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301por Skrine Jeffers, Kia, Castellon-Lopez, Yelba, Grotts, Jonathan, Mangione, Carol M., Moin, Tannaz, Tseng, Chi-Hong, Turk, Norman, Frosch, Dominick L., Norris, Keith C., Duke, Christopher C., Moreno, Gerardo, Duru, O. Kenrik“…However, we did find that DPP attendance was associated with an increase in the overall ACE score (6.68 points, 95% CI 1.97–11.39, p = 0.005) and increased activation in 2 of the 3 ACE subscales (Commitment and Informed Choice). …”
Publicado 2019
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302por de Sousa, Antônio Kleiton, Magalhães, Diva de Aguiar, Ferreira, Jayro dos Santos, Barbosa, André Luiz dos Reis“…Hence, the presence of ACE2 is likely in the CNS to mediate the entry of the SARS-CoV-2 virus into neural tissue. …”
Publicado 2020
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303“…Poor definition of N, confusion with appetite loss, and reporting of N and/or V as a single entity may contribute to reporting variability and likely underestimation. …”
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304por Ramirez, J. M., Rodríguez, F. A., Echeverría, M. I., Vargas, A. L., Calderón, A. E., Miatello, R. M., Renna, N. F.“…Concomitant structural anomalies in this chromosome that associate partial loss of its long arm with duplications in its short arm are uncommon. …”
Publicado 2019
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305por Akisawa, Kazuki, Hatada, Ryo, Okuwaki, Koji, Mochizuki, Yuji, Fukuzawa, Kaori, Komeiji, Yuto, Tanaka, Shigenori“…By two separate calculations for the RBD complexes with angiotensin-converting enzyme 2 (ACE2) (6M0J) and B38 Fab antibody (7BZ5), it was found that the binding with ACE2 or antibody partially compensated for this stabilization loss of RBD.…”
Publicado 2021
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306por Yamamoto, Toru, Koyama, Yuhei, Imai, Yuzo, Sawada, Emi, Kishimoto, Naotaka, Seo, Kenji“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections cause loss or alteration of taste and smell as early symptoms and sequelae, but the detailed mechanism remains unclear. …”
Publicado 2022
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307por Papadopoulos, Georgios, Sintou, Eleni, Siminelakis, Stavros, Koletsis, Efstratios, Baikoussis, Nikolaos G, Apostolakis, Efstratios“…Preoperative medication by inhibitors of angiotensin-converting enzyme (ACE) in coronary artery patients predisposes to vasoplegic shock early after coronary artery bypass grafting. …”
Publicado 2010
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308Resting State Networks Related to the Maintenance of Good Cognitive Performance During Healthy Agingpor Maesawa, Satoshi, Mizuno, Satomi, Bagarinao, Epifanio, Watanabe, Hirohisa, Kawabata, Kazuya, Hara, Kazuhiro, Ohdake, Reiko, Ogura, Aya, Mori, Daisuke, Nakatsubo, Daisuke, Isoda, Haruo, Hoshiyama, Minoru, Katsuno, Masahisa, Saito, Ryuta, Ozaki, Norio, Sobue, Gen“…After preprocessing, several factors associated with age including the ACE-R total score, scores of five domains, sub-scores of ACE-R, and brain volumes were tested. …”
Publicado 2021
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309por Oliveras, Anna, Molina, Lluís, Goday, Albert, Sans, Laia, Riera, Marta, Vazquez, Susana, Benaiges, David, Granados, Ana Marina, Ramon, José Manuel, Pascual, Julio“…In addition to the respective baseline value, final values of PWT and RWT were dependent on 12‐month Δ of PRA, ACE, and ACE/ACE2 (p < .03 for all). We conclude that there are cardiac changes post‐BS in patients with severe obesity, normotensives included. …”
