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1por Coego, Alberto, Julian, Jose, Lozano-Juste, Jorge, Pizzio, Gaston A., Alrefaei, Abdulwahed F., Rodriguez, Pedro L.“…E3 Ub ligases have been reported that target different ABA signaling core components, i.e., ABA receptors, PP2Cs, SnRK2s, and ABFs/ABI5 transcription factors. …”
Publicado 2021
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2por Melcher, Karsten, Xu, Yong, Ng, Ley-Moy, Zhou, X. Edward, Soon, Fen-Fen, Chinnusamy, Viswanathan, Suino-Powell, Kelly M., Kovach, Amanda, Tham, Fook S., Cutler, Sean R., Li, Jun, Yong, Eu-Leong, Zhu, Jian-Kang, Xu, H. Eric“…Crystal structures of the PYL2–pyrabactin and PYL1–pyrabactin–ABI1 complexes reveal the mechanism responsible for receptor-selective activation and inhibition, which enables us to design mutations that convert PYL1 to a pyrabactin-inhibited receptor and PYL2 to a pyrabactin-activated receptor, and to identify new pyrabactin-based ABA receptor agonists. Together, our results establish a new concept of ABA receptor antagonism, illustrate its underlying mechanisms, and provide a rational framework for discovering novel ABA receptor ligands.…”
Publicado 2010
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3por Cao, Minjie, Liu, Xue, Zhang, Yan, Xue, Xiaoqian, Zhou, X Edward, Melcher, Karsten, Gao, Pan, Wang, Fuxing, Zeng, Liang, Zhao, Yang, Zhao, Yang, Deng, Pan, Zhong, Dafang, Zhu, Jian-Kang, Xu, H Eric, Xu, YongEnlace del recurso
Publicado 2013
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4por Peterson, Francis C., Burgie, E. Sethe, Park, Sang-Youl, Jensen, Davin R., Weiner, Joshua J., Bingman, Craig A., Chang, Chia-An, Cutler, Sean R., Phillips, George N., Volkman, Brian F.“…We show that subtle differences between receptor binding pockets control ligand orientation between productive and non-productive modes. …”
Publicado 2010
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5“…Here we show that a ubiquitin-26S proteasome (UPS)-dependent pathway mediates microtubule disassembly and is required for ABA-induced stomatal closure. Moreover, we identify and characterize the ubiquitin E3 ligase MREL57 (MICROTUBULE-RELATED E3 LIGASE57) and the microtubule-stabilizing protein WDL7 (WAVE-DAMPENED2-LIKE7) in Arabidopsis and show that the MREL57-WDL7 module regulates microtubule disassembly to mediate stomatal closure in response to drought stress and ABA treatment. …”
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6por Kong, Lingyao, Cheng, Jinkui, Zhu, Yujuan, Ding, Yanglin, Meng, Jingjing, Chen, Zhizhong, Xie, Qi, Guo, Yan, Li, Jigang, Yang, Shuhua, Gong, Zhizhong“…Here, we report that ABI1 (ABA-INSENSITIVE 1) can interact with the U-box E3 ligases PUB12 and PUB13, but is ubiquitinated only when it interacts with ABA receptors in an in vitro assay. …”
Publicado 2015
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7“…Controlled protein turnover is an important component of ABA signalling. Here we show that the RING-type E3 ligase MYB30-INTERACTING E3 LIGASE 1 (MIEL1) regulates ABA sensitivity by promoting MYB96 turnover in Arabidopsis. …”
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8por Chen, Chengan, Wang, Can, Li, Junbo, Gao, Xiankui, Huang, Qikai, Gong, Yifu, Hao, Xiaolong, Maoz, Itay, Kai, Guoyin, Zhou, Wei“…Plant U-box (PUB) proteins are ubiquitin ligases (E3) involved in multiple biological processes and in response to plant stress. …”
Publicado 2022
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9por Lim, Chae Woo, Park, Chanmi, Kim, Jung-Hyun, Joo, Hyunhee, Hong, Eunji, Lee, Sung Chul“…CaREL1 encodes a cytoplasmic- and nuclear-localized protein with E3 ligase activity. CaREL1 expression was induced by abscisic acid (ABA) and drought. …”
Publicado 2017
