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121“…Ubiquitin-conjugating enzyme E2s (UBCs), which catalyze the transfer of ubiquitin to substrate or E3 ligases, are key enzymes in ubiquitination modifications of target proteins. …”
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122por Hu, Wei, Ding, Zehong, Tie, Weiwei, Yan, Yan, Liu, Yang, Wu, Chunlai, Liu, Juhua, Wang, Jiashui, Peng, Ming, Xu, Biyu, Jin, Zhiqiang“…Further integrated analyses found that 30 tolerance genes, including transcription factor, heat shock protein, and E3 ubiquitin protein ligase, could be commonly regulated by osmotic, cold, and salt stresses. …”
Publicado 2017
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123por Wang, Qin, Chen, YaYu, Li, ShengPing, Yang, WenDi, Sun, LiFang, Jang, MeiQin, Wu, XiuLing, Wang, QianChao, Chen, Lifei, Wu, YunKun“…RGLG1 is an E3 ubiquitin ligase in Arabidopsis thaliana that participates in ABA signaling and regulates apical dominance. …”
Publicado 2020
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124por Gonzalez, Simon, Dumitrascuta, Maria, Eiselt, Emilie, Louis, Stevany, Kunze, Linda, Blasiol, Annalisa, Vivancos, Mélanie, Previti, Santo, Dewolf, Elke, Martin, Charlotte, Tourwé, Dirk, Cavelier, Florine, Gendron, Louis, Sarret, Philippe, Spetea, Mariana, Ballet, Steven“…[Image: see text] Fusion of nonopioid pharmacophores, such as neurotensin, with opioid ligands represents an attractive approach for pain treatment. …”
Publicado 2020
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125por Ding, Hao, Zhou, Guangzhen, Zhao, Long, Li, Xinyu, Wang, Yicheng, Xia, Chengcai, Xia, Zhiqiang, Wan, Yinglang“…Among the proteins encoded by these candidate genes were UDP-glucosyltransferase 85A2, the ABA-responsive element binding factor GBF4, E3 ubiquitin-protein ligase SIAH1, and LRR receptor-like serine/threonine-protein kinase ERECTA. …”
Publicado 2023
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126por Wang, Linlin, Fu, Hongbo, Zhao, Juan, Wang, Jiagang, Dong, Shuqi, Yuan, Xiangyang, Li, Xiaorui, Chen, Mingxun“…Glutathione S-transferases (GSTs) are a critical superfamily of multifunctional enzymes in plants. As a ligand or binding protein, GSTs regulate plant growth and development and detoxification. …”
Publicado 2023
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127por Zhao, Yuxuan, Huang, Shuotian, Wei, Lihui, Li, Meng, Cai, Tingting, Ma, Xiangqing, Shuai, Peng“…We speculated that AHL and TIFY family transcription factors, calmodulin, and E3 ubiquitin ligase in these proteins might be important phosphorus-related proteins. …”
Publicado 2023
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128“…We isolated and ligated pSH4 to the β-glucuronidase (GUS) reporter gene, and transformed it into a japonica rice cultivar to determine the multiple expression pattern of SH4. …”
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129por Moyano, Enriqueta, Martínez-Rivas, Félix J., Blanco-Portales, Rosario, Molina-Hidalgo, Francisco Javier, Ric-Varas, Pablo, Matas-Arroyo, Antonio J., Caballero, José Luis, Muñoz-Blanco, Juan, Rodríguez-Franco, Antonio“…They were placed into the ligation groups (pseudo-chromosomes) and described its physicochemical and genetic features. …”
Publicado 2018
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130“…Arabidopsis SIZ1 encodes a SUMO E3 ligase to regulate abiotic and biotic stress responses. …”
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131por Chung, Eunna, Choi, Youngsil, Park, Jiae, Nah, Wonheum, Park, Jaehyung, Jung, Yukdong, Lee, Joonno, Lee, Hyunji, Park, Soyoung, Hwang, Sunyoung, Kim, Seongcheol, Lee, Jongseok, Min, Dongjae, Jo, Junghwan, Kang, Shinyoung, Jung, Minyong, Lee, Phil Hyu, Ruley, H. Earl, Jo, DaewoongEnlace del recurso
