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Mostrando 901 - 920 Resultados de 959 Para Buscar 'AB Volvo~', tiempo de consulta: 1.20s Limitar resultados
  1. 901
    “…Biliary complications have indeed been termed the “Achilles' heel” of LT, and while their prevention, diagnosis, and treatment have continued to evolve over the last two decades, various challenges and uncertainties persist. …”
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    Anastomotic Biliary Stricture Development after Liver Transplantation in the Setting of Retained Prophylactic Intraductal Pediatric Feeding Tube: Case and Review
  2. 902
    “…This review discusses about the single-domain antibodies (sdAbs), also called nanobodies, their structure, and their types against the infections of dreadful SARS-CoV-2 virus. …”
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    Online Artículo Texto
    Therapeutic applications of nanobodies against SARS-CoV-2 and other viral infections: Current update
  3. 903
    “…Since the approval of the first HER2 inhibitor, trastuzumab, in 1998, HER2-targeted drugs have rapidly evolved. Currently, targeting HER2 drugs mainly include monoclonal antibodies (mAbs), tyrosine kinase inhibitors (TKIs), and antibody-drug conjugates (ADCs). …”
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    Online Artículo Texto
    The History and Development of HER2 Inhibitors
  4. 904
    “…SARS-CoV-2 continues to evolve, with many variants evading clinically authorized antibodies. …”
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    Online Artículo Texto
    Antibodies targeting a quaternary site on SARS-CoV-2 spike glycoprotein prevent viral receptor engagement by conformational locking
  5. 905
    por Wang, Shenshen
    Publicado 2017
    “…Affinity maturation is a Darwinian process in which B lymphocytes evolve potent antibodies to encountered antigens and generate immune memory. …”
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    Optimal Sequential Immunization Can Focus Antibody Responses against Diversity Loss and Distraction
  6. 906
    “…This extensive glycosylation not only shields conserved regions of the protein from the immune system but also acts as a target for anti-HIV broadly neutralizing antibodies (bnAbs). In response to the host immune system, the HIV glycan shield is constantly evolving through mutations affecting both the positions and numbers of potential N-linked glycosylation sites (PNGSs). …”
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    Online Artículo Texto
    HIV-1 Glycan Density Drives the Persistence of the Mannose Patch within an Infected Individual
  7. 907
    “…Anti-CD38 mAbs can be safely administered to older patients with an impressive efficacy leading to a never-achieved-before survival rate with the triple association of anti-CD38 mAbs, lenalidomide, and dexamethasone. …”
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    30 Years of Improved Survival in Non-Transplant-Eligible Newly Diagnosed Multiple Myeloma
  8. 908
    “…A 57-year-old Caucasian man sought medical assistance due to back pain that evolved to paraplegia of the lower limbs. A thoracic CT scan demonstrated an important aneurysmatic lesion of the descending thoracic aorta causing erosion of the vertebral bodies and VDRL and FTA-abs positivity. …”
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    Aortic aneurysm in a patient with syphilis-related spinal pain and paraplegia
  9. 909
    “…Target detection requires the presence of both detector-Abs because the enzyme channeling event between GO and HRP will not occur unless both Abs are in close proximity. …”
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    Highly sensitive proximity mediated immunoassay reveals HER2 status conversion in the circulating tumor cells of metastatic breast cancer patients
  10. 910
    “…The spike (S) protein and its receptor-binding domain (RBD) of the coronavirus SARS-CoV-2 have been continually evolving, yielding the majority of significant missense mutations and new variants of concern. …”
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    Study of SARS-CoV-2 Spike Protein Wild-Type and the Variants of Concern Real-Time Interactions with Monoclonal Antibodies and Convalescent Human Serum
  11. 911
    “…METHODOLOGY/PRINCIPAL FINDINGS: Divergent selection on functional alleles was inferred from the higher genetic divergence at putative antigen binding sites (ABS) amino acid sequences than at putatively neutrally evolving sites at intron 1, exon 2 synonymous sequences and exon 2 amino acid residues outside the putative ABS. …”
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    MHC Adaptive Divergence between Closely Related and Sympatric African Cichlids
  12. 912
    “…To address the specific antibody targets that were affected by recent viral variants, we generated 43 monoclonal antibodies (mAbs) from 10 convalescent donors that bound three distinct domains of the SARS-CoV-2 spike. …”
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    Cross neutralization of emerging SARS-CoV-2 variants of concern by antibodies targeting distinct epitopes on spike
  13. 913
    “…Neutralizing antibodies (nAbs) have emerged as a therapeutic approach since the pandemic started. …”
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    Anti-SARS-CoV-2 and anti-cytokine storm neutralizing antibody therapies against COVID-19: Update, challenges, and perspectives
  14. 914
    “…To address the specific antibody targets that were affected by recent viral variants, we generated 43 monoclonal antibodies (mAbs) from 10 convalescent donors that bound three distinct domains of the SARS-CoV-2 spike. …”
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    Online Artículo Texto
    Cross-Neutralization of Emerging SARS-CoV-2 Variants of Concern by Antibodies Targeting Distinct Epitopes on Spike
  15. 915
    “…In particular, HIV-1 has evolved several mechanisms that reduce the premature “opening” of Env which exposes highly conserved epitopes recognized by non-neutralizing antibodies (nnAbs) capable of mediating antibody-dependent cellular cytotoxicity (ADCC). …”
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    HIV-1 Envelope Glycoproteins Proteolytic Cleavage Protects Infected Cells from ADCC Mediated by Plasma from Infected Individuals
  16. 916
    “…Most structurally characterized broadly neutralizing antibodies (bnAbs) against influenza A viruses (IAVs) target the conserved conformational epitopes of hemagglutinin (HA). …”
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    Unique binding pattern for a lineage of human antibodies with broad reactivity against influenza A virus
  17. 917
    “…We aimed to describe the evolving epidemiology and outcome of PCR-documented SARS-CoV-2 infection in KTR followed at our institution from March 2020 to May 2022. …”
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    Outcome of COVID-19 in Kidney Transplant Recipients Through the SARS-CoV-2 Variants Eras: Role of Anti-SARS-CoV-2 Monoclonal Antibodies
  18. 918
    “…In fact, the SPR biosensor best practices have evolved over the years, and several biases have been pointed out in the development of experimental SPR protocols. …”
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    Online Artículo Texto
    On the Use of Surface Plasmon Resonance Biosensing to Understand IgG-FcγR Interactions
  19. 919
    “…Virulent strains of these viruses are continually evolving and expanding their geographic range, thus rapid and sensitive screening assays are required to detect emerging viruses and monitor their prevalence and spread in mosquito populations. …”
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    Viral RNA Intermediates as Targets for Detection and Discovery of Novel and Emerging Mosquito-Borne Viruses
  20. 920
    “…However, it is apparent that there are epitopes on the virus that have evolved to remain largely constant due to their functional importance. …”
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    Online Artículo Texto
    Broad Reactivity Single Domain Antibodies against Influenza Virus and Their Applications to Vaccine Potency Testing and Immunotherapy
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