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10“…The degradation of ABF1 and ABF3 are slower in vivo in seedlings lacking the ubiquitin E3 ligase KEEP ON GOING (KEG), and in vitro in extracts from keg seedlings, implicating KEG in their degradation. …”
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11“…In the present study, we show that the pepper (Capsicum annuum) Drought Induced RING type E3 ligase 1, CaDIR1, regulates the drought stress response via abscisic acid (ABA)-mediated signaling. …”
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12“…We present updated information on the components of the ABA signaling pathway, particularly on transcription factors modified by different E3 ligases. …”
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13por Zhao, Jinfeng, Zhao, Linlin, Zhang, Ming, Zafar, Syed Adeel, Fang, Jingjing, Li, Ming, Zhang, Wenhui, Li, Xueyong“…PYL9 interacted with two highly homologous plant U-box E3 ubiquitin ligases PUB22 and PUB23. In the cell-free degradation assay, the degradation of GST-PYL9 was accelerated in protein extract from plants overexpressing PUB22 but slowed down in protein extract from the pub22 pub23 double mutant. …”
Publicado 2017
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14por Li, Juan, Shi, Chaowei, Sun, Demeng, He, Yao, Lai, Chaohua, Lv, Pei, Xiong, Ying, Zhang, Longhua, Wu, Fangming, Tian, Changlin“…Reduced spectrum density mapping of the backbone relaxation data revealed that PYL10 was more flexible in ABA bound form than apo-PYL10, indicating an increased conformational entropy upon ligand binding. …”
Publicado 2015
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15“…Here, we show that the C3HC4-type RING finger E3 ligase, CaDTR1, regulates the drought stress response via ABA-mediated signalling. …”
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16por Liu, Guangchao, Liang, Jiaxuan, Lou, Lijuan, Tian, Miaomiao, Zhang, Xiangyun, Liu, Lijing, Zhao, Qingzhen, Xia, Ran, Wu, Yaorong, Xie, Qi, Yu, Feifei“…In addition to the direct regulation of VPS23A, we found that UBP12 and UBP13 also stabilized the E3 ligase XB3 ortholog 5 in A. thaliana (XBAT35.2) in response to ABA treatment. …”
Publicado 2022
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17por Tong, Shaofei, Chen, Ningning, Wang, Deyan, Ai, Fandi, Liu, Bao, Ren, Liwen, Chen, Yang, Zhang, Junlin, Lou, Shangling, Liu, Huanhuan, Liu, Jianquan, Ma, Tao, Jiang, Yuanzhong“…In this study, genome‐wide analyses of U‐box genes in poplars revealed that a U‐box E3 ubiquitin ligase gene, PalPUB79, is significantly induced following drought, salinity and ABA signalling. …”
Publicado 2021
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18“…The RING-type E3 ubiquitin ligases play an important role in plant growth, development, and defense responses to abiotic stresses and pathogens. …”
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19por Verma, Rakesh Kumar, Santosh Kumar, Vinjamuri Venkata, Yadav, Shashank Kumar, Pushkar, Suchitra, Rao, Mandali Venkateswara, Chinnusamy, Viswanathan“…PYL10 receptor appears to regulate its ligand ABA accumulation as PYL10 overexpressing transgenics accumulated 2–3.3-fold higher levels of ABA than that of WT in flag leaf at anthesis under non-stress conditions. …”
Publicado 2019
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20por Yu, Yongtao, Portolés, Sergi, Ren, Yi, Sun, Guangyu, Wang, Xiao-Fang, Zhang, Huihui, Guo, Shaogui“…Ubiquitination-mediated protein degradation plays important roles in ABA signal transduction and delivering responses to chloroplast stress signals in plants, but additional E3 ligases of protein ubiquitination remain to be identified to understand the complex signaling network. …”
Publicado 2022
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