Publicado 2020
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132por Gao, Shan-Shan, Guan, Hua, Yan, Shuang, Hu, Sai, Song, Man, Guo, Zong-Pei, Xie, Da-Fei, Liu, Yike, Liu, Xiaodan, Zhang, Shimeng, Zhou, Ping-KunEnlace del recurso
Publicado 2020
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133por Wang, Zhongxiao, Liu, Chi-Hsiu, Huang, Shuo, Fu, Zhongjie, Tomita, Yohei, Britton, William R., Cho, Steve S., Chen, Chuck T., Sun, Ye, Ma, Jian-xing, He, Xi, Chen, JingEnlace del recurso
Publicado 2020
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134por Peng, Li-Hua, Wang, Mao-Ze, Chu, Yang, Zhang, Lei, Niu, Jie, Shao, Hai-Tao, Yuan, Tie-Jun, Jiang, Zhi-Hong, Gao, Jian-Qing, Ning, Xing-HaiEnlace del recurso
Publicado 2020
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135por Flies, Andrew S., Darby, Jocelyn M., Lennard, Patrick R., Murphy, Peter R., Ong, Chrissie E. B., Pinfold, Terry L., De Luca, Alana, Lyons, A. Bruce, Woods, Gregory M., Patchett, Amanda L.Enlace del recurso
Publicado 2020
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136por Sade, Nir, Weng, Fei, Tajima, Hiromi, Zeron, Yarden, Zhang, Lei, Rubio Wilhelmi, Maria del Mar, Day, George, Peleg, Zvi, Blumwald, Eduardo“…Receptor-like cytoplasmic kinases (RLCKs) are receptor kinases that lack extracellular ligand-binding domains and have emerged as a major class of signaling proteins that regulate plant cellular activities in response to biotic/abiotic stresses and endogenous extracellular signaling molecules. …”
Publicado 2020
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137por Zhang, Yuzheng, Tan, Qiuping, Wang, Ning, Meng, Xiangguang, He, Huajie, Wen, Binbin, Xiao, Wei, Chen, Xiude, Li, Dongmei, Fu, Xiling, Li, Ling“…In addition, Y2H, Bimolecular fluorescence complementation (BiFC) assays verified that PpMYB52 interacts with a RING-type E3 ubiquitin ligase, PpMIEL1, which is upregulated during bud break may positively regulate peach bud break by ubiquitination-mediated degradation of PpMYB52. …”
Publicado 2022
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138“…Prescription opioids produce analgesia through activation of the mu-opioid receptor (MOR) and are major contributors to the current opioid crisis. Multifunctional ligands possessing activity at more than one receptor represent a prominent therapeutic approach for the treatment of pain with fewer adverse effects. …”
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139por Arcaro, Alexandre, Grégoire, Claude, Bakker, Talitha R., Baldi, Lucia, Jordan, Martin, Goffin, Laurence, Boucheron, Nicole, Wurm, Florian, van der Merwe, P. Anton, Malissen, Bernard, Luescher, Immanuel F.“…T1.4 hybridomas recognize a photoreactive Plasmodium berghei circumsporozoite (PbCS) peptide derivative (PbCS (4-azidobezoic acid [ABA])) in the context of H-2K(d), and permit assessment of TCR-ligand binding by TCR photoaffinity labeling. …”
Publicado 2001
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140por Lu, Pinyi, Hontecillas, Raquel, Horne, William T., Carbo, Adria, Viladomiu, Monica, Pedragosa, Mireia, Bevan, David R., Lewis, Stephanie N., Bassaganya-Riera, Josep“…Using this model, structure-based virtual screening was performed using compounds from NCI (National Cancer Institute) Diversity Set II, ChemBridge, ZINC natural products, and FDA-approved drugs databases. Several potential ligands were identified using molecular docking. In order to validate the anti-inflammatory efficacy of the top ranked compound (NSC61610) in the NCI Diversity Set II, a series of in vitro and pre-clinical efficacy studies were performed using a mouse model of dextran sodium sulfate (DSS)-induced colitis. …”
Publicado 2012
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