Publicado 2020
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310por Jeong, Minjin, Ocwieja, Karen E., Han, Dongjun, Wackym, P. Ashley, Zhang, Yichen, Brown, Alyssa, Moncada, Cynthia, Vambutas, Andrea, Kanne, Theodore, Crain, Rachel, Siegel, Noah, Leger, Valerie, Santos, Felipe, Welling, D. Bradley, Gehrke, Lee, Stankovic, Konstantina M.“…Both OPCs and SCPs express ACE2, TMPRSS2, and FURIN, with lower ACE2 and FURIN expression in SCPs. …”
Publicado 2021
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311“…BACKGROUND: Evidence on the effects of Acute Care for Elders (ACE) units in frail older adults remains limited. …”
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312por Halfmann, Peter J., Iida, Shun, Iwatsuki-Horimoto, Kiyoko, Maemura, Tadashi, Kiso, Maki, Scheaffer, Suzanne M., Darling, Tamarand L., Joshi, Astha, Loeber, Samantha, Singh, Gagandeep, Foster, Stephanie L., Ying, Baoling, Case, James Brett, Chong, Zhenlu, Whitener, Bradley, Moliva, Juan, Floyd, Katharine, Ujie, Michiko, Nakajima, Noriko, Ito, Mutsumi, Wright, Ryan, Uraki, Ryuta, Warang, Prajakta, Gagne, Matthew, Li, Rong, Sakai-Tagawa, Yuko, Liu, Yanan, Larson, Deanna, Osorio, Jorge E., Hernandez-Ortiz, Juan P., Henry, Amy R., Ciuoderis, Karl, Florek, Kelsey R., Patel, Mit, Odle, Abby, Wong, Lok-Yin Roy, Bateman, Allen C., Wang, Zhongde, Edara, Venkata-Viswanadh, Chong, Zhenlu, Franks, John, Jeevan, Trushar, Fabrizio, Thomas, DeBeauchamp, Jennifer, Kercher, Lisa, Seiler, Patrick, Gonzalez-Reiche, Ana Silvia, Sordillo, Emilia Mia, Chang, Lauren A., van Bakel, Harm, Simon, Viviana, Douek, Daniel C., Sullivan, Nancy J., Thackray, Larissa B., Ueki, Hiroshi, Yamayoshi, Seiya, Imai, Masaki, Perlman, Stanley, Webby, Richard J., Seder, Robert A., Suthar, Mehul S., García-Sastre, Adolfo, Schotsaert, Michael, Suzuki, Tadaki, Boon, Adrianus C. M., Diamond, Michael S., Kawaoka, Yoshihiro“…Here, using the collaborative network of the SARS-CoV-2 Assessment of Viral Evolution (SAVE) programme of the National Institute of Allergy and Infectious Diseases (NIAID), we evaluated the ability of several B.1.1.529 isolates to cause infection and disease in immunocompetent and human ACE2 (hACE2)-expressing mice and hamsters. Despite modelling data indicating that B.1.1.529 spike can bind more avidly to mouse ACE2 (refs. (3,4)), we observed less infection by B.1.1.529 in 129, C57BL/6, BALB/c and K18-hACE2 transgenic mice than by previous SARS-CoV-2 variants, with limited weight loss and lower viral burden in the upper and lower respiratory tracts. …”
Publicado 2022
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313por Larner, A.J.“…RESULTS: Weighted comparison calculations suggested a net benefit for ACE-R, MoCA, and MMP compared to MMSE, but a net loss for TYM test compared to MMSE. …”
Publicado 2013
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314por Gonzalez, Andrea, Orozco-Aguilar, Josué, Achiardi, Oscar, Simon, Felipe, Cabello-Verrugio, Claudio“…It has been well established that angiotensin-converting enzyme type 2 (ACE2) is the primary cellular receptor for SARS-CoV-2. …”
Publicado 2020
