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581por Yamamoto, Kenji, Ishibashi, Osamu, Sugiura, Keisuke, Ubatani, Miki, Sakaguchi, Masaya, Nakatsuji, Masatoshi, Shimamoto, Shigeru, Noda, Masanori, Uchiyama, Susumu, Fukutomi, Yuma, Nishimura, Shigenori, Inui, Takashi“…Substituting three successive amino acids in these sites to triple alanine decreased IgE reactivity to the allergen. …”
Publicado 2019
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582“…The prodrugs showed great stability towards hydrolytic degradation under neutral, mildly acidic and mildly basic conditions. The carbamate prodrug also showed to be stable in rat serum. …”
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583por Li, Jiwei, Zhang, Xiangmin, Bai, Bowen, Zhang, Mengmeng, Ma, Weiwei, Lin, Yuezhi, Wang, Xiaojun, Wang, Xue-Feng“…Grev is encoded by a novel transcript with a single splicing event that was identified using reverse transcription-PCR (RT-PCR) and RNA-seq in EIAV-infected horse tissues and cells. Grev is about 18 kDa in size, comprises the first 18 amino acids (aa) of Gag protein together with the last 82 aa of Rev, and was detected in EIAV-infected cells. …”
Publicado 2022
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584por Contreras-Aguilar, María Dolores, Rubio, Camila Peres, González-Arostegui, Luis Guillermo, Martín-Cuervo, María, Cerón, Jose J., Ayala, Ignacio, Henriksen, Ida-Marie Holm, Jacobsen, Stine, Hansen, Sanni“…Horses suffering from CIE had increases in serum uric acid associated with their systemic inflammatory response and outcome of the disease. …”
Publicado 2022
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585por Burnouf, Thierry, Griffiths, Elwyn, Padilla, Ana, Seddik, Salwa, Stephano, Marco Antonio, Gutiérrez, José-María“…They are obtained by fractionating plasma collected from immunized horses or, less frequently, sheep. Manufacturing processes usually include pepsin digestion at acid pH, papain digestion, ammonium sulphate precipitation, caprylic acid precipitation, heat coagulation and/or chromatography. …”
Publicado 2004
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586por Li, Xiao Bin, Huang, Xin Xin, Li, Qian, Li, Xuan Yue, Li, Jia Hao, Li, Chao, He, Lin Jiao, Jing, Hong Xin, Yang, Kai Lun“…BACKGROUND: Compared with the stomach of ruminant cattle, the stomach of horse is small and mainly for chemical digestion, but the microorganisms in the stomach play an important role in maintaining the homeostasis of the internal environment. …”
Publicado 2022
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587por Badenhorst, Marcha, Page, Patrick, Ganswindt, Andre, Laver, Peter, Guthrie, Alan, Schulman, Martin“…Nasal swabs for quantitative real-time polymerase chain reaction (qPCR) assay to detect EHV-1 and -4 nucleic acid and blood samples for enzyme-linked immunosorbent assay for EHV-1 and -4 antibodies were collected from all horses on arrival and departure. …”
Publicado 2015
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588“…BACKGROUND: Intra-articular inflammation resulting in lameness is a common health problem in horses. Exogenous intra-articular hyaluronic acid has been shown to provide an analgesic effect and reduce pain in equine and human osteoarthritis. …”
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589por Tuniyazi, Maimaiti, He, Junying, Guo, Jian, Li, Shuang, Zhang, Naisheng, Hu, Xiaoyu, Fu, Yunhe“…In this study we aimed to investigate changes of the gut microbiota and metabolomics in oligofructose-induced laminitis of horses. RESULTS: Animals submitted to treatment with oligofructose had lower fecal pH but higher lactic acid, histamine, and Lipopolysaccharide (LPS) in serum. …”
Publicado 2021
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590por Bourebaba, Lynda, Kornicka-Garbowska, Katarzyna, Al Naem, Mohamad, Röcken, Michael, Łyczko, Jacek, Marycz, Krzysztof“…OBJECTIVES: This investigation aimed to elucidate whether selective inhibition of PTP1B using MSI-1436 compound may improve and restore the defective adipogenicity of ASCs isolated from EMS-affected horses. METHODS: Equine ASC EMS cells were cultured under adipogenic conditions in the presence of PTP1B inhibitor and were subsequently tested for expression of the main adipogenic-related genes using RT-qPCR, changes in free fatty acid profiles by means of GC-MS technique, and for mitochondrial dynamics improvement through the analysis of mitochondrial transmembrane potential and oxidative stress. …”
