Mostrando 221 - 240 Resultados de 679 Para Buscar 'Ace Lossy~', tiempo de consulta: 0.97s Limitar resultados
  1. 221
    “…However, the neurological mechanism of Shu-Mu ACE for weight loss has not yet been elucidated. …”
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    Brain-Imaging Mechanisms on Female Abdominal Obesity Treated by “Shu-Mu” Acupoint Catgut Embedding and Compatibility Relation: Study Protocol for a 12-Week Randomized Controlled Trial
  2. 222
    “…For example, increased ketone body concentration during weight loss is an indication of elevated fat metabolism. …”
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    Measuring ketone bodies for the monitoring of pathologic and therapeutic ketosis
  3. 223
    “…Loss of GRP78 markedly reduced cell surface ACE2 expression and led to activation of markers of the unfolded protein response. …”
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    The chaperone GRP78 is a host auxiliary factor for SARS-CoV-2 and GRP78 depleting antibody blocks viral entry and infection
  4. 224
    “…In experiments with primary murine type II AEC, we found that exposure to hypoxia either in vivo (prior to isolation) or in vitro resulted in greatly increased AEC expression of both Ace2 (mRNA and protein) and of Tmprss2. However, when isolated type II AEC were maintained in culture over 5 days, with loss of type II cell characteristics and induction of type I cell features, Ace2 expression was greatly reduced, suggesting that this expression was a feature of only this subset of AEC. …”
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    Hypoxia induces expression of angiotensin‐converting enzyme II in alveolar epithelial cells: Implications for the pathogenesis of acute lung injury in COVID‐19
  5. 225
    “…The expression of ACE, ACE2 and NEP/CD10 was highest in clear cell renal cell carcinoma (CCRCC) and papillary renal cell carcinoma (PRCC). …”
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    Expression and activity of angiotensin-regulating enzymes is associated with prognostic outcome in clear cell renal cell carcinoma patients
  6. 226
    “…Glucocorticoid-induced glaucoma (GIG) is a chronic optic neuropathy caused by systemic or topical glucocorticoid (GC) treatment, which could eventually lead to permanent vision loss. To investigate the protective effects of rapamycin (RAP) on the trabecular cells during the development of GIG in mice, the effects of RAP on intraocular pressure (IOP), trabecular ultrastructure, and retinal ganglion cells (RGCs) were examined in C57BL/6J female mice treated with dexamethasone acetate (Dex-Ace). …”
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    Protective Effects of Rapamycin on Trabecular Meshwork Cells in Glucocorticoid-Induced Glaucoma Mice
  7. 227
    “…DHT upregulated urinary ACE2 in both diets, while neither treatment modified serum ACE2. …”
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    Cardiac and Renal SARS-CoV-2 Viral Entry Protein Regulation by Androgens and Diet: Implications for Polycystic Ovary Syndrome and COVID-19
  8. 228
    “…SARS-CoV-2 enters into the host cell by the spike protein binding with an ACE2 receptor present on the host cell. Developing safe and effective inhibitor appears an urgent need to interrupt the binding of SARS-CoV-2 spike protein with ACE2 receptor in order to reduce the SARS-CoV-2 infection. …”
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    Penta-peptide ATN-161 based neutralization mechanism of SARS-CoV-2 spike protein
  9. 229
    por Mende, Christian W.
    Publicado 2010
    “…PURPOSE: Chronic kidney disease has serious implications with a high risk for progressive loss of renal function, increased cardiovascular events as well as a substantial financial burden. …”
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    Application of Direct Renin Inhibition to Chronic Kidney Disease
  10. 230
    “…In transduced mice, the infection was short-term, with a rapid loss in body weight starting at day 2 with maximum weight loss at day 4, followed by subsequent recovery until day 10. …”
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    Early Isolates of SARS-CoV-2 Result in Different Pathogenesis in the Transduced Mouse Model of COVID-19
  11. 231
    “…Residue interaction networks analysis further revealed the binding of the two drugs at the exopeptidase site of hACE-2 reduced the number of interacting amino residues, subsequently leading to loss of interactions between the two proteins, with BHH showing better reduction in the molecular interaction and binding affinity than AMB. …”
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    Inhibitory mechanism of Ambroxol and Bromhexine Hydrochlorides as potent blockers of molecular interaction between SARS-CoV-2 spike protein and human angiotensin-converting Enzyme-2
  12. 232
    “…All spontaneous rough colony JAY270-derived isolates analyzed carried copy-neutral loss-of-heterozygosity (LOH) at the region of chromosome XII where ACE2 is located (ace2-A7/ace2-A7). …”
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    A Case Study of Genomic Instability in an Industrial Strain of Saccharomyces cerevisiae
  13. 233
    “…While ACE2 therapy prevented the loss of epithelial characteristics of hepatocytes and/or cholangiocytes in vivo, Ang‐(1‐7) prevented transdifferentiation of human cholangiocytes (H69 cells) into the collagen‐secreting myofibroblastic phenotype in vitro. …”
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    Liver‐Targeted Angiotensin Converting Enzyme 2 Therapy Inhibits Chronic Biliary Fibrosis in Multiple Drug‐Resistant Gene 2‐Knockout Mice
  14. 234
    “…METHODS: We searched EMBASE, PubMed, Ovid, and Web of Science to perform a meta‐analysis examining the correlation coefficients between three nephrometry scores (NSs) and warm ischemia time (WIT), estimated blood loss (EBL), operation time (OT), length of stay (LOS), and absolute change in eGFR (ACE) up to 25 January 2021. …”
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    Parallel comparison of R.E.N.A.L., PADUA, and C‐index scoring systems in predicting outcomes after partial nephrectomy: A systematic review and meta‐analysis
  15. 235
    “…The computational analysis, considering the case in which all the lysine residues in the system are subjected to non-enzymatic glycation, confirmed that lysine glycation causes a general loss of interactivity between wild-type (WT)-Spike-RBD and ACE2. …”
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    Omicron Variant of SARS-CoV-2 Virus: In Silico Evaluation of the Possible Impact on People Affected by Diabetes Mellitus
  16. 236
    “…METHODS: In this study, 53 832 and 43 106 new users of ACE‐I and CCB were included between 1995 and 2019, respectively. …”
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    Angiotensin‐converting enzyme inhibitors and risk of age‐related macular degeneration in individuals with hypertension
  17. 237
    “…In this study, we generate a human ACE2 (hACE2) transgenic mouse model in which the expression of hACE2 gene is regulated by hACE2 promoter. …”
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    Infection of SARS-CoV-2 causes severe pathological changes in mouse testis
  18. 238
    “…Infected Ace2™ mice exhibited weight loss and lung damage and inflammation, similar to COVID-19 patients. …”
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    A minimally-edited mouse model for infection with multiple SARS-CoV-2 strains
  19. 239
    por Csillik, Ovidiu, Asner, Gregory P.
    Publicado 2020
    “…Analyzed quarterly, the spatial evolution of ACE revealed 11.5 Tg C, 6.6 Tg C, 8.6 Tg C, and 10.1 Tg C lost between the third quarters of 2017 and 2018. …”
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    Near-real time aboveground carbon emissions in Peru
  20. 240
    “…Thus, destruction of ACE2 by SARS‐CoV‐2 results in loss of control of the pro‐inflammatory actions of Ang II and tissue destruction. …”
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    The interacting physiology of COVID‐19 and the renin‐angiotensin‐aldosterone system: Key agents for treatment
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