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315“…Research has shown that the causative virus, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), uses the angiotensin-converting enzyme II (ACE-II) receptor to attack host cells. These ACE-II receptors are present essentially in all organs, acting as a route of entry for SARS-CoV-2 to cause a wide variety of manifestations. …”
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316por Veronesi, Francesca, Contartese, Deyanira, Martini, Lucia, Visani, Andrea, Fini, Milena“…We speculate that ACE2 and serine proteases together with an intense inflammation, immobilization and malnutrition could be the responsible for muscle weakness, altered bone remodeling, increase in bone fracture risk and inflammatory joint pathologies. …”
Publicado 2022
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317por Lee, Na Yun, Lee, Youn Woo, Hong, Seung-Min, On, Dain, Yoon, Gyeong Min, An, See-He, Nam, Ki Taek, Seo, Jun-Young, Shin, Jeon-Soo, Choi, Yang-Kyu, Oh, Seung Hyun, Yun, Jun-Won, Lee, Ho Young, Choi, Kang-Seuk, Seong, Je Kyung, Park, Jun Won“…CONCLUSION: Lethal conditions, such as severe body weight loss and encephalopathy, can occur in Omicron-infected K18-hACE2 mice. …”
Publicado 2023
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318“…ACE inhibitors and ARBs (angiotensin receptor blockers) have been shown to attenuate radiation injuries in animal models of lethal gamma irradiation. …”
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319por Zost, Seth J., Gilchuk, Pavlo, Case, James Brett, Binshtein, Elad, Chen, Rita E., Nkolola, Joseph P., Schäfer, Alexandra, Reidy, Joseph X., Trivette, Andrew, Nargi, Rachel S., Sutton, Rachel E., Suryadevara, Naveenchandra, Martinez, David R., Williamson, Lauren E., Chen, Elaine C., Jones, Taylor, Day, Samuel, Myers, Luke, Hassan, Ahmed O., Kafai, Natasha M., Winkler, Emma S., Fox, Julie M., Shrihari, Swathi, Mueller, Benjamin K., Meiler, Jens, Chandrashekar, Abishek, Mercado, Noe B., Steinhardt, James J., Ren, Kuishu, Loo, Yueh-Ming, Kallewaard, Nicole L., McCune, Broc T., Keeler, Shamus P., Holtzman, Michael J., Barouch, Dan H., Gralinski, Lisa E., Baric, Ralph S., Thackray, Larissa B., Diamond, Michael S., Carnahan, Robert H., Crowe, James E.“…From a larger panel of human monoclonal antibodies (mAbs) targeting the spike (S) glycoprotein(5), we identified several that exhibited potent neutralizing activity and fully blocked the receptor-binding domain of S (S(RBD)) from interacting with human ACE2 (hACE2). Competition-binding, structural, and functional studies allowed clustering of the mAbs into classes recognizing distinct epitopes on the S(RBD) as well as distinct conformational states of the S trimer. …”
Publicado 2020
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320por Peter, Antonia Sophia, Roth, Edith, Schulz, Sebastian R., Fraedrich, Kirsten, Steinmetz, Tobit, Damm, Dominik, Hauke, Manuela, Richel, Elie, Mueller‐Schmucker, Sandra, Habenicht, Katharina, Eberlein, Valentina, Issmail, Leila, Uhlig, Nadja, Dolles, Simon, Grüner, Eva, Peterhoff, David, Ciesek, Sandra, Hoffmann, Markus, Pöhlmann, Stefan, McKay, Paul F., Shattock, Robin J., Wölfel, Roman, Socher, Eileen, Wagner, Ralf, Eichler, Jutta, Sticht, Heinrich, Schuh, Wolfgang, Neipel, Frank, Ensser, Armin, Mielenz, Dirk, Tenbusch, Matthias, Winkler, Thomas H., Grunwald, Thomas, Überla, Klaus, Jäck, Hans‐Martin“…Antibodies from both clusters markedly reduced viral spread in mice transgenic for human ACE2 and protected the animals from SARS‐CoV‐2‐induced weight loss. …”
Publicado 2021
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