa, Nicola, Mozzillo, Fusciello, Celeste, Marra, Antonio, Guarrasi, Rosario, Baldi, Carlo, Russo, Rosa, Di Giulio, Giovanni, Faiola, Vincenzo, Zeppa, Pio, Pepe, Stefano, Gambale, Elisabetta, Carella, Consiglia, Di Paolo, Alessandra, De Tursi, Michele, Marra, Laura, De Murtas, Fara, Sorrentino, Valeria, Voinea, Silviu, Panaitescu, Eugenia, Bolovan, Madalina, Stanciu, Adina, Cinca, Sabin, Botti, Chiara, Aquino, Gabriella, Anniciello, Annamaria, Fortes, Cristina, Mastroeni, Simona, Caggiati, Alessio, Passarelli, Francesca, Zappalà, Alba, Capuano, Maria, Bono, Riccardo, Nudo, Maurizio, Marino, Claudia, Michelozzi, Paola, De Biasio, Valeria, Battarra, Vincenzo C., Formenti, Silvia, Ascierto, Maria Libera, McMiller, Tracee L., Berger, Alan E., Danilova, Ludmila, Anders, Robert A., Netto, George J., Xu, Haiying, Pritchard, Theresa S., Fan, Jinshui, Cheadle, Chris, Cope, Leslie, Drake, Charles G., Pardoll, Drew M., Taube, Janis M., Topalian, Suzanne L., Gnjatic, Sacha, Nataraj, Sarah, Imai, Naoko, Rahman, Adeeb, Jungbluth, Achim A., Pan, Linda, Venhaus, Ralph, Park, Andrew, Lehmann, Frédéric F., Lendvai, Nikoletta, Cohen, Adam D., Cho, Hearn J., Daniel, Speiser, Hirsh, Vera“…Stroncek Tumor microenvironment and biomarkers K13 Myeloid cells and tumor exosomes: a crosstalk for assessing immunosuppression? Veronica Huber, Licia Rivoltini K14 Update on the SITC biomarker taskforce: progress and challenges Magdalena Thurin World-wide immunoscore task force: an update K15 The immunoscore in colorectal cancer highlights the importance of digital scoring systems in surgical pathology Tilman Rau, Alessandro Lugli K16 The immunoscore: toward an integrated immunomonitoring from the diagnosis to the follow up of cancer’s patients Franck Pagès Economic sustainability of melanoma treatments: regulatory, health technology assessment and market access issues K17 Nivolumab, the regulatory experience in immunotherapy Jorge Camarero, Arantxa Sancho K18 Evidence to optimize access for immunotherapies Claudio Jommi ORAL PRESENTATIONS Molecular and immuno-advances O1 Ipilimumab treatment results in CD4 T cell activation that is concomitant with a reduction in Tregs and MDSCs Yago Pico de Coaña, Maria Wolodarski, Yuya Yoshimoto, Giusy Gentilcore, Isabel Poschke, Giuseppe V. …”
Publicado 2016
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449por Yu, Meigen, Ye, Hui, De-Paula, Ruth B., Mangleburg, Carl Grant, Wu, Timothy, Lee, Tom V., Li, Yarong, Duong, Duc, Phillips, Bridget, Cruchaga, Carlos, Allen, Genevera I., Seyfried, Nicholas T., Al-Ramahi, Ismael, Botas, Juan, Shulman, Joshua M.“…Homologs of two genes causing cholesterol storage disorders, Npc1a / NPC1 and Lip4 / LIPA, were independently confirmed as loss-of-function enhancers of αSyn-induced retinal degeneration. …”
Publicado 2023
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450por Nakai, Kenji, Oyanagi, Mayu, Hitomi, Jiro, Ogasawara, Kuniaki, Inoue, Takashi, Kobayashi, Masakazu, Nakai, Keiko, suwabe, Akira, Habano, Wataru, Baba, Toshiaki, Yoshida, Hiroshi, Ogawa, Akira“…Results: The allele frequency of PAI-1 –1965 delG (odds ratio (OR), 0.3; 95% confidence interval (CI), 0.2–0.6) and MTHFR (OR 1.3, 95% CI, 1.0–1.5) were significantly different between controls and cases with ICA stenosis by Fisher’s exact test. …”
Publicado 2009
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451por Keyvani, Hossein, Bokharaei-Salim, Farah, Monavari, Seyed Hamidreza, Esghaei, Maryam, Nassiri Toosi, Mohssen, Fakhim, Shahin, Sadigh, Zohreh Azita, Alavian, Seyed Moayed“…RESULTS: Of 45 patients, 4 (8.9% [95% CI: 4.4-15.6]) had detectable genomic HCV-RNA in their PBMC specimens. …”
Publicado 2013
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452por Loya, Asif, Serrano, Beatriz, Rasheed, Farah, Tous, Sara, Hassan, Mariam, Clavero, Omar, Raza, Muhammad, De Sanjosé, Silvia, Bosch, F. Xavier, Alemany, Laia“…HPV-DNA was detected by SPF10 broad-spectrum PCR followed by DNA enzyme immunoassay and genotyping by LiPA25. HPV-DNA prevalence was 87.5% (95%CI: 83.0–91.1), with 96.1% of cases histologically classified as squamous cell carcinoma. …”
