Mostrando 161 - 180 Resultados de 679 Para Buscar 'Ace Lossy~', tiempo de consulta: 2.53s Limitar resultados
  1. 161
    “…Ang II-mediated cardiac dysfunction and hypertrophy were augmented in apelin knockout mice. The loss of apelin increased the ratio of angiotensin-converting enzyme (ACE) to ACE2 expression in the Ang II-stressed hearts, and Ang II-induced cardiac fibrosis was markedly enhanced in apelin knockout mice. mRNA expression of pro-fibrotic genes, such as transforming growth-factor beta (TGF-β) signaling, were significantly upregulated in apelin knockout hearts. …”
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    Loss of Apelin Augments Angiotensin II-Induced Cardiac Dysfunction and Pathological Remodeling
  2. 162
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    Osteoclast-mediated bone loss observed in a COVID-19 mouse model
  3. 163
    “…However, SARS-CoV-2 mediated deregulation of diabetes pathophysiology and comorbidity that links the skeletal bone loss remain unclear. We used both streptozocin-induced type 2 diabetes (T2DM) mouse and hACE2 transgenic mouse to enable SARS-CoV-2-receptor binding domain (RBD) mediated abnormal glucose metabolism and bone loss phenotype in mice. …”
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    Diabetic Covid-19 severity: Impaired glucose tolerance and pathologic bone loss
  4. 164
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    Staphylococcus aureus cell growth and division are regulated by an amidase that trims peptides from uncrosslinked peptidoglycan
  5. 165
    “…The loss of biodiversity in the ecosystems has created the general conditions that have favored and, in fact, made possible, the insurgence of the COVID-19 pandemic. …”
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    Biodiversity loss and COVID-19 pandemic: The role of bats in the origin and the spreading of the disease
  6. 166
    “…BACKGROUND: Despite the enhanced progress in identifying a number of leading causes to fetal miscarriage, still some women suffer from recurrent pregnancy loss (RPL) for unknown cause. A hidden genetic influence of coexisting hereditary thrombophilia was assumed to have a role. …”
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    The Prevalence Of Specific Gene Polymorphisms Related To Thrombophilia In Egyptian Women With Recurrent Pregnancy Loss
  7. 167
    “…The acute loss of taste and smell following COVID-19 are hallmark symptoms that affect 20–85% of patients. …”
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    Potential pharmacologic treatments for COVID-19 smell and taste loss: A comprehensive review
  8. 168
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    Correlating Ocular Physiology and Visual Function with Mild Cognitive Loss in Senior Citizens in Taiwan
  9. 169
    “…Loss of ACE2 was associated with a marked increase in renal lipid peroxidation product formation and activation of mitogen-activated protein kinase and extracellular signal-regulated kinases 1 and 2 in glomeruli, events that are also prevented by angiotensin II type-1 receptor blockade. …”
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    Loss of Angiotensin-Converting Enzyme-2 Leads to the Late Development of Angiotensin II-Dependent Glomerulosclerosis
  10. 170
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    Use of medicines for covid-19 treatment in patients with loss of kidney function: a narrative review
  11. 171
    “…The objective was to evaluate the reduction in 24-h proteinuria in T2DM patients with nephropathy by weight loss, with conventional therapy (angiotensin-converting enzyme [ACE] inhibitors) as the control arm. …”
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    Weight loss for reduction of proteinuria in diabetic nephropathy: Comparison with angiotensin-converting enzyme inhibitor therapy
  12. 172
    “…The 24-h IOP phase correlated with RGC loss (p < 0.0001). The internal phase shift between IOP and body temperature gradually increased with POAG progression (p < 0.001). …”
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    Disruption of 24-Hour Rhythm in Intraocular Pressure Correlates with Retinal Ganglion Cell Loss in Glaucoma
  13. 173
    “…BACKGROUND: Genetic loss of function of AGT (angiotensinogen), REN (renin), ACE (angiotensin-converting enzyme), or AGTR1 (type-1 angiotensin II receptor) leads to renal tubular dysgenesis (RTD). …”
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    Functional tests to guide management in an adult with loss of function of type-1 angiotensin II receptor
  14. 174
    “…We compared one-year clinical outcomes in patients with and without appetite loss at discharge. RESULTS: In the multivariable logistic regression analysis using 19 clinical and laboratory factors with P value < 0.1 by univariate analysis, BMI < 22 kg/m(2) (odds ratio (OR): 1.57, 95% confidence interval (CI): 1.11–2.24, P = 0.01), CRP >1.0mg/dL (OR: 1.49, 95%CI: 1.04–2.14, P = 0.03), and presence of edema at discharge (OR: 4.30, 95%CI: 2.99–6.22, P<0.001) were associated with an increased risk of appetite loss at discharge, whereas ambulatory status (OR: 0.57, 95%CI: 0.39–0.83, P = 0.004) and the use of ACE-I/ARB (OR: 0.70, 95% CI: 0.50–0.98, P = 0.04) were related to a decreased risk in the presence of appetite loss. …”
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    Appetite loss at discharge from acute decompensated heart failure: Observation from KCHF registry
  15. 175
    “…Numerous reports have described loss of in vitro neutralisation activity of Ronapreve and other monoclonal antibodies for BA.1 Omicron and subsequent sub-lineages of the Omicron variant. …”
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    Ronapreve (REGN-CoV; casirivimab and imdevimab) reduces the viral burden and alters the pulmonary response to the SARS-CoV-2 Delta variant (B.1.617.2) in K18-hACE2 mice using an experimental design reflective of a treatment use case
  16. 176
    “…CONCLUSIONS: The rs1799964 in the TNF gene and rs4291 in the ACE gene are new associations when the definition of cachexia is based on a combination of WL and LSMI. …”
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    New genetic signatures associated with cancer cachexia as defined by low skeletal muscle index and weight loss
  17. 177
    “…Periodontal disease (PD) is a prevalent inflammatory disease with the most severe consequence being the loss of the alveolar bone and teeth. We therefore aimed to evaluate the effects of telmisartan (TELM), an angiotensin II type 1 receptor (Agtr1) antagonist, on the PD-induced alveolar bone loss, in Wistar (W) and Spontaneous Hypertensive Rats (SHRs). …”
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    Telmisartan Prevents Alveolar Bone Loss by Decreasing the Expression of Osteoclasts Markers in Hypertensive Rats With Periodontal Disease
  18. 178
    “…BACKGROUND: The clinical problem of a “pure volume overload” as in isolated mitral or aortic regurgitation currently has no documented medical therapy that attenuates collagen loss and the resultant left ventricular (LV) dilatation and failure. …”
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    Cardiac Kallikrein-Kinin System Is Upregulated in Chronic Volume Overload and Mediates an Inflammatory Induced Collagen Loss
  19. 179
    “…BACKGROUND: Recurrent pregnancy loss (RPL) defined by two or more failed pregnancies before 20 weeks of gestation. …”
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    Association of plasminogen activator inhibitor-1 and angiotensin converting enzyme polymorphisms with recurrent pregnancy loss in Iranian women
  20. 180
    “…Clinical case: A 55 year-old Caucasian women with a 2 years history of increasing concentric visual field loss, blurred vision, photophobia, nyctalopia (loss of night vision), dyschromatopsia (colour blindness), and new visual migraines with bright aura after commencing ezetimbe and montelukast therapy around the same time. …”
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    ODP142 Concentric Reversible Visual Field Loss, Nyctalopia and Dyschromatopsia With Ezetimibe Therapy - A Case Report
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