Publicado 2021
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591“…Prevalence is highest in performance horses, but the disease has been documented across many breeds and ages, including in feral horses and foals. …”
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592por Hernando, Sara, Nikolakopoulou, Polyxeni, Voulgaris, Dimitrios, Hernandez, Rosa Maria, Igartua, Manoli, Herland, Anna“…We have previously developed polyunsaturated fatty acids (PUFA)-based nanostructured lipid carriers (NLC), namely DHAH-NLC. …”
Publicado 2022
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593por Liu, Lianxing, Wan, Yanmin, Wu, Lan, Sun, Jianping, Li, Huiguang, Li, Haishan, Ma, Liying, Shao, Yiming“…The direction of the mutations was made towards the amino acids conserved in the two EIAV vaccine strains, distinguishing them from the two wild-type strains. …”
Publicado 2010
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594por Goodman, Laura B, Loregian, Arianna, Perkins, Gillian A, Nugent, Josie, Buckles, Elizabeth L, Mercorelli, Beatrice, Kydd, Julia H, Palù, Giorgio, Smith, Ken C, Osterrieder, Nikolaus, Davis-Poynter, Nicholas“…Infection with equid herpesvirus type 1 (EHV-1) leads to respiratory disease, abortion, and neurologic disorders in horses. Molecular epidemiology studies have demonstrated that a single nucleotide polymorphism resulting in an amino acid variation of the EHV-1 DNA polymerase (N752/D752) is significantly associated with the neuropathogenic potential of naturally occurring strains. …”
Publicado 2007
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595por Perglione, Cecilia Olguin, Gildea, Sarah, Rimondi, Agustina, Miño, Samuel, Vissani, Aldana, Carossino, Mariano, Cullinane, Ann, Barrandeguy, Maria“…The HA1 of viruses identified in horses in racing facilities in Maroñas, Uruguay, and in Palermo, Argentina, displayed 100% amino acid sequence identity and were identical to that of a virus isolated in Dubai in 2012, from vaccinated endurance horses recently imported from Uruguay. …”
Publicado 2015
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596por Favaro, Patricia Filippsen, Fernandes, Wilson Roberto, Reischak, Dilmara, Brandão, Paulo Eduardo, Silva, Sheila Oliveira de Souza, Richtzenhain, Leonardo José“…Equine influenza is one of the major respiratory infectious diseases in horses. An equine influenza virus outbreak was identified in vaccinated and unvaccinated horses in a veterinary school hospital in São Paulo, SP, Brazil, in September 2015. …”
Publicado 2017
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597por Setoh, Yin Xiang, Periasamy, Parthiban, Peng, Nias Yong Gao, Amarilla, Alberto A., Slonchak, Andrii, Khromykh, Alexander A.“…Further analysis with individual amino acid mutants identified two amino acid residues in the helicase domain primarily responsible for this difference. …”
Publicado 2017
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598por Toh, Xinyu, Soh, Moi Lien, Ng, Mee Keun, Yap, Shew Choo, Harith, Nurshilla, Fernandez, Charlene Judith, Huangfu, Taoqi“…Equine influenza is a major cause of respiratory infections in horses and can spread rapidly despite the availability of commercial vaccines. …”
Publicado 2019
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599por McGorum, Bruce C, Pirie, R Scott, Glendinning, Laura, McLachlan, Gerry, Metcalf, James S, Banack, Sandra A, Cox, Paul A, Codd, Geoffrey A“…Neither DAB nor the cyanobacterial neurotoxins β-N-methylamino-L-alanine and N-(2-aminoethyl) glycine were detected in neural tissue from 6 EGS horses, 2 EMND horses and 7 control horses. Phormidium was present in low numbers on plants where horses had unexplained hepatopathy. …”
Publicado 2015
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600“…A rebound increase in gastric acid occurs in humans when acid-suppressing therapy with omeprazole ceases and might result in ‘rebound ulcers’. …”
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