Publicado 2016
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453por Bønløkke, Sara, Blaakær, Jan, Steiniche, Torben, Høgdall, Estrid, Jensen, Steffen Grann, Hammer, Anne, Balslev, Eva, Strube, Mikael Lenz, Knakkergaard, Helle, Lenz, Suzan“…There was no difference in HPV prevalence between cases and controls (2.15 vs. 1.00%, p = 0.61 and 1.08 vs. 0.00%, p = 0.48). …”
Publicado 2018
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454por Oh, Seung-Won, Lee, Jong-Eun, Shin, Eunsoon, Kwon, Hyuktae, Choe, Eun Kyung, Choi, Su-Yeon, Rhee, Hwanseok, Choi, Seung Ho“…After adjusting for age and sex, rs662799 located in the APOA5 gene were significantly associated with MetS. 15 SNPs in GCKR, C2orf16, APOA5, ZPR1, and BUD13 were associated with high triglyceride (TG). 14 SNPs in APOA5, ALDH1A2, LIPC, HERPUD1, and CETP, and 2 SNPs in MTNR1B were associated with low high density lipoprotein cholesterol (HDL-C) and high fasting blood glucose respectively. …”
Publicado 2020
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455por Reyes-Hernández, Diego Octavio, Morán-Torres, Adriana, Jimenez-Lima, Roberto, Cano-Valdez, Ana María, Cortés-González, Carlo César, Castro-Muñoz, Leonardo Josué, Olmedo-Nieva, Leslie, Maldonado-Frías, Silvia, Pazos-Salazar, Nidia Gary, de Jesús Marín-Aquíno, José, García-Carrancá, Alejandro, Carrillo-García, Adela, Muñoz-Bello, J. Omar, Lizano, Marcela, Manzo-Merino, Joaquín“…Methods: Retrolective study in Mexican OPSCC patients, where HPV prevalence, p16 and EGFR levels were assessed using INNO-LiPA and immunohistochemistry. Results: We found an HPV prevalence of 57.6% in OPSCC cases treated at a reference center in Mexico. …”
Publicado 2022
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456Publicado 1980Tabla de Contenidos: “…Carbohydrates -- v. 4. Lipids -- v. 5. Amino acids and derivatives -- v. 6. …”
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457por Zhao, Fang-Hui, Zhu, Feng-Cai, Chen, Wen, Li, Juan, Hu, Yue-Mei, Hong, Ying, Zhang, Yi-Ju, Pan, Qin-Jing, Zhu, Jia-Hong, Zhang, Xun, Chen, Yong, Tang, Haiwen, Zhang, Helen, Durand, Christelle, Datta, Sanjoy K, Struyf, Frank, Bi, Dan, HPV-039 study group“…Cervical specimens were tested for HPV DNA by SPF(10) PCR-DEIA-LiPA(25) version 1, and HPV-16/18 type-specific polymerase chain reaction. …”
Publicado 2014
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458por Chasman, Daniel I., Paré, Guillaume, Mora, Samia, Hopewell, Jemma C., Peloso, Gina, Clarke, Robert, Cupples, L. Adrienne, Hamsten, Anders, Kathiresan, Sekar, Mälarstig, Anders, Ordovas, José M., Ripatti, Samuli, Parker, Alex N., Miletich, Joseph P., Ridker, Paul M.“…In addition, genetic determinants of total IDL and total VLDL concentration were found at many loci, most strongly at LIPC (15q22.1) and APOC-APOE complex (19q13.32), respectively. …”
Publicado 2009
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459por Piana, Andrea, Sotgiu, Giovanni, Castiglia, Paolo, Pischedda, Stefania, Cocuzza, Clementina, Capobianco, Giampiero, Marras, Vincenzo, Dessole, Salvatore, Muresu, Elena“…METHODS: From 2007 to 2009 we consecutively enrolled women aged 15-54 years admitted to public and private outpatient settings. …”
Publicado 2011
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460por Michaleff, Zoe A., Campbell, Paul, Protheroe, Joanne, Rajani, Amit, Dunn, Kate M.“…METHODS: Consultations records specific to the knee region were extracted from a general practice consultation database (CiPCA) over a one year period. Knee consultation codes were organised into ‘symptom’ or ‘diagnosis’ (sub-categorised: ‘trauma’, ‘non-trauma’) categories. …”
Publicado 2017
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